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117 Cards in this Set

  • Front
  • Back
Most common clinical presentation of pinworm?
perianal pruritis
Diagnosis of pinworm
Scotchtape test
Size/morphology of pinworm
females larger than males, pin at one end
Treatment for pinworm (enterobius)
Albendazole
Association of pinworm w/?
D. fragilis
Heavy Whipworm infection assoc with?
Rectal prolapse
Tx for trichuris (whipworm)
Albendazole
Ascaris mode of infection
ingestion of eggs
Ascaris infection can cause?
Loefflers, intestinal obstruction, biliary dz
Tx of ascaris
Albendazole
Clinical presentation of hookworm
iron deficiency anemia
What can you get by walking in sand
Strongyloides, Ancylostoma (old world hookworm), Necator (new world hookworm)
Where do you see hyperinfection syndrome?
Strongyloides in immuno compromised pts and steroids
Tx of strongyloides
Ivermectin
How to diagnose visceral larva migrans?
Serology (Elisa)
How do you get Anisakiasis
eating raw marine fish and squid
Tx of visceral larva migrans
Albendazole, DEC
Diagnosis of anisakiasis
Hx, symptoms of abd pain, Xray
Trichinella spiralis
get it from eating undercooked pork; encyst in muscle, heart, brain
Symptoms of trichinosis
myalgias, eosinophilia, periorbital edema, conjunctivitis, myocarditis
Diagnosis of trichinosis
serology, muscle biopsy
How do you get Drancunculus?
ingest copepods in water
Loa loa (african eye worm) transferred by what
Chrysops fly
Calabar swelling?
loa loa
Tx of loa loa (african eye worm)
DEC, corticosteroids before tx of meningoencephalitis
Diagnosis of loa loa (african eye worm)
blood smear during DAY, microfilariae
Onchocerca volvulus AKA?
River blindness BLACK
Eye manifestations leading to blindness, adult within dermal nodules, hanging groin
Transmission of onchocerca?
Blackfly
Tx of onchocerca (river blindness)
Ivermectin
Wucheria bancrofti (filariasis)
transmitted by mosquito
Tx of Wucheria bancrofti (filariasis)
DEC
Symptoms of Wucheria bancrofti (filariasis)
lymphangitis, elefantiasis, Tropical pulmonary eosinophilia, chyluria
lymphangitis, elefantiasis, Tropical pulmonary eosinophilia, chyluria
Symptoms of Wucheria bancrofti (filariasis)
Will drugs help when you get elefantiasis?
No, its a plumbing problem then. Wucheria bancrofti (filariasis) can be treated with DEC early on
What causes Tropical pulmonary eosinophilia?
seen in wucheria bancrofti; asthma like condition, high IgE
Diurnal variation vs nocturnal variation
Diurnal- loa loa

nocturnal- wucheria bancroft
Elevated IgM
African trypanosomiasis (african sleeping sickness)
Chagoma and periorbital edema (Romano's sign)
Trypanosoma cruzi, American trypanosome;Chagas' Dz
Transmissino of trypanosoma cruzi, American trypanosome;Chagas' Dz
kissing bug (reduviid bug)
Chronic chagas' dz
cardiomyopathy, megacolon, megaesophagus,
How to diagnose chronic chagas'
Serology
Tx of chagas
Nifurtimox, benznidazole
can cause TORCH like syndrome
Chagas
Pseudopolyps and colonic stenosis
S. mansoni
Clay pipe stem fibrosis
seen in S. mansoni
Ascending cholangitis
fasciola, clonorchis, opisthorcis
Dx of fasciola
Eggs in stool, serology
Tx of fasciola
Triclabendazole
Tx of severe malaria
IV quinidine plus doxy or artesunate
Tetrad for babesia
know it for test on histology
Babesia
transmitted by ticks
How to diagnose Microsporidia
unmodified trichrome
AIDs related diarrhea not picked up on other routine stains
Microsporidia
D. latum
ingest raw fish, also causes vit B12 deficiency causing megaloblastic anemia
Tx of d latum
Praziquantal
Pt comes in cyst with scolex in it

Tx
cysticercosis caused by taenia solium (not taeniasis)

Tx: albendazole with steroids (taeniasis tx: Praziquantal since definitive host)
how do you get cystic hydatid dz
dog tapeworm echinococcus, eating dog feces
where do cysts go in cystic hydatid dz (echinococcus)
anywhere
Tx of cystic hydatid dz (echinococcus)
albendazole tx for months, then surgery
3 major clinical syndromes of leishmaniasis
visceral, cutaneous, mucosal
What does L donovani of leishmaniasis cause?
causes hepatosplenic dz, pancytopenia, hepatosplenomegaly
Leishmaniasis can be confused witrh
shisto, malaria
Diag of leish
Need NNN media
Tx of leish
liposomal Ampho B
Mucosal Leish
L braziliensis, panamensis, guayanensis
Tx of Cutaneous Leish
give IV styvogluconate (pentostam?) (antimony?)
What do you give DEC for?
wucheria bancrofti (filariasis, elephantiasis, tropical pulmonary eosinophilia, chyluria)

Loa loa (african eye worm)
What gives you calabar swellings?
Loa loa (african eye worm)-
What protozoa cause a non-bloody diarrhea?
giardia and cyclospora
What protozoa cause a bloody diarrhea?
entamoeba histolytica
What causes liver abscesses?
Entamoeba histolytica, Ascaris, Fasciola
Where does Leishmania donovani live in the body?
Macrophages containing amastigotes
What organism makes flask-shaped ulcers? Where?
Entamoeba histolytica
Toxic megacolon
What do you find D. fragilis with?
Pinworm (enterobius)
What are the symptoms of amebiasis?
Organism isEntamoeba histolytica,

bloody and mucus diarrhea, toxic megacolon, perforation, appendicitis
How do you treat Balantidium coli? (its invasive)
tetracycline
Dx of toxocara (visceral larva migrans, ocular larva migrans)
serology
How do you treat things with larva? (such as toxocara, ancylostoma brazilienze)
Albendazole
Tx for cryptosporidia?
Nitazoxanide (children and HIV)
Winterbottom sign?
Trypanosome brucei (African sleeping sickness)
How do we get toxocara canis?
eggs shed in stool from dogs,
we ingest these eggs
What does toxocara canis cause?
Visceral larva migrans- eosinophilia, fever, hepatomegaly (ages 2-4) pica

Ocular larva migrans- eosinophilic inflammatory mass. children and adults
what are the causes of visceral larva migrans?
toxocara canis (from dog)

Baylisascaris (raccoons)
What can baylisascaris from raccoon cause?
Visceral larva migrans.

SEVERE meningoencephalitis
You notice a serpiginous track on the feet. What do you suspect?

How to treat?
Ancylostoma braziliense. (dog/cat hookworm)

Albendazole.
Pt comes in complaining of violent abdominal pain, nausea and vomiting shortly after eating. what do you suspect? What did he eat?
anisakiasis.

raw or undercooked fish
What causes tropical pulmonary eosinophilia?
Wucheria Bancrofti
Painless unilateral peri-orbital edema (Romano’s sign)
Trypanosoma cruzi Acute phase of Chagas disease
Intense itching; hanging groin, river blindness
Onchocerca volvulus
pt has eosinophilic meningoencephalitis, with hx of ingesting raw snails and prawns.
Angiostrongylus cantonensis
strawberry cervix. What is it?
How to diagnose?
How do you treat?
how do you get it?
Trichomonas vaginalis

Trophozoite on wet mount

Metronidazole

ONLY thru SEXUAL CONTACT
Acid-fast and self-limiting diarrhea in immune competent host?
Cryptosporidia
Cyclospora
Isospora
What does giardia cause?
EXPLOSIVE watery diarrhea

impaired absorption of fat and vit B12

offensive yellow stools, faltulence.
How to diagnose microsporidia?
UNMODIFIED TRICHROME
If left untreated, what can cause cholangiocarcinoma?
Clonorchis
Tx of giardia
Metronidazole
Tx of entamoeba histolytica?
Metronidazole AND

Iodoquinol (to treat asymptomatic cysts)
How do you treat strongyloides?
Ivermectin
Ingested raw fish and sick. How to differentiate?
Cholangitis/cholangiocarcinoma-clonorchis

Megaloblastic anemia (B12 deficiency)- D. Latum

nausea, vomiting, violent abd pain- anisakiasis
What is the cause of rectal prolapse?
Whipworm (trichuris trichiura)
How to treat rectal prolapse?
push it back in

since it is trichruris trichiura, give albendazole
Tx of cyclospora and isospora?
Bactrim
How do you treat babesia?
Clindamycin and quinine
What organism requires the duffy receptor on RBCs?
P. vivax
Tx for T. gondi?

Prophylaxis for T. gondi?
Tx: sulfadiazine+pyrimethamine

Prophy:Bactrim
Diagnosis of T. gondi
Serology-anti-T.gondi antibodies

salt and pepper scarring in retina
Symptoms of T. gondi in immune competent pts.

"..." in immunodeficient
1-2 week incubation
immunecompetent- most asymptomatic, lymphadenopathy w/o fever

immunedeficient-encephalitis, cough and fever, retinochoroiditis
Pt asymptomatic with B. hominis. What do you do?
nothing
What do you give steroids with?

What do you NOT give steroids with?
Loa loa w/meningoencephalitis- DEC and steroids

neurocysticercosis-albendazole and steroids. also check eyes

Strongyloides- dont give bc hyperinfection, and can spread everywhere!!!!
associated with eating imported foods like raspberries
cyclospora
how to diagnose and treat PCP?
Sputum:silver stain/giemsa

Tx:Bactrim as prophylaxis, corticosteroids if pt has severe pneumonia with O2 defects
how is trypanosome cruzi transmitted (vector)? what dz does it cause?
Kissing bug

Chagas Dz
Tx for Chagas?
Nifurtimox/Benznidazole is tx for Chagas (trypanome cruzi)
How do you diagnose Chagas?
Trypomastigotes in blood smear (acute stage)

Serology (chronic stage)
problems in chronic chagas?
pseudocysts in heart muscle, bundle branch block, cardiomyopathy, megaesophagus, megacolon
What dz can you acquire from transfusion, congenital, and transplantation?
Chagas
Vector of trypanosome brucei
tsetse fly. African sleeping sickness