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11 Cards in this Set

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Shy Dragger syndrome?


Parkinson's disease + Orthostatic

Diagnostic test of Parkinson's?

No diagnostic test


Only clinical ( Bradykinesia plus one other symptom)

Treatment for Parkinson's (imp)

Mild <60yr (Benzotropine)


>60yr: 1. Amentadine (Inc Ach)


Severe disease: levopoda+ carbidopa


Ropinerole or Pramipexole ( dopamine agonist)


*Bromocriptine has more side effects


Symptoms after above drugs: add tolcapone/ entacapone (comt inhib)


Selegiline: can be use alone or with others.

Side effects of leodopa+carbi

On/off phenomenon

Ropinerole / Pramipexole

Less side effects


But less potent


(That's why levopoda is use)

Parkinsonism

Parkinson's symptoms

Tremors ( resting, pillrolling tremors)


Rigidity (cog wheel, lead pipe)


Akinesia (Bradykinesia)


Postural (stopped posture, problem with balance)

TRAP

Deep brain stimulation

Summary

Benign Essential tremor?

Both resting and intention tremors


Treatment: Propanol


Get worse with caffeine, Beta agonist

Restless leg syndrome?

Discomfort to control legs at night


Treatment: Ropinerole/Pramipexole