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67 Cards in this Set
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- Back
S. aureus Protein A fxn
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binds to Fc segment of Ig = inactivates complement cascade
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S. aureus Coagulase fxn
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coat bacteria with fibrin = inhibits opsonization and phagocytosis
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Most common cause of Osteomyelitis and Endocarditis
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S. aureus
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common cause of UTI in young females
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Staph saprophyticus
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TSST-1
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S. aureus
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Scalded Skin Syndrome
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Exfoliative toxins from S. aureus
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Food poisoning 2-6 hrs. after a family reunion picnic
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S. aureus = ingestion of Enterotoxin, not ingestion of organism
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Carbuncles and Furuncles
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S. aureus
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Impetigo and Erysipelas
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S. pyogenes
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Gram + lancet shaped encapsultated microbe
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Strep pneumo = pneumococcus
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2 sequela of S. pneumo
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Meningitis
Inner Ear infection |
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Leading cause of neonatal pneumonia, meningitis, and sepsis
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Streptococcus agalactiae
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Large, Gram + ROD that forms environmentally stable SPORES
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B. anthracis
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Most common type of Anthrax
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Cutaneous = "malignant pustule"
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Wool-sorter's disease = ?
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Pulmonary anthrax = mediastinal widening
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Mediastinal widening
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Pulmonary Anthrax = good evidence of bio-terrorism
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Unilateral Lymphadenopathy and Fever after a cat scratch
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Bartonella Henselae = Cat Scratch fever
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pseudo-membrane in the posterior pharynx, which can be aspirated and cause death from asphyxiation
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Corynebacterium diphtheriae
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conjunctivitis
pharyngeal membrane bull neck severe Myocarditis |
C. diphtheria
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What do you not give to person infected with Diphtheria?
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Vaccine = makes myocarditis worse
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Encapsulated Gram - cocco-bacillus that causes severe Upper RT infections, epiglottisis, otitis media, and meningitis
*mostly in children |
H. influenza
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Grows as satellite colonies next to S. aureus on blood agar
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H. influenza
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Whooping cough
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Bordetella pertussis
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can cause DIC and Water-House Friderichson Syndrome
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N. meningitidis
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cause of meningitis in college dorms and summer camps
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N. meningitidis
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toxin that ADP-ribosylates EF-2 thereby inhibiting protein synthesis
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Diphtheria toxin
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Describe H. influenza vaccine
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Type b capsule conjugated with Diphtheria toxoid protein
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Complememt deficiency (C5-C9) microbe
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N. meningitidis
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cause of Traveler's diarrhea
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ETEC
-LT = increased cAMP -ST = increased cGMP |
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causes child diarrhea in 3rd world countries due to malabsorption by adhering to and deforming intestinal villi
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EPEC
**P = "preemie" = babies |
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E. coli clinically indistinguishable from Shigellosis
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EIEC = bloody diarrhea
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ETEC enterotoxin is similar to this toxin
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Cholera toxin
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associated with Hemolytic Uremic Syndrome
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EHEC
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Shiga toxin pathology
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necrosis of epithelium -> A-B toxin -] 28S rRNA
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"Enteric Fever" agent
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Salmonella
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Gall bladder is common reservoir for the enteric pathogen
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Salmonella typhi
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Microbe that has black colonies on Hektoen plates
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Salmonella
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Typhoid Fever
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Salmonella
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Rice-water stools
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Cholera
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Bloody diarrhea related to H. pylori that is transmitted by water, milk, and food
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Campylobacter jejuni
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Friedlander's pneumonia
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Klebsiella
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Encapsulated organism that causes pneumonia and may cavitate resembling TB
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Klebsiella
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Intracellular organism that needs to be treated with Marcolide that causes 5-lobe pneumonia
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Legionella pneumonia
*treated with Macrolide b/c it's intracellular |
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grown on Charcoal Yeast Extract plates and stained with Dieterle silver stain
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Legionella
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Found around big buildings in water sources (condensors, AC)
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Legionella
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Found in standing water
Multidrug resistant Common in CF patients |
P. aeruginosa
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Fruity odor colonies
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P. aeruginosa
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P. aeruginosa vasculitis
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Ecthyema Gangrenosum
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Pseudomembranous Colitis
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C. difficile
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Gas gangrene
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C. perfringens
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C. difficile infection is associated with this antibiotic use
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Clindamycin
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"Undulant Fever" infecting Macrophages/monocytes
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Brucella
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Brucella complications (2)
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Osteomyelitis
Septic Arthritis |
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Non-caseating granuloma
Gram - coccobacilli eating goat cheese |
Brucella
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found among rodents in desert SW and transmitted to humans by fleas
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Yersinia pestis
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Bubonic plague
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Yersinia pestis
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Rabbit Fever transmitted to humans by ticks
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Tularemia
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Lyme Disease agent
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Borrelia Burgdorferi
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Erythema Chronicum Migrans = "bull's eye rash"
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Borrelia burgdorferi
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Borrelia burgdorferi vector
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Ioxodes tick
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Jarisch-Herxheimer rxn
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Borrelia burgdorferi
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1. Rash
2. Meningo-encephalitis + Myopericarditis 3. Polyarthritis |
Borrelia burgdorferi = Lyme Disease
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Histopathologic lesion of Rickettsial infections
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Typhus nodule =infection of endothelial cells
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Where is RMSF most common
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Appalachian mountains
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Petechial rash appearing on palms and soles and moving centripally to trunk
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RMSF
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transmitted by Dermacentor tick
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RMSF
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Weil-Felix serological test may be diagnostic
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RMSF
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