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19 Cards in this Set
- Front
- Back
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levodopa |
crosses BBB prodrug synthesized to DA by DDC in periphery |
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carbidopa |
does NOT cross BBB inhibits DDC |
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COMT inhibitors |
tolcapone entacapone stalevo (carbidopa + levodopa + entacapone) |
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non ergot dopamine agonists |
pramipexole ropinirole apomorphine rotigotine
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ergot dopamine agonists |
bromocriptine |
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MAO-B inhibitors |
selegiline rasagiline |
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M1 receptor blockers |
trihexylphenidyl benztropine |
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multifactorial PD drug |
amantadine |
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Rx for essential tremor |
propranolol (B-blocker) AEDs (primidone, gabapentin, clonazepam) alprazolam |
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GABAb agonist for dystonia |
baclofen |
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decreases calcium release from SR |
dantrolene |
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Ca channel blockers |
verapamil diltiazem |
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neurotoxin used for dystonia and spasticity |
botulinum toxin A and B |
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centrally acting α2-adrenergic agonist, reduces spasticity by increasing presynaptic inhibition of motor neurons |
tizanidine |
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Rx for chorea in HD |
Neuroleptics (ex. haloperidol) dopamine depleting agents (tetrabenazine); benzodiazipines
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AChE inhibitors for AD |
donepezil (Aricept), rivastigmine (Exelon), galantamine (Razadyne) |
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NMDA receptor agonist for AD |
memantine |
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ALS Rx |
riluzole blocks TTX sensitive Na channels associated w/ damaged neurons |
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MS Rx |
INFB and noninterferon immunomodulators |
