Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
3 Cards in this Set
- Front
- Back
|
Levodopa
(L-Dopa) |
precursor to the neurotransmitters dopamine.
passes the BBB. counteracts deficiency of Dopamine in the basal gng. (=parkinson). SidEf- involuntary movement, on-off effect, nausea, anxiety, postural HypoTens & psychotic symptoms. |
|
|
Carbidopa
|
given together with L-Dopa.
doesn't pass the BBB. inhibits peripheral metabolism of levodopa and its effect on the periphery and increases the L-Dopa t1\2. |
|
|
Entacapone
|
A COMT inhibitor.
increases the t1\2 of dopamine (inhibits dopamine metabolism. SidEf- involuntary movements. |
