Path - Random Facts For Exam 2

Front 1

HLA-DRB1

Back 1

Ulcerative Colitis

Front 2

SDK1 gene (autosomal dominant)

Back 2

Peutz Jegher's Polyp

Front 3

apc gene (5q21)

Back 3

FAP/Gardner's/Turcot

Front 4

CEA

Back 4

Tumor marker for colonic carcinoma

Front 5

MLH1, MLH2, MSH6, PMS genes

Back 5

HNPCC or sporadic right sided colonic carcinoma (due to microsatellite instability)

Front 6

AST / ALT > 2

Back 6

Alcoholic Liver Disease

Front 7

AST / ALT < 1

Back 7

Viral Hepatitis

Front 8

ALP

Back 8

Elevated in obstructive liver disease (cholestasis)

Front 9

GGT

Back 9

Elevated in cholestasis and alcohol use

Front 10

Serum albumin

Back 10

Decreased in chronic liver disease

Front 11

Prothrombin time

Back 11

Elevated in acute and chronic liver disease

Front 12

AFP (alpha-feto protein)

Back 12

Usually increased in HCC (hepatocellular carcinoma)

Front 13

Serum ammonia

Back 13

Increased in hepatic failure, HCC, Yolk sac tumors, Fetal neural tube defects, Fetal distress or death, Massive liver necrosis

Front 14

Ceruloplasmin

Back 14

Decreased in Wilson's disease

Front 15

HFE gene

Back 15

Hemochromatosis, chromosome 6

Front 16

Chromosome 13

Back 16

Chromosome for Wilson's Disease

Front 17

PiMM gene

Back 17

Gene for Alpha-1 Antitrypsin Deficiency, Chromosome 14, PiZZ is bad allele

Front 18

Anti-mitochondrial antibodies

Back 18

Primary Biliary Cirrhosis (90%)

Front 19

c-ANCA

Back 19

Wegener's Granulomatosis

Front 20

p-ANCA

Back 20

Churg-Strauss Syndrome and Microscopic Polyangitis

Front 21

anti-endothelium antibodies

Back 21

Kawasaki Syndrome

Front 22

anti-SMC antibodies

Back 22

Kawasaki Syndrome

Front 23

anti-platelet membrane glycprotein antibodies

Back 23

Immune Thrombocytopenia

Front 24

anti-Factor VIII antibodies

Back 24

Occurs in some people getting Factor VIII transfusions for hemophilia

Front 25

WT1 and PAX6 deletion

Back 25

WAGR Syndrome

Front 26

Trisomy 18

Back 26

Edwards Syndrome

Front 27

Trisomy 21

Back 27

Downs Syndrome

Front 28

Trisomy 13

Back 28

Patau Syndrome

Front 29

CD10+, CD19, CD20

Back 29

Follicular Lymphoma

Front 30

Follicular Lymphoma

Back 30

t(14:28)

Front 31

CD19, CD20, CD5, CD23, CD43

Back 31

SLL/CLL

Front 32

CD10+, CD19, CD20 and a surface Ig

Back 32

Burkitt's Lymphoma

Front 33

t(8:14) or t(2:8) or t(8:22)

Back 33

Burkitt's Lymphoma

Front 34

CD19, CD20, CD11c, CD25, CD103

Back 34

Hairy Cell Leukemia

Front 35

Plasma Cell Neoplasm of IgG

Back 35

Multiple Myeloma and Solitary Plasmacytoma

Front 36

Plasma Cell Neoplasm of IgM

Back 36

Waldenstrom's Macroglobinemia

Front 37

CD15+, CD30+, CD45-

Back 37

Classical Hodgkin's Lymphoma

Front 38

CD20+, CD45+, CD15-, CD30-

Back 38

Classical Variant Hodgkin's Lymphoma

Front 39

t(12:21)

Back 39

ALL in young patients (age 2-10)

Front 40

t(9:22)

Back 40

ALL in old patients (teen adult) or under 2 years old

Front 41

t(8:21)

Back 41

AML M2

Front 42

inv(16)

Back 42

AML M4

Front 43

t(15:17)

Back 43

AML M3

Front 44

CD13, CD33

Back 44

AML

Front 45

CD34

Back 45

Blast Marker for Acute Leukemia

Front 46

Abnormal Chromosome 5/7 or Trisomy 8

Back 46

Myelodysplastic Syndrome

Front 47

H inclusions

Back 47

Inclusions for Thalassemia

Front 48

Beta Globin genes

Back 48

Chromosome 11

Front 49

Alpha Globin Genes

Back 49

Chromosome 16

Front 50

Absence of CD55 and CD59 on WBCs

Back 50

PNH