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30 Cards in this Set
- Front
- Back
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What is a Drug?
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Chemical used to diagnose, treat, or prevent disease.
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What is Pharmacology?
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The study of drugs and their interactions with the body.
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What is Assay?
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Test that determines the amount and purity of a given chemical in a preparation in the laboratory.
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What is Bioquivalence?
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Relative therapeutic effectiveness of chemically equivalent drugs.
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What is Bioassay?
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Test to ascertain a drug's availability in a biological model.
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What are the 6 Rights of Medication Administration?
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Right Medication
Right Dose Right Time Right Route Right Patient Right Documentation |
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What is Dose Packaging?
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medication packages caintain a single dose for a single patient.
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What are Teratogenic Drugs?
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Medication that may deform or kill the fetus.
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What is the Free Drug Availability?
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Proportion of a adrug available in the body to cause either desired or undesired effects.
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What is Pharmacokinetics?
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How a drug is absorbed, distributed, metabolized (biotransformed), and excreted; how drugs are transported into and out of the body.
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What is Carrier-Mediated Diffusion or Facilitated Diffusion?
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Process in which carrier protiens transport large molecules across the cell membrane.
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What is Passive Transport?
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Movement of a substance without the use of energy.
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What is Filtration?
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Movement of molecules across a membrane from an area of higher pressure to an area of lower pressure.
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What does it mean to Ionize?
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To become electrically charged or polar.
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What is Bioavailability?
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Amount of a drug that is still active after it reaches its target tissue.
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What is the Blood-Brain Barrier?
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Tight junctions of the capillary endothelial cells in the central nervous system vasculature through which only non-protien-bound, highly-soluble drugs can pass.
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What is the Placental Barrier?
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Biochemical barrier at the maternal/ fetal interface that restricts certain molecules.
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What is Biotransformation?
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Special name given to the metabolism of drugs.
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What are Prodrugs (Parent Drugs)
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Medicationthat is not active when administered, but whose biotransformation converts it into active metabolites.
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What is the First-Pass Effect?
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The liver's partial or complete inactivation of a drug before it reaches the systemic circulation.
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What is Oxidation?
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The loss of hydrogen atoms or the acceptance of an oxygen atom. This increases the positive charge (or lessens the negative charge) on the molecule.
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What is Hydrolysis?
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The breakage of a chemical bond by adding water, or by incorporating a hydroxyl (OH-) group into one fragment and a hydrogen ion (H+) into the other.
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What is Enteral Route?
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Delivery of a medication through the gastrointestinal tract.
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What is the Parenteral Route?
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Delivery of a medication outside of the gastrointestinal tract, typically using needles to inject medications into the circulatory system or tissues.
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Where are most Emergeny Medications delivered and why?
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Most emergency medications are given intravenously to avoid drug degradation in the liver.
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What is a Receptor?
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Specialized protien that combines with a drug resulting in a biochemical effect.
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What is Affinity?
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Force of attraction between a drug and a receptor.
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What is Efficacy?
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A drug's ability to cause the expected response.
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What is a Second Messenger?
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Chemical that partipates in complex cascading reactions that eventually cause a drug's desired effect.
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What is Down-Regulation?
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Binding of a drug or hormone to a target cell receptor that causes the number of receptors to decrease.
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