Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
67 Cards in this Set
- Front
- Back
|
Foreign body granulomatous reaction to lipid of meibomian glands or Zeis glands
|
Chalazion
|
|
|
What is considered the "foreign body" in Chalazion
|
lipid excreted from meibomian/zeis glands
|
|
|
Chalazion: histology
|
granuloma, giant cells, lymphocytes, plamsa cells and PMNS
|
|
|
waxy, raised nodules with umbilicated center
|
Moluscum contagiosum
|
|
|
soft, yellowish plaques on medial aspect of eyelids
|
xanthelasma
|
|
|
xanthelasma: association
|
hyperlipidemia
|
|
|
xanthelasma: histology
|
foamy cells in superficial dermis
|
|
|
Touton giant cells
|
Juvenile xanthogranuloma
|
|
|
yellow-orange skin nodules in children
|
Juvenile xanthogranuloma
|
|
|
why are the lesions in Juvenile xanthogranuloma yellow
|
vascular
|
|
|
spontaneous, non-traumatic hyphema (blood in anterior chamber) in children
|
Juvenile xanthogranuloma
|
|
|
T/F: most nevi of the eyelids are congenital
|
F: most are acquired
|
|
|
MC malignant tumor of the eyelid
|
BCC
|
|
|
Where does BCC appear with respect to the eyelid
|
Lower>medial>upper
|
|
|
raised, firm nodule with "pearly" borders on upper eyelid
|
BCC
|
|
|
Nodular BCC histology
|
nests and cords of proliferating epidermal basal cells
|
|
|
T/F BCC mets to lung
|
false, it is rare for BCC to met
|
|
|
BCC: tx
|
complete resection
|
|
|
carcinoma that mimics chalazium
|
sebaceous carcinoma
|
|
|
Sebaceous carcinoma: who
|
elderly
|
|
|
Sebaceous carcinoma: where
|
meibomian, zeis or glands associated with caruncle
|
|
|
tumor of zeis glands that grows in nests with central necrosis. May be solid or papillary
|
sebaceous carcinoma
|
|
|
fungating mass on eyelid with keratin on surface
|
SCC
|
|
|
T/F: SCC mets to lymph nodes
|
T
|
|
|
only disease of the conjunctiva
|
benign ocular cicatricial pemphigoid
|
|
|
benign ocular cicatricial pemphigoid: who
|
elderly
|
|
|
adhesions (symblepharon), entropion(eyelid turned inward), trichiasis, corneal scarring
|
benign ocular cicatricial pemphigoid
|
|
|
5 layers of the cornea
|
epithelium, bowman's, stroma, descements, endothelium
|
|
|
embryologic origin of cornea
|
neural crest
|
|
|
cause of corneal edema
|
loss of endothelial cells
|
|
|
The number of endothelial cells in the cornea decreases with …
|
age
|
|
|
who is most suceptible to corneal infection
|
those who wear contact lenses and don't use sterile solutions
|
|
|
inflammation of cornea
|
acanthamoeba keratitis
|
|
|
star-shaped cyst, ring infiltrate, not a lot of inflammatory cells
|
acanthamoeba keratitis
|
|
|
4MC indications for corneal transplant
|
aphakic/pseudophakic bullous keratopathy, Fuchs dystrophy, keratoconus and graft failure
|
|
|
55yo female with cloudy cornea and corneal edema
|
fuchs endothelial dystophy
|
|
|
guttata, thickened Descement's membrane, loss of endothelial cells
|
fuchs endothelial dystophy
|
|
|
Keratoconus may be associated with…
|
atopy, Downs, Marfans
|
|
|
bilateral central ectasia of cornea that produces myopia and irregular astigmatism
|
keratoconus
|
|
|
keratoconus: early histo changes
|
breaks in epitheliam BM and Bowmans, central stromal thinning, anterior stromal scarring
|
|
|
fleisher ring
|
keratoconus
|
|
|
munson's sign
|
keratoconus
|
|
|
Intraocular neuroblastic tumor
|
retinoblastoma
|
|
|
Intraocular melanocytic tumor
|
malignant melanoma of the uvea
|
|
|
MC tumor to eye
|
mets (esp to choroid) from BC,lung, leukemia
|
|
|
MC intraocular malignancy of childhood
|
retinoblastoma
|
|
|
retinoblastoma: uni or bilateral
|
33% bilateral
|
|
|
Leukocoria
|
retinoblastoma
|
|
|
retinoblastoma: gene
|
chromosome13 tumor suppressor
|
|
|
round, oval or spindle-shaped nuclei; hyperchromatic, necrosis, calcification, Flexner-Wintersteiner rosettes
|
retinoblastoma
|
|
|
Homer Wright rosettes
|
retinoblastoma, neuroblastoma or medulloblastoma
|
|
|
what's in the lumen of homer wright rosettes
|
eosinophilic cytoplasm
|
|
|
Most important risk/prognostic factor for retinoblastoma
|
extraocular extension
|
|
|
MC primary intraocular tumor of adults
|
malignant melanoma of the uvea
|
|
|
melanoma of the uvea: who
|
53yo blue-eyed Europeans
|
|
|
melanoma of the uvea: MC location
|
choroids
|
|
|
melanoma of the uvea: clinical presentation
|
visual loss, glaucoma, inflammatory signs mimicking endophthalmitis
|
|
|
melanoma of the uvea: prognostic factors
|
size
cell type |
|
|
melanoma of the uvea: cell types
|
spindle cell
epithelioid cell mixed cell |
|
|
Do melanomas of the uvea met via lymphatic or hematogenous spread
|
hematogenous to liver. the uvea and orbit lack lymphatics.
|
|
|
MC primary malignant orbital tumor of childhood
|
rhabdomyosarcoma
|
|
|
sudden proptosis in medial, inferior or posterior quadrant
|
rhabdomyosarcoma
|
|
|
rhabdomyosarcoma: 3 histologic growth patterns
|
embryonal(most common)
alveolar differentiated |
|
|
spindle cells are arranged ina loose syncytium with occasional cells bearing cross-striations; desmin+
|
rhabdomyosarcoma
|
|
|
rhabdomyosarcoma: 5yr survival
|
92%
|
|
|
Optic nerve atrophy: etiology
|
ascending atrophy: loss of retinal ganlion cells b/c of glaucoma/infarction
descending: pathology in cranial cavity or orbit |
|
|
large cystic spaces containing mucopolysaccharide material posterior to lamina cribrosa
|
cavernous optic atrophy of schnabel
|
