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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Platelets are derived from?
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Megakaryocytes
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Characteristic changes from Pronormoblast to Red Cell
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-loss of nucleus
-shrink in size -gain hemoglobin |
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At what stage are Red blood cells released into the bone marrow? normal %? characteristics?
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Reticulocytes - 1-2% in periph blood, residual RNA present
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what is wrong with this peripheral blood smear?
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increased reticulocytes (polychromatophils)
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RPI (reticulocyte production index) takes what values into account?
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reticulocyte %
hematocrite maturation time |
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RPI value for a production and a destruction issue
why this would occure? |
RPI<2 production issue
RPI>2 Destruction issue |
RPI<2: ineffective erythropoiesis, Fe deficiency, anemia
RPI>2: impaired hemolysis |
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The images represent bone marrow biopsies. What is different between the two?
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The right image displays an absence of sideroblasts- normoblasts with iron- due to anemia
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Normal or abnormal?
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Abnormal iron in a sideroblast- caused by lead/zinc poisoning, ethanol toxicity, INH treatment, copper or pyridoxine deficiency or MDS
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Why renal disease may lead to anemia
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decreased Epo production
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MCV definition
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Mean Cell Volume --> microcytic vs normocytic vs macrocytic anemia
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How to approximate Hematocrit?
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multiply Hb by 3
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MCH definition
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mean cell hemoglobin
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if a pt has low MCV and low MCH they are classified as having...
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microscopic hypochromic anemia
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normal MCV and normal MCH is classified as...
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normocytic normochromic anemia
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Classify the anemia:
Fe Deficiency |
microcytic hypochromic
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Classify the anemia:
anemia of chronic disease (ACD) |
Normocytic normochromic
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Classify the anemia:
Folate defieciency |
macrocytic anemia
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Classify the anemia:
Thalassemia |
Microcytic hypochromic
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Classify the anemia:
B12 deficiency |
Macrocytic anemia
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