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42 Cards in this Set
- Front
- Back
Cardizem(diltiazem hydrochloride)
CLASS |
Calcium channel blocker
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Cardizem(diltiazem hydrochloride)
MECHANISM OF ACTION |
block influx of calcium ions into cardiac muscle; prevents spasm of coronart arteries. Arterial and Venus vasodilator. Reduces preload and afterload. Reduces myocardial oxygen demand.
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Cardizem(diltiazem hydrochloride)
INDICATION |
control rapid ventricular rates due to atrial flutter , afib, and re-entry SVT, angina pectoris
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Cardizem(diltiazem hydrochloride)
CONTRAINDICATIONS |
HYN, sick sinus, 2nd or 3rd degree AV block, cardiogenic shock, wide complex tach, poison / drug induced tach
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Cardizem(diltiazem hydrochloride)
ADVERSE REACTIONS |
bradycardia, 2/3rd degree block, chest pain, chy, syncope, v-fib, v-tach, nausea, vommiting, dizziness, dry mouth, dyspnea, headache
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Cardizem(diltiazem hydrochloride)
CLASS |
Calcium channel blocker
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Cardizem(diltiazem hydrochloride)
MECHANISM OF ACTION |
block influx of calcium ions into cardiac muscle; prevents spasm of coronart arteries. Arterial and Venus vasodilator. Reduces preload and afterload. Reduces myocardial oxygen demand.
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Cardizem(diltiazem hydrochloride)
INDICATION |
control rapid ventricular rates due to atrial flutter , afib, and re-entry SVT, angina pectoris
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Cardizem(diltiazem hydrochloride)
CONTRAINDICATIONS |
HYN, sick sinus, 2nd or 3rd degree AV block, cardiogenic shock, wide complex tach, poison / drug induced tach
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Cardizem(diltiazem hydrochloride)
ADVERSE REACTIONS |
bradycardia, 2/3rd degree block, chest pain, chy, syncope, v-fib, v-tach, nausea, vommiting, dizziness, dry mouth, dyspnea, headache
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Cardizem(diltiazem hydrochlorid
DRUG INTERACTIONS |
caution in patiens using medications that affect cardiac contractility. In general, should not be used on patients using beta blockers
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Cardizem(diltiazem hydrochloride)
DOSAGE AND ADMINISTRATION |
ADULT: .25mg/kg IV over 2min
RPT 15min if inadaquate response then: .35mg/kg over 2min 15mg -20mg avg doses |
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Cardizem(diltiazem hydrochloride)
DURATION OF ACTION |
ONSET: 2-5min
PEAK: variable DURATION: 1-3 hours |
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Dopamine (intropin)
CLASS |
Sympathomimetic, inotropic agent
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Dopamine (intropin)
MECHANISM OF ACTION |
immediate metabolic precursor to norepinephrine. Increases systemic vascular resistance, dilates renal and splanchnic vasulature. Increases myocardial contractility and stroke volume.
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Dopamine (intropin)
INDICATIONS |
cardiogenic, septic or spinal shock, hypotension with low cardiac output states, distributive shock
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Dopamine (intropin)
CONTRAINDICATIONS |
hypovolemic shock, pheochromocytoma, tachyarrhythmias, v-fib
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Dopamine (intropin)
ADVERSE REACTIONS |
cardiac arrhythmias, htn, increased mycardial oxygen demand, extravastion may cause tissue necrosis
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Dopamine (intropin)
DRUG INTERACTIONS |
Incompatable in alkaline solutions. MAOIs will enhanse effects of dopamine. Bretylium may potentate effect of dapamine. Betablockers may antagonize effect of dopamine. When administered with phenytoin: may cause hypotension, bradycardia and seziures
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Dopamine (intropin)
DOSAGE AND ADMINISTRATION |
ADULT: 2-20 micrograms /kg/min
2-4 micrograms/kg/min- renal dosing 5-10 micrograms/kg/min- cardiogenic effect 10-20- micrograms/kg/min - vasoconstriction - bring up bp |
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Dopamine (intropin)
DURATION OF ACTION |
ONSET: 1-4min
PEAK: 5-10min DURATION: cease almost immediatly when shut off |
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dobutamine (dobutrex)
CLASS |
sympathomimetic, intropic agent
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dobutamine (dobutrex)
MECHANISM OF ACTION |
synthetic cathecholamine. increased myocardial contractility and stroke volume, inccreased cardiac output. minimal chronotropic activity. inccreases renal blood flow.
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dobutamine (dobutrex)
INDICATIONS |
cardiogenic shock, chf, left ventricular dysfunction. often used conjunction with other drugs
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dobutamine (dobutrex)
CONTRAINDICATIONS |
tachyarrhythmias, IHSS, severe hypotension
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dobutamine (dobutrex)
ADVERSE REACTIONS |
may increase infarct size in patient with MI , headache, arrhythmias, HTN, PVCs
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dobutamine (dobutrex)
DRUG INTERACTIONS |
incompatable with sodium bicarbonate and furosemide. betablockers may blunt inotropic effects
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dobutamine (dobutrex)
DOSAGE AND ADMINISTRATION |
ADULT: 2-20 McG/kg/min titrated to effect
2-4 micrograms/kg/min- renal dosing 5-10 micrograms/kg/min- cardiogenic effect 10-20- micrograms/kg/min - vasoconstriction - bring up bp |
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dobutamine (dobutrex)
DURATION OF ACTION |
ONSET: 2min
PEAK: 10min DURATION: ends 1-2 min after being discontinued |
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naloxone Hydrochloride (narcan)
CLASS |
narcotic antagonist
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naloxone Hydrochloride (narcan)
MECHANISM OF ACTION |
competitive inhibition at narcotic receptor sites reverse respiratory depression secondary to depressant drugs completely inhibits the effects of morphine
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naloxone Hydrochloride (narcan)
INDICATIONS |
opiate OD, coma, complete or partial reversal of CNS and respiratory depression induced by opioids decresed level of consciousness; coma, of unknown origin, carcotic antagist for the following: morphine, heroin, hydromorphine, methadone, meperidine, paregoric, fentanyl, oxycodone, codine, propoxyphene, narcotic angonist and antagonist for the following: butophanol, pentazocine, nalbuphine
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naloxone Hydrochloride (narcan)
CONTRAINDICATIONS |
use with caution in narcotic-dependent patients, use with caution in neonates of narcotic-addicted mothers
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naloxone Hydrochloride (narcan)
ADVERSE REACTIONS |
hypotension,bradycardia, facial flushing, respiratory deprerssion, CNS depression, euphoria, paradoxical CNs simulation, blurred vision
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naloxone Hydrochloride (narcan)
DRUG INTERACTIONS |
CNS depressants may potentiates effects
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naloxone Hydrochloride (narcan)
DOSAGE AND ADMINISTRATION |
0.4 - 2.0 mg IV , IM, SC, or ET
min dose 2.0 mg, rpt 5min max 10mg |
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naloxone Hydrochloride (narcan)
DURATION OF ACTION |
ONSET:2min
PEAK:variable DURATION:30-60min |
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Fentanyl
Class |
Opoid analegic
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Fentanyl
Dose |
25 - 100mcg IV
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Fentanyl
indication |
pain relief, anesthesis
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Fentanyl
containdications |
apnes, laryngospasm, bronchospasm, cold clammy skin, cyanosis, coma
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Fentanyl
action / thereputic effect |
binds at opiate receptor sites in cns reucing stimuli from sensory nerve endings, addecting pain perception emotional response to pain
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