Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Dopamine precursor (L-dopa) with a peripheral dopamine decarboxylase inhibitor (Carbidopa).
|
L-Dopa with Carbidopa/Sinemet
|
|
|
What are the side effects of Sinemet?
|
Prior to addition of Carbidopa, nausea was the most frequent side effect experienced by patients taking L-dopa. While nausea may still occur when Carbidopa is added to L-dopa, this side effect has been significantly reduced. Hallucinans, nightmares, dyskinesia (uncontrolled movement) and serpentine like movement (chorea). Unfortunately, unresponsiveness to the drug is inevitable.
|
|
|
Mimics dopamine in stimulation of dopamine receptor sites.
|
Bromocriptine/Parlodel
|
|
|
What are the side effects of Bromocriptine?
|
nausea, hypotension, confusion, hallucinations, headache, depression, dyskinesia, and possible seizures.
|
|
|
Anticholinergic antagonist at muscarinic receptor sites.
|
Benztropine/Cogentin
|
|
|
What are the side effects of Cogentin?
|
Dry mouth, blurred vision, urinary retention, constipation, confusion, drowsiness, disorientation, memory impairment, visual hallucinations and possible exacerbation of pre-existing psychotic symptoms.
|
|
|
Antagonism of NMDA appears to result in diminished dopamine reuptake which may be the chief mechanism that accounts for
|
Amadatine/Symmetrel
|
|
|
What are the side effects of Amantadine?
|
Light headedness, confusion, drowsiness, nightmares, dry mouth, constipation, urinary retention, nausea and vomiting.
|
|
|
The order of efficacy of the medications used to treat Parkinson's disease
|
L-dopa>Bromocriptine>Amantadine>anticholinergics
|
