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50 Cards in this Set
- Front
- Back
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What ovarian disease involves psammoma bodies
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Serocystadenocarcinoma
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PKU deficiency
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Phenylalanine hydroxylase
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Which form of emphysema is associated with alpha-1-antitrypsin deficiency
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Panacinar
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Most common lobes affected in herpes encephalitis
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Temporal lobes
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What is the term for the appearance of the kidney in malignant HTN
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Flea-bitten kidney (also seen in pyelonephritis) – has petechiae on it’s surface
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What organ must metastasize for carcinoid heart disease to occur
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Liver
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Most common circulating Ig in plasma
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IgG
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What is the tetralogy of fallot?
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VSD, RVH, overriding aorta, and pulmonary stenosis
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Call-Exner bodies
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Granulosa/thecal cell tumor of the ovary
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What gene inhibits apoptosis by preventing the release of cytochrome c from the mitochondria
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Bcl-2
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Multiple schwannomas, café au lait spots, Lisch nodules, chromosome 17q
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Neurofibromatosis I (Neurofibromatosis II is chrom 22q with no Lisch nodules)
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Most common Renal cell cancer type
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Clear cell
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Most common cause of UTI
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E coli
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What pancreatic islet cell tumor is associated with hyperglycemia, sweating, hunger, confusion, and icreased C-peptide levels?
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Insulinoma
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What AD GI neoplasia produces multiple adenomatous polyps, osteomas, fibromas, and epidural inclusion cysts
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Gardner syndrome
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Hep virus that is an enveloped RNA flavivirus
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Hep C
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Cancer associated with erb-1
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Squamous cell carcinoma of the lung
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What stromal tumor in males is characterized histologically with crystalloids of Reinke
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Leydig cell tumor
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Most common cause of hypothyroidism in US
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Iatrogenic
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Most common cause of endocarditis following biliary infections
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Enterococcus faecalis
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Renal epithelial casts in the urine
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Acute toxic or viral nephrosis
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What 3 LTs are associated with bronchospasms and an increase in vessel permeability and vasoconstriction
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LC4, LD4, LE4
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Term for raised fluid filled cavity up to 0.5 cm that lies between layers of the skin
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Vesicle
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Most common Brain tumor
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Metastatic
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Which intergrin mediates adhesion by binding to lymphocyte function associated Ag 1 (LFA-1) and MAC-1 leukocyte receptors
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Intercellular adhesion molecule (ICAM) 1
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3 enzymes that protect the cell from oxygen derived free radicals
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SOD, Glutathione peroxidase, catalase
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What component of the basement membrane binds to collagen type IV and hep sulfate and is a cell surface receptor
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Laminin
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Most common CNS infection in AIDS
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Toxoplasmosis
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Most common Benign breast tumor in females under 35
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Fibroadenoma
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What lymphoma is associated with bleeding and cryoglobulin precipitation at low temperatures, headache and confusion due to hyperviscosity, IgM M-protein spike on electrophoresis and Russell bodies
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Waldenstrom’s macroglobulinemia
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What CNS developmental abnormality is assoc with 90% of syringomyelia
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Arnold Chiari malformation type 2
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Notching of the ribs, seen on CXR in pts with postductal coarctation of the aorta is due to collaterization of what arteries?
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Dilation of internal mammary arteries
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The 4 DNA oncogenic viruses
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HPV, EBV, Hep B, Kaposi sarcoma
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Glycogen storage disease due to deficiency of muscle phosphorylase
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McArdle’s syndrome
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Average volume of RBC
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MCV
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Cancer associated with sis
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Astrocytoma
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Most common location of gastric ulcer
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Lesser curvature of the antrum
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4 causes of hypochromatic microcytic anemia with low MCV
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Sideroblastic anemias (porphyrin and heme synthesis disorders), Thalassemia, Iron deficiency, Lead poisoning
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What AD disorder due to a mutation in fibroblast growth factor receptor 3 results in normal-size vertebral column and skull and short, thick extremities
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Achondroplasia
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Most common Complement deficiency
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C2 deficiency
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What is the tumor at the bifurcation of the right and left hepatic ducts
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Klatskin tumor
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Most common colonic diverticula
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Sigmoid colon
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What cell type involves humoral immunity
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B lymphocyte
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Deletion to maternal chromosome 15 results in
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Angelman syndrome
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What rapidly progressive and aggressive T-cell lymphoma affects young males with a mediastinal mass (thymic)
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Lymphoblastic lymphoma
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Neurofibromatosis Type I associated chromosome
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Chromosome 17
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What are the 3 main components of amyloid
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Fibrillary protein, amyloid protein, and glycosaminoglycans (mostly hep sulfate)
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Painless hyperemic lesions on palms and soles associated with bacterial endocarditis
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Janeway lesions
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What form of hemophilia is x-linked recessive and is due to a deficiency in factor 9
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Hemophilia B
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Cancer associated with vinyl chloride
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Angiosarcoma of the liver
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