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67 Cards in this Set

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S. aureus Protein A fxn
binds to Fc segment of Ig = inactivates complement cascade
S. aureus Coagulase fxn
coat bacteria with fibrin = inhibits opsonization and phagocytosis
Most common cause of Osteomyelitis and Endocarditis
S. aureus
common cause of UTI in young females
Staph saprophyticus
TSST-1
S. aureus
Scalded Skin Syndrome
Exfoliative toxins from S. aureus
Food poisoning 2-6 hrs. after a family reunion picnic
S. aureus = ingestion of Enterotoxin, not ingestion of organism
Carbuncles and Furuncles
S. aureus
Impetigo and Erysipelas
S. pyogenes
Gram + lancet shaped encapsultated microbe
Strep pneumo = pneumococcus
2 sequela of S. pneumo
Meningitis

Inner Ear infection
Leading cause of neonatal pneumonia, meningitis, and sepsis
Streptococcus agalactiae
Large, Gram + ROD that forms environmentally stable SPORES
B. anthracis
Most common type of Anthrax
Cutaneous = "malignant pustule"
Wool-sorter's disease = ?
Pulmonary anthrax = mediastinal widening
Mediastinal widening
Pulmonary Anthrax = good evidence of bio-terrorism
Unilateral Lymphadenopathy and Fever after a cat scratch
Bartonella Henselae = Cat Scratch fever
pseudo-membrane in the posterior pharynx, which can be aspirated and cause death from asphyxiation
Corynebacterium diphtheriae
conjunctivitis
pharyngeal membrane
bull neck
severe Myocarditis
C. diphtheria
What do you not give to person infected with Diphtheria?
Vaccine = makes myocarditis worse
Encapsulated Gram - cocco-bacillus that causes severe Upper RT infections, epiglottisis, otitis media, and meningitis

*mostly in children
H. influenza
Grows as satellite colonies next to S. aureus on blood agar
H. influenza
Whooping cough
Bordetella pertussis
can cause DIC and Water-House Friderichson Syndrome
N. meningitidis
cause of meningitis in college dorms and summer camps
N. meningitidis
toxin that ADP-ribosylates EF-2 thereby inhibiting protein synthesis
Diphtheria toxin
Describe H. influenza vaccine
Type b capsule conjugated with Diphtheria toxoid protein
Complememt deficiency (C5-C9) microbe
N. meningitidis
cause of Traveler's diarrhea
ETEC
-LT = increased cAMP
-ST = increased cGMP
causes child diarrhea in 3rd world countries due to malabsorption by adhering to and deforming intestinal villi
EPEC

**P = "preemie" = babies
E. coli clinically indistinguishable from Shigellosis
EIEC = bloody diarrhea
ETEC enterotoxin is similar to this toxin
Cholera toxin
associated with Hemolytic Uremic Syndrome
EHEC
Shiga toxin pathology
necrosis of epithelium -> A-B toxin -] 28S rRNA
"Enteric Fever" agent
Salmonella
Gall bladder is common reservoir for the enteric pathogen
Salmonella typhi
Microbe that has black colonies on Hektoen plates
Salmonella
Typhoid Fever
Salmonella
Rice-water stools
Cholera
Bloody diarrhea related to H. pylori that is transmitted by water, milk, and food
Campylobacter jejuni
Friedlander's pneumonia
Klebsiella
Encapsulated organism that causes pneumonia and may cavitate resembling TB
Klebsiella
Intracellular organism that needs to be treated with Marcolide that causes 5-lobe pneumonia
Legionella pneumonia

*treated with Macrolide b/c it's intracellular
grown on Charcoal Yeast Extract plates and stained with Dieterle silver stain
Legionella
Found around big buildings in water sources (condensors, AC)
Legionella
Found in standing water
Multidrug resistant
Common in CF patients
P. aeruginosa
Fruity odor colonies
P. aeruginosa
P. aeruginosa vasculitis
Ecthyema Gangrenosum
Pseudomembranous Colitis
C. difficile
Gas gangrene
C. perfringens
C. difficile infection is associated with this antibiotic use
Clindamycin
"Undulant Fever" infecting Macrophages/monocytes
Brucella
Brucella complications (2)
Osteomyelitis

Septic Arthritis
Non-caseating granuloma
Gram - coccobacilli
eating goat cheese
Brucella
found among rodents in desert SW and transmitted to humans by fleas
Yersinia pestis
Bubonic plague
Yersinia pestis
Rabbit Fever transmitted to humans by ticks
Tularemia
Lyme Disease agent
Borrelia Burgdorferi
Erythema Chronicum Migrans = "bull's eye rash"
Borrelia burgdorferi
Borrelia burgdorferi vector
Ioxodes tick
Jarisch-Herxheimer rxn
Borrelia burgdorferi
1. Rash
2. Meningo-encephalitis + Myopericarditis
3. Polyarthritis
Borrelia burgdorferi = Lyme Disease
Histopathologic lesion of Rickettsial infections
Typhus nodule =infection of endothelial cells
Where is RMSF most common
Appalachian mountains
Petechial rash appearing on palms and soles and moving centripally to trunk
RMSF
transmitted by Dermacentor tick
RMSF
Weil-Felix serological test may be diagnostic
RMSF