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19 Cards in this Set

  • Front
  • Back
Pasteurella and Mannheimia general characteristic
Gram negative rods
facultative anaerobe
non motile
non-spore forming
Pasteurella and Mannheimia spp. Natural habitat
Commensals of the oropharyngeal and gastrointestinal tract mucosa
mammals, birds, and reptiles, survives poorly outside the host
Pasteurella and Mannheimia Respiratory ssp
M haemolytica
P. motocida
B trehalosi
Pasteurella and Mannheimia Respiratory pathogenesis
decreased host defenses allow commensal bacteria livingi nt he upper respiratory tract to infect the lungs
Pasteurella and Mannheimia Septicemia ssp.
P. multocida
B. trehalosi
Pasteurella and Mannheimia Septicemia ssp. pathogenesis
Fowl cholera, Haemorrhagic septicaeimia, vascular compromis and disruption
Pasteurella and Mannheimia Trauma ssp.
P. multocida
P. aerogenes
P. canis
Pasteurella and Mannheimia pathogenesis
Bites, scratches, licking
Pasteurella gallinarum
Fowl cholera (avian cholera)
Pasteurella multocida diseases
Atrophic rhinitis
Pneumonia in ruminants
Snuffles in rabbits
pasteurella multocida ssp serogroups
A, B, D, E, F based on hemagglutination of capsular antigens, eleven serotypes based on host specificity and pathogenicity
Pasteurella multocida serotypes
B:2 (asia)
E:2 ( Africa)
Haemorrhagic septicaemia via Pasteurella multocida
not present in USA
Pasteurella spp virulence factors
Capsule
different capsular serotypes
fimbria
reduces the antigenicity of the capsule
LPS
Pasteurella endotoxin
LPS
toxic to respiratory epithelium
decreases phagocytosis
elictis inflammatory reaction
P. multocida toxin
capsule type D
osteolytic
inhabits mucous membranes of the upper respiratory tract
Mannheimia spp virulence factors
leukotoxin, LPS - together drive a tissue destroying inflammatory response
Capsule, Fibriae, Adh1, Fibrinogen, exotoxins
Bovine respiratory disease complex
bronchopneuomina, fibrinous pleuropneumonia via Mannehemia haemolytica, Pasteurella multocida, inhalation, ingestion, direct inoculation,
Pasteurella and mannheimia spp public health significance
P. multocida from bite wounds.