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30 Cards in this Set

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InActivate Na+ chnl
"PVC"
Phenytoin
Valproate
Carbamazepine
Osteomalacia
Phenobarbital and Phenytoin
Induce CYP450
Inc Metab of Vit D/K
Dec Abs Ca (bone resorp)
Baclofen
GABAb-R link to K chnl
Hyperpol
Prvnt release Glut onto a-motor neurons
Dantrolene
Trt Malig Hyperthermia
Trt Neuroleptic Malig Synd
NE Reuptake blocked
Desipramine
5-HT Reuptake blocked
SSRIs
Fluox, Fluvox
Parox, Citalopram
Both NE/5HT blocked
Imipramine
Clomipramine
Venlafaxine
MAOI
Phenel&Trany
No Tyramine foods
Inhib MAO-A (so NE&5HT stay arnd)
AntiPsycho
Block D2-R in Mesolimbic
Haloperidol=least sedate (turrets)
Clozapine= Trt Neg Symp
Chlorpromazine= Prevent N/V
Lithium
ReAbs Inc by HCTZ/Furosemide
Nephrogenic DI
If 1st Trimester=Ebsteins (mitral/tricuspid problem)
Parkinsons
L-Dopa= precursor to DA
Carbidopa= inhib decarbox
can dec amnt of dopa)
Benztropine= Cent Musc block
Amantadine=Antiviral release DA
Selegiline=MAO-B inhib
Cause HyperPRL
Haloperidol
Reserpine
Metoclopramide
a-Methyldopa
Inhib PRL relase=Bromocrip
Ethanol removal
First=Zero Order (amnt)
Later=First Order (frac)
Methanol Tox
Like in snow storm
Phentermine
Dec Appetite
Bc release NE in Hypothal
Thiopental
Poor analgesic
Induction of Anesthesia
Shrt duration bc Redeistrib
BZ
Old ppl: Inc halflife
Dec Cl
Dec P450
Dec plasma prot
Inc R-sens (Inc falls)
Glucuronidation
No dec in old ppl
So use:
Oxazepam, Lorazepam
Flumazenil
BZ-R Antag
Trt BZ OD
(also precip withdrawl)
Buspirone
Anxiolytic (no addict)
Part Ag @ 5-HT1a
Slow onset
Naloxone
iv
For Opiate OD (resp depress)
Need Mult Doses
(Naltrexone=po)
Partial mu Agonists
Pentazocine
Butorphanol
Nalbuphine
buprenorphine
Get withdrawl/less respir dep
No Tolerance w/Opiates
Constipation
Miosis
Diphenoxylate
Least addictive
Trt Diarrhea
MAC
MAC high=o/g low=potency low
DOESNT affect rate of induction
b/g coeffic
b/g low=poor sol=rapid on/off
Anemics: quicker on/off
(less RBC- Sat quicker)
Nitrous Oxide
secondary gas
Pulls Halothane along
Quickens onset/offset
Diffusional Hypoxemia
Rupture TM of N/V after surg
Ketamine
block NMDA glut-R
Dissoc State/PostAnesth halluc
Least respir suppress
Etomidate
Inc GABAa-med Cl-conduc
Hyperpol
Min effect BP/Respir
Myoclonic so Pretrt w/BZ
BP/Respir
Opiate= Dec respir
Ketamine= Inc BP
Etomidate= nothing
Thiopental= Dec BP/Respir