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13 Cards in this Set
- Front
- Back
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Lab values for Familial Hypercalcemic Hypocalciuria?
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High Ca
Normal PTH Low 24 hour urinary Ca |
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How do FHH values differ from HyperPTH?
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HyperPTH would have normal or high 24 hour Urinary Ca
(and probably not normal PTH) |
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Causes of Non-PTH Hypercalcemia?
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Granulomas
Thyrotoxicosis Meds Vit D Intoxication Calcium Consumption |
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So as far as "most's" go, what's up w/ hypercalcemia and Primary HyperPTH vs Malignancy?
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Primary HyperPTH is the most common cause of hypercalcemia overall
BUT malignancy is the most common cause of hypercalcemia that leads to hospitalization, i.e. if you're in the hospital and you have hypercalcemia, then look for malignancy |
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Types of Primary HyperPTH?
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Ademoa
Multiple Gland Hyperplasia |
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Course of Primary HyperPTH?
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BIPHASIC
a) short period of progression b) long period of stability (not always super high, but can get reset at a higher than normal level) |
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Indications for surgery for hyperPTH?
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Serum Ca >1mg/dL above accepted range
24 hr urinary Ca > 400mg Creatinine Clearance dec by 30% Bone Density T score < -2.5 at any site Age < 50 |
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Rx for HyperPTH if surgery not indicated?
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Ambulation and Adequate Hydration
Avoid Thiazed Diuretics Avoid high or low Ca diets Bisphosphonates may protect bones Calcimimetics Twice yearly check up |
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Causes of Secondary HyperPTH?
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Vit D/Ca Def
End Stage Kidney Disease Hypercalciuria |
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How do you distinguish between Hypercalciuria Hypocalcemia and Vitamin D Def hypocalcemia?
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24 urinary calcium
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How much Ca per day to treat hypocalcemia?
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1000-2000mg
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how much Vit D to Rx def per day?
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400-4000 units
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What can you give someone w/ Vitamin D deficiency secondary to renal disease (i.e. can't convert 25 to 1,25)
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Recaltrol
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