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11 Cards in this Set
- Front
- Back
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Rb
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tumor sup
Rb, 13q, retinoblastoma and osteosarcoma, blocks G1-->S checkpoint |
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p53
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tumor sup
p53, 17p, Li-Fraumeni and lots of others, p53 phosphorylates Rb so can proceed |
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BRCA1
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tumor sup
BRCA1, 17q, breast/ovarian, DNA repair protein |
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BRCA2
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tumor sup
BRCA2, 13q, breast/ovarian, DNA repair protein |
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p16
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p16, 9p, melanoma
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APC
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tumor sup
APC, 5q, colon cancer (FAP) |
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WT1
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tumor sup
WT1, 11p, Wilm's |
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NF1
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tumor sup
NF1, 17q, NF Type 1 |
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NF2
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tumor sup
NF2, 22q, NF Type 2 |
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DPC
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tumor sup
DPC, 18q, pancreatic cancer "Deleted in Panc Cancer" |
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DCC
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tumor sup
DCC, 18q, colon "Deleted in Colon Cancer' |
