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14 Cards in this Set

  • Front
  • Back

Calcitonin (Salmon)

Rx: Hypercalcemia, Paget's, Osteoporosis




MoA: ↑ Bone Deposition, ↓ Gut Absorption, ↓ Renal Reabsorption

PTH

Rx: Hypocalcemia




MoA: ↑ Bone Resorption, ↑ Gut Absorption, ↑ Renal Reabsorption, RANKL stimulation

Teriparatide

Rx: Hypocalcemia




MoA: ↑ Bone Resorption, ↑ Gut Absorption, ↑ Renal Reabsorption, RANKL stimulation

Cholecalciferol (D3)

Rx: Hypoparathyroid, Rickets




MoA: ↑ Ca+ / PO4 absorption

Ergocalciferol (D2)

Rx: Hypoparathyroid, Rickets




MoA: ↑ Ca+ / PO4 absorption

Etidronate

Rx: Hypercalcemia, Paget's, Osteoporosis




MoA: Slow formation / dissolution of Hydroxyapatite crystals, Blocks Farnesyl Pyrophosphate




S/E: ↓ Renal Function, Esophageal Motility Disorder, Peptic Ulcer, Osteonecrosis of Jaw

Pamidronate

Rx: Hypercalcemia, Paget's, Osteoporosis




MoA: Slow formation / dissolution of Hydroxyapatite crystals, Blocks Farnesyl Pyrophosphate




S/E: ↓ Renal Function, Esophageal Motility Disorder, Peptic Ulcer

Alendronate

Rx: Hypercalcemia, Paget's, Osteoporosis




MoA: Slow formation / dissolution of Hydroxyapatite crystals, Blocks Farnesyl Pyrophosphate




S/E: ↓ Renal Function, Esophageal Motility Disorder, Peptic Ulcer

Risendronate

Rx: Hypercalcemia, Paget's, Osteoporosis




MoA: Slow formation / dissolution of Hydroxyapatite crystals, Blocks Farnesyl Pyrophosphate




S/E: ↓ Renal Function, Esophageal Motility Disorder, Peptic Ulcer

Zolendronate

Rx: Hypercalcemia, Paget's, Osteoporosis




MoA: Slow formation / dissolution of Hydroxyapatite crystals, Blocks Farnesyl Pyrophosphate




S/E: ↓ Renal Function, Esophageal Motility Disorder, Peptic Ulcer, Osteonecrosis of Jaw

Denusomab

Rx: Osteoporosis, Giant Cell Bone Tumor




MoA: Inhibits RANKL

Cinacalcet

Rx: Hyperparathyroid (Secondary to CKD), Parathyroid Carcinoma




MoA: Stimulates Parathyroid Ca+ receptors, thus blocking PTH secretion

Plicamycin

Rx: Hypercalcemia, Paget's




MoA: Cytotoxic antibiotic inhibits bone resorption

Gallium Nitrate

Rx: Hypercalcemia