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8 Cards in this Set

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Hyperplasia
Increased number of cells due to increased stimulation by hormones or growth factors
Hypertrophy
Hypertrophy is increased size of cells.
What determines whether a cell undergoes hyperplasia or hypertrophy?
Whether cells will undergo hyperplasia or hypertrophy depends on their regenerative capacity. Some cells can replicate and therefore undergo hyperplasia. Others such as cardiac muscle cells have limited replicative ability and respond to increased work load by increasing their size. Often both happen simultaneously such as during pregnancy.
Atrophy
Diminution in the size of the cell
Pathologic Adaptation
Occurs when it is evidence of a response to a harmful or potentially harmful stimulus.
Physiologic Adaptation
Occurs in response to normal stress.
What seven stimuli induce atrophy?
Decreased workload, loss of innervation, diminished blood supply, inadequate nutrition, loss of endocrine stimulation, aging, pressure
Metaplasia
Response to chronic irritation, whereby one adult cell type is replaced by another. Typicall occurs in epithelial tissues including the distal end of the esophagus.