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15 Cards in this Set
- Front
- Back
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Parkinsons drugs |
Little dopamine and too much acetylcholine Postural instability Tremors Rigidity Shuffling Gait Meds dont cure they only manage |
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Dopamine replacement drugs |
Levadopa Carbidopa |
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Carbidopa |
Allows to cross the blood brain barrier |
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Levadopa |
Only effective 5-10 years Beta 1 stimulation= CVD cautions |
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Levadopa/ Carbidopa Adverse Effects |
Urine, sweat and saliva dark red/brown Psychosis Visual hallucinations Dizziness Drowsiness Ataxia Dyskenesthia Orthostatic hypotension |
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Bromocriptine, Ropinrole, pramipexole |
Stimulate dopamine receptors 1st line supplements to levadopa |
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Anticholinergic (benzotropine) |
Decrease muscle rigidity and tremmors Anti-cholinergic effects Extrapyramidal symptoms |
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Antihistamines for parkinsons |
Diphenhydramine |
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COMT inhibitors |
Break down and prolong levadopa Entacapone |
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Entacapone cautions |
Liver disease |
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Entacapone Adverse effects |
Dark orange urine, drowsiness, dizziness, ataxia, orthostatic hypotension, diskenesthia |
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MAO-B inhibitor |
Breaks down acetylcholine and increase dopamine stimulations Selegiline |
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Selegiline |
50-60% effective Prolongs 9-18 years <10mg |
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Amantadine |
Release dopamine in brain where it is stored Anti cholinergic effects Only effective 6-12 months Skin discoloration |
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Patient Teaching for Parkinsons drugs |
Drink water Not a cure Dont stop taking it |
