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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
define restrictive pulmonary disease
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reduced expansion of the lungs, reduction in total lung capacity
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name the 3 major categories of restrictive pulmonary causes
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bony abnormalities, neuromuscular disease, interstitial lung disease
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name at least 5 subtypes of interstitial lung disease
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ARDS, NRDS, pneumoconioses, sarcoidosis, idiopathic pulmonary fibrosis, SLE, scleroderma, Wegener granulomatosis
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what happens in ARDS and name 5 of 10 causes
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diffuse alveolar damage leads to protein rich fluid into alveoli, causes: shock, sepsis, trauma, uremia, gastric aspiration, acute pancreatitis, chlorine, oxygen toxicity, bleomycin, SARS
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what are the symptoms of NRDS
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dyspnea, cyanosis, tachypnea
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what type of cells secrete surfactant, what is surfactant made of
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type II pneumoctyes, lecithin dipalmitoyl
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what are the predisposing factors of NRDS, what are the associated complications
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prematurity, diabetes mellitus, cesarean section, bronchopulmonary dysplasia, patent ductus arteriousus, brain hemorrhage, necrotizing enterocolitis
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what are the 4 pneumoconioses
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anthracosis, coal workers pneumoconiosis, silicosis, asbestosis
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what is the offending dust particle in anthracosis and is it harmful
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carbon in urban areas, no harm
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what is the offending dust particle in coal workers pneumoconiosis, name the two types, name the pathological hallmark, and is it harmful
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"coal dust, simple and progressive massive fibrosis, coal macules around bronchioles for simple, fibrotic nodules with black fluid for progressive, simple is inconsequential, progressive can cause bronchiectasis and pulm hyper
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what is the offending particle in silicosis, name the 3 populations at risk, what the pathological hallmark is, and is it harmful
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silicone, miners, glass manufacturers, stone cutters, silicotic nodules, the nodules can eventually block the airway, increased susceptibility to TB
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which part of the lung does asbestos affect and how
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lower lobes, diffuse interstitial fibrosis
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what is the pathological hallmark of asbestosis
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ferruginous bodies (yellow brown rod with clubbed ends stain positive with prussian blue)
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what two cancers can asbestos cause
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bronchogenic cancer, malignant mesothelioma
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what is the pathology of sarcoidosis
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noncaseating granulomas
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what ethnic group and age does sarcoidosis effect
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african lineage and young adult
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name 3 symptoms and 2 lab abnormatlities of sarcoidosis
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bilateral hilar lymphadenopathy, interstitial lung disease, erythema nodosum, polyarthritis, hypercalcemia, hypercalciuria, increased serum angiotensin converting enzyme
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None
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name the morphological change invovled with eosinophilic granuloma and the syndrome its associated with
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birbeck granules (tennis racket), histiocytosis X syndrome
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Pulmonary hypertension: is primary or secondary more common, what is the most common cause of both
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secondary is more common, COPD causes secondary the most, primary is always idiopathic
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