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20 Cards in this Set

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Aortic Aneurysms
Abdominal aortic aneurysm
Syphilitic Aneurysim
AAA-below renal above iliac arteries
up to 15 cm diametes
inflammatory or mycotic
can rupture, obstruct, embolize, impinge, or present as mass

syphilitic-tertiary syphilis
obliterate vasa vasorum, cause ischemia->scarring->loss of elastic fibers->aneurysm
scars=tree baring
damage from aortic valve ring dilation
Aortic Dissection
Type A-from ascending aorta
Type B-not including ascending aorta
tear usually within 10 cm of aortic valve
can create double-barreled lumen
Marfan syndrome pre-exsiting
Giant Cell vasculitis
Most common
granulomatous inflammation of large to small arteries
affect arteries of the head, especially temporal
patients over 50 with pain, diplopia, visual loss
Takayasu Arteritis
Pulseless disease
granulomatous inflammation of aortic arch and branches
decreased pulse in upper extremitites
women under 40, high incidence in japan
polyarteritis nodosa
small/medium muscular arteries
30% have hep B
segmental transmural necrotizing inflammation with fibrinoid necrosis
young adults 90% remission with steoirds/cyclophosphamide
Kawasaki Disease
characteristic involvement of coronary arteries
affect large to small arteries
80% under 4 yrs and endemic to japan
only 20% develop CV sequelae
Microscopic Polyangiitis
broken down leukocytes affecting arterioles, capillaries and venules
P-ANCA in 70%
90% have necrotizing glomerulonephritis
all lesions same age unlike PAN
Churg-Strauss syndrome
necrotixing vasculitis with granuloma and association with allergic rhinitis and bronchial asthma.
P-ANCA
Wegener Granulomatosis
Necrotizing arteritits, renal disease, granuloma of respiratory tract
C-ANCA in 95%
Thromboangiitis Obliterans
smokers with thrombosing acute and chronic inflammation of tibila and radial arteries
less than 35 yrs
genetic component related to tobacco use
Raynaud phenomenon
red/white/blue of fingers and toes when exposed to the cold
mean age 14 mainly in females
can be secondary from other disease
varicose veins
abnormally dilated tortuous veins
over 50 yrs obesity, women, familial involvement, stand on legs for long periods
no association with embolism
other sites: esophageal varices, hemorrhoids
thrombophlebitits/phlebothrombosis
inflammation and thrmbosis of deep leg vein
associated with cardiac failure, pregnancy, obesity, post operative, prolonged bed rest
pulmonary emboli common and serious complication
superior/inferior vena caval syndrome
carcinoma or lymphoma compressing or infiltrating the vena cava
Hemangioma
localized benign tumor, most commonly affect skin in head and neck
lymphangioma simple
capillary benign tumor, if cavernous=turner syndrome
glomus tumor
benign tumor of smooth muscle cells of distal digits composed of blood vessel and glomus cells
painful lesion
bacillary angiomatosis
opportunistic infection of immunocompromised
red subQ nodules
Kaposi Sarcoma
Chronic-individual of eastern European or Mediterranean descent with red to purple nodules on arms or legs

Lymphadenopathic, african-south african bantu children, aggressive

Transplant/immunosuppressed-lymph nodes, mucosa, visceral organs, aggressive unless degress immunosuppression

AIDS-involves lymph nodes, gut

human herpesvirus-8 in 95% of lesions
cloassic disease of skin with patches of plaques or nodules over time
Angiosarcoma
malignant neoplasm of endothelial cells, in older adults and involves skin, soft tissue, breast or liver

can be hepatic if exposed to arsenic, thorotrast, PVC
lymphedema and radiation can also cause it

can be well differentiated to poorly differentiated

poor prognosis with low 5 yr survival