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42 Cards in this Set

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Cardizem(diltiazem hydrochloride)

CLASS
Calcium channel blocker
Cardizem(diltiazem hydrochloride)

MECHANISM OF ACTION
block influx of calcium ions into cardiac muscle; prevents spasm of coronart arteries. Arterial and Venus vasodilator. Reduces preload and afterload. Reduces myocardial oxygen demand.
Cardizem(diltiazem hydrochloride)

INDICATION
control rapid ventricular rates due to atrial flutter , afib, and re-entry SVT, angina pectoris
Cardizem(diltiazem hydrochloride)

CONTRAINDICATIONS
HYN, sick sinus, 2nd or 3rd degree AV block, cardiogenic shock, wide complex tach, poison / drug induced tach
Cardizem(diltiazem hydrochloride)

ADVERSE REACTIONS
bradycardia, 2/3rd degree block, chest pain, chy, syncope, v-fib, v-tach, nausea, vommiting, dizziness, dry mouth, dyspnea, headache
Cardizem(diltiazem hydrochloride)

CLASS
Calcium channel blocker
Cardizem(diltiazem hydrochloride)

MECHANISM OF ACTION
block influx of calcium ions into cardiac muscle; prevents spasm of coronart arteries. Arterial and Venus vasodilator. Reduces preload and afterload. Reduces myocardial oxygen demand.
Cardizem(diltiazem hydrochloride)

INDICATION
control rapid ventricular rates due to atrial flutter , afib, and re-entry SVT, angina pectoris
Cardizem(diltiazem hydrochloride)

CONTRAINDICATIONS
HYN, sick sinus, 2nd or 3rd degree AV block, cardiogenic shock, wide complex tach, poison / drug induced tach
Cardizem(diltiazem hydrochloride)

ADVERSE REACTIONS
bradycardia, 2/3rd degree block, chest pain, chy, syncope, v-fib, v-tach, nausea, vommiting, dizziness, dry mouth, dyspnea, headache
Cardizem(diltiazem hydrochlorid

DRUG INTERACTIONS
caution in patiens using medications that affect cardiac contractility. In general, should not be used on patients using beta blockers
Cardizem(diltiazem hydrochloride)

DOSAGE AND ADMINISTRATION
ADULT: .25mg/kg IV over 2min
RPT 15min if inadaquate response then: .35mg/kg over 2min

15mg -20mg avg doses
Cardizem(diltiazem hydrochloride)

DURATION OF ACTION
ONSET: 2-5min
PEAK: variable
DURATION: 1-3 hours
Dopamine (intropin)

CLASS
Sympathomimetic, inotropic agent
Dopamine (intropin)

MECHANISM OF ACTION
immediate metabolic precursor to norepinephrine. Increases systemic vascular resistance, dilates renal and splanchnic vasulature. Increases myocardial contractility and stroke volume.
Dopamine (intropin)

INDICATIONS
cardiogenic, septic or spinal shock, hypotension with low cardiac output states, distributive shock
Dopamine (intropin)

CONTRAINDICATIONS
hypovolemic shock, pheochromocytoma, tachyarrhythmias, v-fib
Dopamine (intropin)

ADVERSE REACTIONS
cardiac arrhythmias, htn, increased mycardial oxygen demand, extravastion may cause tissue necrosis
Dopamine (intropin)

DRUG INTERACTIONS
Incompatable in alkaline solutions. MAOIs will enhanse effects of dopamine. Bretylium may potentate effect of dapamine. Betablockers may antagonize effect of dopamine. When administered with phenytoin: may cause hypotension, bradycardia and seziures
Dopamine (intropin)

DOSAGE AND ADMINISTRATION
ADULT: 2-20 micrograms /kg/min
2-4 micrograms/kg/min- renal dosing
5-10 micrograms/kg/min- cardiogenic effect
10-20- micrograms/kg/min - vasoconstriction - bring up bp
Dopamine (intropin)

DURATION OF ACTION
ONSET: 1-4min
PEAK: 5-10min
DURATION: cease almost immediatly when shut off
dobutamine (dobutrex)

CLASS
sympathomimetic, intropic agent
dobutamine (dobutrex)

MECHANISM OF ACTION
synthetic cathecholamine. increased myocardial contractility and stroke volume, inccreased cardiac output. minimal chronotropic activity. inccreases renal blood flow.
dobutamine (dobutrex)

INDICATIONS
cardiogenic shock, chf, left ventricular dysfunction. often used conjunction with other drugs
dobutamine (dobutrex)

CONTRAINDICATIONS
tachyarrhythmias, IHSS, severe hypotension
dobutamine (dobutrex)

ADVERSE REACTIONS
may increase infarct size in patient with MI , headache, arrhythmias, HTN, PVCs
dobutamine (dobutrex)

DRUG INTERACTIONS
incompatable with sodium bicarbonate and furosemide. betablockers may blunt inotropic effects
dobutamine (dobutrex)

DOSAGE AND ADMINISTRATION
ADULT: 2-20 McG/kg/min titrated to effect

2-4 micrograms/kg/min- renal dosing
5-10 micrograms/kg/min- cardiogenic effect
10-20- micrograms/kg/min - vasoconstriction - bring up bp
dobutamine (dobutrex)

DURATION OF ACTION
ONSET: 2min
PEAK: 10min
DURATION: ends 1-2 min after being discontinued
naloxone Hydrochloride (narcan)

CLASS
narcotic antagonist
naloxone Hydrochloride (narcan)

MECHANISM OF ACTION
competitive inhibition at narcotic receptor sites reverse respiratory depression secondary to depressant drugs completely inhibits the effects of morphine
naloxone Hydrochloride (narcan)

INDICATIONS
opiate OD, coma, complete or partial reversal of CNS and respiratory depression induced by opioids decresed level of consciousness; coma, of unknown origin, carcotic antagist for the following: morphine, heroin, hydromorphine, methadone, meperidine, paregoric, fentanyl, oxycodone, codine, propoxyphene, narcotic angonist and antagonist for the following: butophanol, pentazocine, nalbuphine
naloxone Hydrochloride (narcan)

CONTRAINDICATIONS
use with caution in narcotic-dependent patients, use with caution in neonates of narcotic-addicted mothers
naloxone Hydrochloride (narcan)

ADVERSE REACTIONS
hypotension,bradycardia, facial flushing, respiratory deprerssion, CNS depression, euphoria, paradoxical CNs simulation, blurred vision
naloxone Hydrochloride (narcan)

DRUG INTERACTIONS
CNS depressants may potentiates effects
naloxone Hydrochloride (narcan)

DOSAGE AND ADMINISTRATION
0.4 - 2.0 mg IV , IM, SC, or ET
min dose 2.0 mg, rpt 5min max 10mg
naloxone Hydrochloride (narcan)

DURATION OF ACTION
ONSET:2min
PEAK:variable
DURATION:30-60min
Fentanyl

Class
Opoid analegic
Fentanyl

Dose
25 - 100mcg IV
Fentanyl

indication
pain relief, anesthesis
Fentanyl

containdications
apnes, laryngospasm, bronchospasm, cold clammy skin, cyanosis, coma
Fentanyl

action / thereputic effect
binds at opiate receptor sites in cns reucing stimuli from sensory nerve endings, addecting pain perception emotional response to pain