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8 Cards in this Set
- Front
- Back
Amoeba
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Acanthopodia - Spike-like pseudopods
Lobopodia - Large, blunt pseudopodia |
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Definitions: Sexual Phases
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Schizogony -Asexual repro by multiple fission
- Apicomplexans Sporogony - Asexual repro within oocyst - Apicomplexans Cyst - non-motile, transmission state Trophozoite - Active, motile, growing stage |
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Entamoeba histolytica
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Amoebic dysentery: non-host specific
Luminal - No signs Invasive Intestinal - ameoba attach to epith cells, lyse them and intracell. junctions - Secretory d+, colitis, dysentery - flask-shaped ulcers Invasive extraintestinal - rare, invades liver, peritoneum, etc Life Cycle: Direct. Accidental ingestion of cyst by host in food/water contam by feces - Mature cyst: 4 nuclei, in lower gut - Releases 4 trophozoites - Binary fission, form cysts, pass in feces Usually humans -> pets Morphology - Trophozoite: Carwheel nucleus w/ endosome, "spokes", blunt pseudopods Cyst - Chromatoid bodies in cytoplasm - cigar shaped, rounded, 4 nuclei Tx - Metronidazole |
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Entamoeba invadens
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Reptilian, similar to E. histolytica, severe for captive snakes/tortoises
D+, anorexia, listlessness Multifocal hepatic necrosis Trophozoite more active at room temp |
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Acanthamoeba
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Free-living: water, soil, sewage
Accident parasite - resp/ skin break - Hematogenous spread possible - Immunocompromised people Humans - chronic keratitis (contacts) Granulomatous amoebic encephalitis Dog - epizootic in greyhounds - 35% mortality - chronic ganulomatous infect, pneumonia/meningitis (neuro signs), oculonasal discharge Trophozoite (asexual repro)/cyst - Pointed pseudopodia, look like macro, "bulls-eye Tx - None |
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Naegleria fowleri
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Free living - mainly humans (accidental)
- Primary Amoebic Meningoencephalitis (hemorrhagic necrotizing, all fatal), thermally enriched H2O Trophozoite/cyst enter nasal cavity - CNS via olfactory nerve, can infect lungs Dx - ID in CSF/brain biopsy Tx - Amphotericin B |
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Ciliophora - Balantidium suis
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Swine commensal, zoonotic human pathogen (B. coli)
- Increase in swine dysentery Direct cycle, fecal-oral thick-walled cyst trans. Trophozoite in colon lumen - No signs/lesions - Large macromolecules, tiny nucleus |
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Ichthyophthirius multifiliis
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Ich (White Spot Disease) - Fish
- Small white dots on skin/gills - Large ciliate leaves host - forms repro cyst, prod + tomites (free-swimming, 48 hrs to find host, tx works) |