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16 Cards in this Set
- Front
- Back
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What is the difference b/t plasma and serum?
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Serum does not have fibrinogen.
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What is the normal range for plasma proteins?
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6.5-8.3 g/dl
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What are total globulins and what is a normal range?
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The difference b/t total protein and albumin (2-3.5 g/dl)
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What is electrophoresis? /Can you give an example of its use?
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Protein fractions are separated in distinct zones when an electric current is applied to the sample on a solid support in a buffer solution./ It detects variations in Ig's.
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What is the normal serum value for prealbumin?
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40 mg/dl
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What is the normal range for albumin?
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3.5-4.5 g/dl
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What is the role of haptoglobin(a type of alpha-globulin)?
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It combines with Hb (which is released from rbc lysis) to preserve iron.
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What is the major component of beta globulin and what is its action?
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Transferrin- transports ferric ions from the intracellular ferritin to the bone marrow (this is where erythroid precursors have transferrin receptors). Measured as Iron Binding Capacity.
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What is the most abundant coag. factor (is also an acute phase reactant)- and how is it measured?
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Fibrinogen, it's measured by functional assay.
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Compare transudate to exudate.
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Transudate is body fluid that contains albumin and little protein. Exudate is an effusion (body fluid) much richer in protein, and has increased vascular permeability.
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What does the erythrocyte sedimentation rate measure?
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It's a nonspecific indicator of inflammation- the larger the increase of size of rbc's, the more severe the inflammation.
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In what diseases are high levels of Lactate Dehydrogenase detected?
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megaloblastic anemia, extensive neoplasia, severe shock, hypoxia (also wbc disorders, plumonary and MI- but not as high).
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What is a normal lab value for creatine kinase (CK)?
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55-170 micromol/L in M (less in F)
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What test results are consistent with hepatocellular damage?
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elevated AST and ALT, normal (or small incr.) in alkaline phosphatase, GGT, and 5'N
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What is a normal range for amylase?
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35-115 U/L
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What is a normal lab value for lipase, and what is it a marker for?
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36-239 U/L- pancreatic disease.
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