Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
Description |
Non-steroidal analgesic and antipyretic |
|
Class |
non-opiod analgesia |
|
Indications |
Mild to moderate pain and fever |
|
Contraindications |
Hypersensitivity, previous doses within 4 hours or more than 4 grams ingested in <24 hours |
|
Pharmacokinetics |
Onset: 10-60 minutes - Peak: variable - Duration: 4 hours |
|
Adverse effects |
Nausea and GI irritation |
|
Precaution |
Dehydration and patients with suspected liver or renal disease May be combined with codeine or other opiates in certain medications |
|
Mechanism of action |
Inhibits cyclooxygenase (COX) enzymes resulting in subsequent reduction of prostaglandin signalling in the CNS to produce analgesic, antipyretic and anti-inflammatory effects |