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31 Cards in this Set
- Front
- Back
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trematodes have a simple ___, and most are ___
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digestive tract
hermaphrodites |
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important trematode genera (4)
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schistosoma
fasciola clonorchis paragonimus |
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major human schistosome parasites (3)
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s. mansoni
s. japonicum s. hematobium |
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s. mansoni is endemic to ___ (3) and has ___ as IH
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africa
middle east south america biomphalaria |
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s. japonicum is endemic to ___ (2) and has ___ as IH
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china
southeast asia oncomelania |
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s. hematobium is endemic to ___ (2) and has ___ as IH
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africa
arabia bulinus |
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schistosomes are unusual trematodes in that ___
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reproduce sexually
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schistosomes home to ___ (2)
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portal vein
bladder vasculature |
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1st larval stage of schistosome is ___ and infects ___. 2nd stage is ___ and infects ___
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miracidium
snail cercaria human |
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although worms do not ___ inside host, eggs do. ___ eggs have a spine
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trigger immune response
s. mansoni |
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schistosomiasis symptoms are caused by ___
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eggs
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cutaneous symptoms of schistosomiasis
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dermatitis
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GI symptoms of schistosomiasis (4)
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pain
ascites diarrhea bloody stool |
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urogenital symptoms of schistosomiasis (3)
cause of symptoms |
chronic cystitis
urethritis hematuria granulomatous fibrosis |
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drug for schistosomiasis
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praziquantel
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schistosome cercaria evades immune response by ___
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shedding glycocalyx after penetrating skin
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schistosomes do passive molecular mimicry by ___
they do active molecular mimicry by ___ |
taking MHC and blood group antigens from RBCs and using them
expressing their own versions of host proteins |
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Fasciolopsis buski is a ___
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hermaphrodite
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F. buski life cycle is identical to ___ with the addition of ___ before ___.
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schistosome
differentiation to metacercaria on a second IH infecting humans |
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metacercaria are
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cysts
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f. buski is associated with eating ___
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chestnuts
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drug for f. buski
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praziquantel
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clonorchis sinensis life cycle is identical to that of ___, except ___
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f. buski
2nd IH is fish |
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c. sinensis homes to ___ and is aka ___
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liver
human liver fluke |
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c. sinensis symptoms (4)
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liver dysfunction
hepatomegaly liver necrosis indigestion |
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c. sinensis drug
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praziquantel
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paragonimus westermani is endemic to ___
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china
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p. westermani life cycle is identical to ___ except ___ (2)
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f. buski
2nd IH is crab eggs are released into lungs and are spread via sputum |
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p. westermani symptoms (3)
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dry cough
pleurisy rusty-brown sputum |
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if p. westermani can go to ___ and cause ___
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brain
epilepsy |
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p. westermani drugs (2)
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bithionol
praziquantel |
