Path: Myocardial, Pericardial And Endocardial Diseases

Front 1

clinical presentation of Myocarditis?

Back 1

many cases are asymptomatic

Acute = fever, pericarditis,EKG changes, dysarythmia, CHF. sudden death

Front 2

Characteristics of Viral myocarditis

Back 2

causes lymphocytic infiltrates with myocyte necrosis

elevation of Ab titers (Coxsacie B)

classic history inc. prior upper resp tract infection

Front 3

Characteristics of bacterial/ fungal myocarditis

Back 3

usually b/c of infective endocarditis os systemic infxn

Diptheric myocarditis = exotoxin produced by Corynebacterium diphtheriae

Front 4

Characteristics of protozoal myocarditis

Back 4

inc. thrichonosis, toxoplasms, and Chagas' disease

Dx made by demonstration of parasitization of individual myocardial fibers

Front 5

What is Chagas disease?

Back 5

cause of 25% of young adult deaths in endemic areas

flagellated trypanosomas circulate in blood, enter tissues and proliferate as amastigotes

fatality is due to acute phase of infection

Front 6

What is Toxoplasmosis?

Back 6

parasitic myocarditis most often seen in the presence of immunosuppression

Front 7

Characteristics of hypersensitivity myocarditis

Back 7

typically an allergic rxn to a drug (esp antibiotics)

peripheral eosinophilia is common; cardiac symptoms are usual

usually resolves when drug use ends and does not usually damage myocardium

Front 8

Characteristics of Autoimmune myocarditis

Back 8

may occur in systemic autoimmune disease

ex. lupus, scleroderma

Front 9

Characteristics of giant cell myocarditis

Back 9

not a single entity but may be seen as a part of any of the other myocarditis'

seen in granulomatous disease

Front 10

What are the 3 general groups of Cardiomyopathies?

Back 10

1. Dialted congestive cardiomyopathy

2. Restrictive Cardiomyopathy

3. Hypertrophic cardiomyopathy