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13 Cards in this Set
- Front
- Back
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pediatric disease following Strep infection
involved heart, joints, CNS |
Strep. pyogenes
group A B-hemolytic (pharyngitis [strep throat]) |
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Abnormal host immune response for rheumatic infection
is associated with which molecule? |
HLA class II
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Early Acute phase of rheumatic fever
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nonspecific myocarditis
fibirnoid degeneration of collagen |
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A ring of fibrous tissue from which leaflets arise. helps electrically insulate atria from ventricles
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anulus
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Atrioventricular valves (mitral/tricusp) have 5 components
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Anulus
Leaflets Commissures Chordae tendinae Papillary muscles |
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Semilunar valves (pulm/aortic) have 3 components
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Anulus
Cusps Commissures |
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What comprises the valvular apparatus in Atrioventircular valves?
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Annulus
Leaflets Commissures |
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What comprises tensor apparatus in the atrioventricular valves?
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chordae tendineae
papillary muscles |
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perivascular swollen collagen with lymphs, macs and plasma cells
--> granulomatous with Giant Cells (macrophages) w/ Fibrinoid center and surrounding inflammation |
Aschoff Body
Rheumatic Fever |
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pathgnomic feature of rheumatic fever
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aschoff body
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pt. present w/ all 4 leaflets inflamed. leads to loss of endothelium and deposits of fibrin nodules that look like verrucae (warts).
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endocarditis --> Rheumatic Fever
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Diagnose criteria for Rheumatic Fever
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JONES criteria
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serum levels show
Antistreptolysin O anti-hyuluroniase anti-DNase B |
S. pyogenes
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