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352 Cards in this Set

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Esophaggeal Bleeding (3)
Mallory-Weiss Tear
Esophageal Varices
Boerhaave's Syndrome
Mucosal tear of GE junction from vomiting
Mallory-Weiss Tear
Are Mallory-Weiss Tears painful?
Painless bleeding
Mallory-Weiss Tear Dx
EGD
Mallory-Weiss Tear Tx
Supportive
Dilated sub-mucosal veins in lower esophagus
Esophageal Varices
2 diseases common with Esophageal Varices
Portal HTN
Cirrhotic liver disease
Brisk, painless bleeding
Life-threatening emergency
Esophageal varices
Esophageal Varices Dx
EGD
Esophageal Varices Immediate Tx
EGD is Dx and Tx
Variceal Banding
Sclerotherapy
Esophageal Varices Long-Term Tx
Beta Blocker
No ETOH
Esophageal rupture/perforation
Boerhaaves's Syndrome
2 causes of Boerhaave's Syndrome
Instrumentation (EGD)
Severe retching/overeating
Hematemsis with severe retrosternal "tearing" pain
Boerhaave's Syndrome
Boerhaave's Syndrome Tx
CXR shows mediastinal widening
Esophogram rupture of lower esophagus
Boerhaave's Syndrome Dx
Not self-ltd
Emergent surgical consult
Painful swallow
Odynophagia
Difficult swallow
Dysphagia
Infectious Esophagitis cause
Candida esophagitis
Infectious Esophagitis Tx
Anti-fungal
New Onset upper GI complaint
Pill-Induced Esophagitis
Pill-Induced Esophagitis causes (4)
NSAIDs
KCl
Alendronate/Bisphosphonates
Doxy/Tetra
Dysphagia Dx
EGD
Dx to assess peristalsis/lower esophageal sphincter
Swallow or Esophageal Manometry
Oropharyngeal
CNS
Motility disorder of solids and liquids
Achalasia
Innervation abnormality dysphagia (4)
Achalasia
Esophageal spasm
Scleroderma
CVA
Structural abnormality dysphagia (4)
Schatzki's rings
Zenker's diverticulum
Esophageal web/stricture
Esophageal cancer
Poor peristalysis with ineffective swallow induced relaxation of the lower esophageal sphincter
Achalasia
EGD image
"Bird's Beak"
Achalasia Dx
Esophageal monometry shows poor peristalsis
Achalasia Tx
Botox injections at LES
Incoordinated motility
Nonpropulsive hyperperistalysis
"Food gets stuck"
LES normal
Diffuse Esophageal Spasm
Hyperperistalysis
LES HTN
Nutcracker esophagus
Diffuse Esophageal Spasm Tx
Self-LTD
Smooth, circumferential structures in the distal esophagus
Schatzki Ring
May develop from uncontrolled GERD, trauma (nasogastric tube), or infectious esophagitis
Esophageal Stricture
Schatzki Ring Tx
EGD
GERD/Infection Tx
Schatzki Ring Dx
EGD shows smooth lumen narrowing
Esophageal Stricture Tx
EGD
GERD/Infection Tx
Esophageal Stricture Dx
EGD shows smooth lumen narrowing
Regurgitation of undigested food, especially in am by older pt
Zenker's Diverticulum
Zenker's Diverticulum Dx
Barium esophagram (Do not want to risk blindly perforating during EGD
Zenker's Diverticulum Tx
Surgical in severe cases
May develop from result of Iron Difficiency anemia
Causes connective tissue effect
Esophageal Web
Plummer Vinson Syndrome
Iron Difficency Anemia caused esophageal web
Esophageal Web Tx
Tx anemia
EGD
Plummer Vinson Syndrome Tx
Tx anemia
EGD
2 types of Esophageal Cancer
Squamous
Adenocarcinoma
Squamous cell Esophageal Cancer ptss
Smokers, ETOF in SE Asians/African Americans
Adenocarcinoma Esophageal Cancer Pts
Barrett's Esophagus (White males)
Esophageal Cancer Dx
EGD for biopsy
Esophageal Cancer Tx
Surgical/Onc
Why use Barium Swallow?
Machanical v. motility disorders
Dilation and beaking (achalasia)
Rings, strictures, Zenker's Diverticulum
Why use Manometry
Assesses peristalsis in Achalasia
Uncomplicated GERD Tx
4 weeks on PPI
Test/treat for H. pylori
Reasons to send GERD pt for EGD (5)?
Pts who fail Tx
GI bleeding/anemia
Dysphagia/odynophagia
Wt loss
H/O Heavy NSAIDS, Ulcer disease
GERD Tx
Antacids
H2 Receptor Antagonists (-tidine)
PPIs QD before meals (-azoles)
Unresolved GERD Dx
EGD to rule out Barrett's
pH monitoring study (surgery if abnormal)
Surgical fundoplication
Squamous cells replaced wtih abnormal glandular-type epithelium on esophagus
Suspect in white male with GERD
Barrett's Esophagus
Barrett's Esophagus Issue
Adenocarcinoma of Esophagus
Barrett's Esophagus Dx
Biopsy
Orange-salmon colored change on mucosa
Barrett's Esophagus
Barrett's Esophagus Monitoring
1 yr follow up EGD followed by surveillance every 3-5 ears
If dysphagia at time of Dx, monitor with yearly EGD
Barrett's Esophagus Tx
Longer-term PPI therapy/ablation
Stomach Disorders (4)
PUD
NSAID Gastropathy
Zollinger Ellison Syndrome
Gastric carcinoma
More serious, but less common ulcer
Appears in older patients
Gastric Ulcer
Most common in NSAID overuse/H. pylori
PUD
Assumption if pt has PUD and they are not on NSAIDs/ASA
H. pylori
H. Pylori Dx Methods (4)
Serology-ELISA
Urea Breath Test
Stool Antigen
Endoscopic Biopsy
Serology-ELISA = still positive after Tx
Urea Breath Test = more expensive
Stool antigen = Tells if active infection, cost effective
Endoscopic Biopsy = Culture can be done to deetermine if active
H. pylori Tx
Amoxicillin 1 gm BID AND
Clarithromycin 500 mg BID AND
PPI BID

All for 10-14 days
Test stool antigen to confirm eradication
NSAID Gastropathy Tx
D/C NSAIDs, give with food, add PPI
Ulcer presenting with pain being worse after eating
Gastric Ulcer
Ulcer presenting with pain relieved by eating
Duodenal Ulcer
Ulcer Red Flags = Get EGD (7)
Anemia
Weight loss
Positive hemoccult stools
Hematemesis/melena
Persistent vomiting
Dysphagia
New-progressive symptoms
When to EGD Ulcer pts (3)
H/O PUD
Pts with red flags
Pts >50 with new onset symptoms
Empiric Tx v EGD for Ulcers
<50 yo
No red flags

PPI w reassessment in 4 weeks
Treat H. pylori if active
Stomach Issues Gold Standard Dx
EGD
Gastric Ulcer Tx
PPI BID x1 month
Then PPI QD x1 month
EGD to confirm eradication
Duodenal Ulcer Tx
PPI BID x1 month
Then PPI QD x1 month
Do not have to rescope with EGD
PUD + Peritoneal Signs/Ileus
Perforation
PUD + Gastric Outlet Obstruction
Vomiting after meals
PUD + Bleeding
Positive hemoccult/melena
Anemia
Gastrinoma of pancreas or duodenum
Zollinger-Ellison Syndrome
Recurrent PUD
PUD with hypercalcemia
Neg H. pylori, NSAID/ASA use
Severe abdominal pain/diarrhea
Serum gastrin level >150
Zollinger-Ellison Syndrome
Most common cancer worldwide, but uncommon in US
Gastric Carcinoma
Ulcer pt that loses weight
Gastric
Ulcer pt that gains weight
Duodenal
Indirect Bilirubin--Water Soluable?
No, urine color normal
Direct Bilirubin--Water Soluable?
Yes, dark colored urine
3 main causes of Indirect Bilirubinemia
Hemolysis
Gilbert's
Crigler-Najjar
Pre-liver issue
Indirect Bilirubinemia
Post-liver issue
Direct Bilirubinemia
Indirect bili is high
Indirect Bilirubinemia
Total and direct bili is high
Indirect is normal
Direct Bilirubinemia
3 causes of Direct Bilirubinemia
Hepatocellular dysfunction
Biliary obstructioni
Dubin-Johnson syndrome
Gallstones
Cholelithiasis
Gallstones in cystic duct
Cholecystitis
Stone in common bile duct
LFTs elevated
Choledocholithiasis
Bacteria in biliary tree
Cholangitis
Male autoimmune disease with Ulcerative Cholitis
Primary Sclerosing Cholangitis
Cholesterol stones
Cholelithiasis
5 F's of Cholelithiasis
Female
Fat
Forty
Fertile
Fair
Transient cystic duct obstruction
Nocturnal pain is common
Biliary Colic
Sustained obstruction of the cystic duct
Acute Cholecystitis
Murphy's Sign
Acute Cholecystitis
Biliary colic
Jaundice because stone has moved out of gallbladder
Elevated LFTs
Choledocholithiasis
Gallstone pancreatitis
Choledocholithiasis
Adenocarcinoma Esophageal Cancer Pts
Barrett's Esophagus (White males)
Esophageal Cancer Dx
EGD for biopsy
Esophageal Cancer Tx
Surgical/Onc
Why use Barium Swallow?
Machanical v. motility disorders
Dilation and beaking (achalasia)
Rings, strictures, Zenker's Diverticulum
Why use Manometry
Assesses peristalsis in Achalasia
Uncomplicated GERD Tx
4 weeks on PPI
Test/treat for H. pylori
Reasons to send GERD pt for EGD (5)?
Pts who fail Tx
GI bleeding/anemia
Dysphagia/odynophagia
Wt loss
H/O Heavy NSAIDS, Ulcer disease
GERD Tx
Antacids
H2 Receptor Antagonists (-tidine)
PPIs QD before meals (-azoles)
Unresolved GERD Dx
EGD to rule out Barrett's
pH monitoring study (surgery if abnormal)
Surgical fundoplication
Squamous cells replaced wtih abnormal glandular-type epithelium on esophagus
Suspect in white male with GERD
Barrett's Esophagus
Gallstone Pancreatitis
Choledocholithiasis
Charcot's Triad symptoms
Fever >40
RUQ pain
Jaundice
Reynold's Pentad symptoms
Fever >40
RUQ pain
Jaundice
Altered Mental Status
Hypotension
Charcot's Triad
Cholangitis
Reynold's Pentad
Cholangitis
First line Dx for liver/gallbladder
US
Dx used when pt has continual gallbladder pain but normal US
HIDA
Pain = Functional biliary Disease
ERCP uses
Dx and Tx:
Cholangitis
Choledocolithiasis
ERCP Risk
Pancreatitis
Elevated AlkPhos (4)
Congestion of liver
Cirrhosis
Obstruction
Sitting Bili
Increased ALT/AST (2)
Hepatitis
Hepatocites destroyed
Autoimmune, older women
Fatigue, jaundice, puritis, mild hepatomegally
Elevated AlkPhos
Primary Biliary Cirrhosis
Primary Biliary Cirrhosis Dx
+AMA
Used to stage inflammation/fibrosis in Primary Biliary Cirrhosis
Liver Bx
Primary Biliary Cirrhosis Tx
Bile acid sequestrant (URSOdiol)
Cure = transplant
Younger women with no serological evidence of viral hep or history of ETOH, parenteral exposure
Fatigue, anorexia, arthralgias, jaundice
Autoimmune Hepatitis
Elevated transaminases
+ANA
+ASMA
Autoimmune Hepatitis
Used to stage inflammation/fibrosis in Autoimmune Hep
Liver Bx
Tx of Autoimmune Hep
Prednisone
Immunomodulators (Azothioprine)
Autoimmune, post-infectious, vascular liver disease
Young men
Associated with IBD/UC
Primary Sclerosing Cholangitis
Chronic inflammation and fibrosis of the bile duct system
Primary Sclerosing Cholangitis
Elevated TB, Alk Phos
ERCP shows thick/narrowed bile duct system
Primary Sclosing Cholangitis
Klatskin tumor
Cholangiocarcinoma
Most common location for Cholangiocarcinoma
Junction of R and L main hepatic ducts
Nontender palpable gallbladder w H/O of weight loss
Cholangiocarcinoma
Caused by gallstones, chronic ETOH abuse, Type IV hypertriglyceridemia, ERCP, meds
Acute Pancreatitis
Meds that cause Acute Pancreatitis (4)
Azothioprine
Pentamide
Valproate
Thyazides
Pancreas Imaging
CT
Increased S. amylaase and S. lipase
Leukocytosis with a left shift
Acute Pancreatitis
Acute Pancreatitis Imaging
CT
Acute Pancreatitis Reasons to Admit (6)
Encephalopathy (altered MS)
Hypoxemia
Tachycardia with hypotension
HCT >50 (dehydration)
Oliguria
Azotemia
Ranson's Criteria for Necrotizing Pancreatitis (3 or more of 6)
Age >55
WBC >16000
Blood Sugar >200
Lact Dehydrogenase >350
AST >250
Low S. Calcium
Complications of Acute Pancreatitis (4)
ARDS
Necrotizing pancreatitis
Chronic pancreatitis/malabsorption
Pancreatic Pseudocyst (late)
Late stage complication of Acute Pancreatitis
Pancreatic Pseudocyst
Pancreatic Pseudocyst Tx
Monitor or drain percutaneously or via EGD
#1 cause of Chronic Pancreatitis
Chronic ETOH abuse
Dx of Chronic Pancreatitis
CT of abdomen to look for cacifications
Chronic Pancreatitis Tx
Pain Mangagement
Low fat diet
No ETOH
CCK
Pancreatic enzymes
Most common site of Pancreatic Cancer
Head
Painless jaundice
Pancreatic Cancer
Pancreatic Cancer Tumor marker
CA 19-9
2 Liver Function Tests
Albumin
Coagulation Factors (PT/INR)
4 Liver Enzyme Tests
AST
ALT
AlkPhos
GGTP/5'nucleotidase
What ALT/AST tests indicate
Elevated in hepatocellular inflammation or destruction/necrosis
Test for bone or liver enzymes
AlkPhos
How to differentiate AlkPhos elevation of liver from bone
Elevated AlkPhos with elevated GGTP/5'nucleatidase
Copper overload
Wilson's Disease
Iron overload
Hemochromatosis
Arthralgias, hepatomegally, gray skin, cardiomegally, conduction disorders, DM, ED
Hemochromatosis
Increased % transferrin sat
Hemochromatosis
Hemochromatosis Tx
Weekly phlebotomy
Kay-Fleischer ring on eye exam
Wilson's Disease
Wilson's Disease Tx
Penicillamine
ALT>AST (+20x elevated)
Viral Hepatitis
Most common Hep in US
Hep A
Hep A transmission
Fecal-oral
(foreign travel)
Hep A: acute or chronic?
Acute
Immunoglobin in acute Hep A infection
IgM
Immunoglobin suggesting immunity in Hep A
IgG
Immunoglobin pneumonic
IgM is up when you are Miserable
IgG is up when it is Gone
Hep B transmission
Blood
Hep that is major risk factor for Hepatocellular Cancer
Hep B
Hep that is easier to transmit sexually: Hep B or C?
Hep B
Hep more likely to become chronic: Hep B or C?
Hep C
Hep A Tx
None
Avoid ETOH/drugs metabolized by liver
Heps that have vaccine
Hep A and B
Indicates Hep B is actively replicating
HBsAg
(surface antigen)
Indicates Hep B immunity
AntiHBsAg
(surface antibody)
Indicates past Hep B infection
AntiHBcAg
(core antigen)
Indicates able to transmit Hep B infection
HBeAg
(open envelope)
Indicates unable to transmit Hep B infection
AntiHBe
(closed envelope)
Hep that can only replicate if HepBsAg is present
Hep D
Most common blood-borne infection
Hep C
Leading cause of chronic liver failure
Hep C
Most common indication for liver transplant
Hep C
When must you screen for Hep C (3)
Life insurance exams
Employment screenings
Prenatal care
Hep C screening
EIA
Hep C Dx Confirmation
If EIA positive, RIBA to confirm
Hep C RNA used to establish Hep C chronicity and for theapeutic management
Viral load testing
Used to stage inflammation/fibrosis of Hep C
Liver Bx
Excludes pts from Hep C Tx (3)
Major psych illness
Ongoing ETOH or substance abuse
Comorbid conditions (ie, immunocompromised)
Hep C Tx
Pegylated interferon plus ribavirin
Most common cause of cirrhosis
Alcoholic Hep
AST>ALT (rarely above 300)
Alcoholic Hep
Alcoholic Hep Tx
Abstinance
Mildly elevated AST/ALT and AlkPhos levels
Nonalcoholic Fatty Liver
ALT>AST
Nonalcholic Fatty Liver
AST/ALT >2.0
ETOH
Nonalcoholic Fatty Liver Dx
One of exclusion
Liver biopsy confirms
Nonalcoholic Fatty Liver Tx
Weight loss
Fat restriction
Exercise
Most common metastatic Cancer
Hepatocellular Neoplasm
Origin of Hepatocellular Neoplasns
Lung
Colon
Breast
Prostate
Hepatocellular carcinoma Tumor Marker
AFP
Small Bowel Diseases (3)
Inflammatory Bowel Diseease (Crohn's)
Obstruction
Mesenteric Ischemia
Crohn's v. UC: Transmural, so causes inflammation, strictures, and fistulas
Crohn's
Crohn's v. UC: Superfiscial, friable
UC
Crohn's v. UC: Typically spares the rectum
Crohn's
Crohn's v. UC: "skip lesions"
Crohn's
Crohn's v. UC: cobblestoning
Crohn's
Crohn's Dx
Colonoscopy
(Biopsy is gold standard)
Crohn's v. UC: string sign
Crohn's
Crohn's v. UC: Malabsoption of B12 and fat
Crohn's
Crohn's cancer risk
Small bowel adenocarcinoma
Crohn's Colitis monitoring
Colonoscopy after 7-8 years and then every 1-2 years
Crohn's v. UC: surgery cures
UC
Crohn's v. UC: Surgery treats complications, but does not cure
Crohn's
Crohn's 1st line maintanence Tx
Aminoslicylates/5ASAs (mesalamine)
Crohn's 2nd line maintanence Tx
Immunomodulators (azothioprine, 6mp)
Crohn's 3rd line maintanence Tx
Biological Therapies (remicade, humira, cimzia)
Crohn's flare Tx
Corticosteroids (prednisone, entocort)
Crohn's infection Tx
Antibiotics (flagyl, xifaxin)
Crohn's Tx (5)
Aminosalicylates/5ASAs
Corticosteriods
Immunomodulators
Antibiotics
Biological Therapies (-mab)
Mesalamine
Prednisone, Entocort
Azothioprine, 6mp
Flagyl, Xifaxin
Remicade, Humira, Cimzia
Immunomodulators (Azothioprine, 6mp) Warnings
Pancreatitis risk
Check LFTs/CBC every 90 days
Poor absorption in Crohn's (2)
B12
Fat
Air/fluid level on upright KUB
Small Bowel Obstruction
Most common cause of SBO
Adhesions
SBO Tx
Nasogastric tube
Bowel rest
Surgery if not resolved
>50 yo with h/o attherosclerotic heart disease causeing hypoperfusion of bowel vasculature
Mesenteric Ischemia
Sudden, severe, abdominal pain that is out-of-proportion
Positive hemoccult
Pain is post-prandieal
Mesenteric Ischemia
Mesenteric Ischemia Dx
Angiography
Mesenteric Ischemia Tx
Angiography
Surgery
Malabsorption Syndromes (3)
Celiac Sprue
Pancreatic Insufficiency
Short Bowel Syndrome
Loss of absorptive surface results in malabsorption
Abnormal immune response to gluten
Celiac Sprue
Celiac antibodies (2)
IgA endomysial antibiody
IgA tTG antibody
Celiac gold standard Dx
Mucosal biopsy showing villous atrophy and blunting of villi duodenum
Villous atrophy and blunting of villi duodenum
Celiac
Celiac Malabsortption Deficiencies (4)
Fe
Ca
Vit D
B12
Dermatitis herpetiformis
Celiac derm condition
Pruritic paluovesicles over extensor surfaces and the trunk and neck
Dermatitis Herpetiformis
Clue to Celiac
Celiac Tx
Gluten free diet
No BROW
Barley
Rye
Oats
Wheat
Celiac pts can eat
CRAP
Corn
Rice
Arrowroot
Potatoes
Secondary to reoval of small intestine
Short Bowel Syndrome
More than 50 cm of ileum is resected
Short Bowel Syndrome
Short Bowel Syndrome Tx
Monthly B12 Injections
Early symptoms include poorly localized periumbilical abdominal pain
Pain localizes to the right local abdominal quadrant
Appendicitis
McBurney's
Appendicitis
Appendicitis Differential Work-up
Pelvic US
Leukocytosis with PMN predominant
Appendicitis Dx
CT
Large Bowel Diseases (7)
Constipation/fecal impaction
UC
Diverticulitis
Diverticulosis
Toxic Megacolon
Large Bowel Obstruction
Colon Cancer
Meds that cause Constipation (6)
Narcs
Diuretics
CCBs
Calcium supplements
Fe supplements
Cholestyramine
Structural cause of constipation
Colorectal masses
Systemic causes of constipation (4)
Hypothyroidism (Toxic Megacolon)
DM
Parkinson's
MS
Fecal Impaction Differential Work-up
DRE
Fecal Impaction Tx
Disimpaction
Crohn's v. UC: LLQ pain and bloody diarrhea
UC
UC Dx
Colonoscopy and biopsy
Crohn's v. UC: inflammation begins in distal rectum and spreads proximally
UC
Crohn's v. UC: Continuous lesion
UC
Crohn's v. UC: Sharp demarcation between normal mucosa and ulcers
UC
Crohn's v. UC: Rectum is always involved
UC
Waking up in middle of night for BM
Crohn's or UC
Crohn's v. UC: Erythema, friable mucosa
UC
Crohn's v. UC: Crypt abscess, architecture distortion
UC
UC complications (3)
Toxic Megacolon
Perf
Colon cancer
UC Cancer Surveilance
Colonoscopy yearly after 7-8 years
UC Tx (5)
Aminosalicylates/5ASA
Corticosteroids (prednisone taper)
Immunosuppressives (azothrioprine/6mp)
Tumor necrosis factor/biologics (Infliximab)
Surgery
Only curative UC Tx
Surgery
Believed to be due to chronic low-fiber diets
No infection
Diverticulosis
Diverticulosis Tx
Avoid popcorn
Eat high fiber diet
Most common cause of lower GI bleeds in >50yo
Diverticular hemorrhage
Acute, painless, large volume maroon or BRB in patients >50 yo
Diverticular hemorrhage
Micro-perf of a diverticulum resulting in acute infection of bowel wall
Diverticulitis
LLQ pain and mass
Fever
Leukocytosis
May see constipation leading up to attack
Diverticulitis
When is CT necessary in diverticulitis?
If symptoms don't resolve in 2-4 days on meds
Diverticulitis No-no's
Barium enema
Scoping acutely
Elderly diverticulitis Tx
IV Metronidazole and Cipro for 10-14 days
(broad spectrum and anaerobic coverage)
2+ Diverticulitis Attacks
Surgical consultation for elective resection (typically sigmoid)
BRB per Rectum imaging (3)
Anoscope or DRE at minimum
Rigid/Flex sig
Colonoscopy is both Dx and Tx
What precedes most colon cancer
Adenomas
Microcytic anemia + >50
Colon Cancer
Weight loss and obstuction
Late stage symptoms of colon cancer
Second most common cause of cancer death
Colon cancer
Leading cause of cancer death
Lung cancer
Peutz-Jeghers syndrome
Familial colon cancer
Associated with colorectal cancer, endometrial cancer, ovarian cancer
HNPCC
Colon Cancer Screening
Annual FOBT >50yo
Sigmoidoscopy with polyp removal every 5 years >50 yo, plus yearly FOBT
Barium enema every 5-10 years
Colonoscopy every 10 years
Annual FOBT rules
No red meat for three days
Three consecutive stools
First degree relative with cancer >60 screening
Age 40 (colonoscopy preferred)
First degree relative with cancer <60 screening
Screen ten years younger than age at dx
Colonscopy every 3-5 years
IBD patient cancer screening
Colonoscopy 8 years after diagnosis
Familial adenomatous polyposis cancer screening
Sig at age 12 (genetic screening after age 10)
HNPCC cancer screening
Genetic testing available
Tear at rectal sphincter
Dyschezia
Hematochezia
Anal Fissure
Anal Fissure Dx
DRE with equisitie tenderness posterior midline position
Anal skin tag
Dilations of the vascular bed
Painless hematochezia
Hemorrhoids
Above Dentate line
Internal Hemorrhoids
Below Dentate line
External Hemorrhoids
Chronic >3mo lower GI symptoms
Relieved with defecation
Change in frequency of stool
Change in stool caliber
IBS
Not bloody, not nocturnal passage of mucosy stool
IBS
Night blindness
Poor wound healing
Vitamin A
ETOH
BeriBeri
High output CHF/Wernicke's encephalopathy
Thiamine (B1)
Pellagra
Dermatitis
Dementia
Diarrhea
Niacin (B3)
Anemia, Peripheral neuropathy
Pyridoxine (B6)
Osteomalacia
Vit D
Scurvy
Vit C
Bleeding dyscrasia
Vit K
What vitamins are fat soluble?
D, E, A, K
Vitamin B12 absorption
Stomach
Small Intestines
Pernicious anemia
Vitamin B12
Vitamin A absorption
Small intestines
Vitamin B1 absorption
Upper small intestines
Vitamin B3 absorption (niacin)
Stored in liver
Absorbed in intestines
Vitamin B6 absorption
Jejunum
Illium
Protrusion of viscus through an opening in the wall in which it is contained (peritoneum sac)
Hernias
Through the internal inguinal ring
Indirect Inguinal Hernia
Through the back wall of the inguinal canal
Direct Inguinal Hernia
Protrusion through the femoral ring
Femoral Hernia
Infants; adults (acquired)
Type of hernia
Umbilical Hernia
History of previous surgery
Type of hernia
Incisional Hernia
Stomach/intestines protrudes into chest cavity through diaphragm defect
Hiatal Hernia
When Hernias recquire emergent repair
Incarcerated
Strangulated
Bright red blood in vomit
Coffee ground emesis
Hematemesis
Black tarry stool
Melena
Upper GI Dx
Endoscopy
Upper GI Tx
Endoscopy
Causes of UGI bleeding (6)
PUD
Varices
NSAID gastropathy
Mallory-Weiss Tear
Vascular Ectasias and AVMs
Boerhaave's syndrome
Boerhaave's syndrome
Ruptured esophagus
Bleeding that occurs below the Ligament of Treitz
Anemia
Hematochezia
Lower GI Bleeding
Where most Lower GI bleeding occurs
Colon
Causes of Lower GI Bleed in pts <50yo (3)
Infectious colitis
IBD
Anorectal disease (fissures/hemorrhoids)
Causes of Lower GI Bleed in pts >50 (7)
Diverticulosis bleed
Neoplasm
Vascular ectasias
IBD
Anorectal disease
Ischemic colitis
Unknown
Occult GI Blood Loss in pts >40-45 (6)
Neoplasm
Vascular ectasias
PUD
Infectious diseases
NSAIDs
IBD
Healthy 35yo nonsmoker/drinker with dyspepsia comes in failing tums daily. No anemia, wt loss, overt GI blood loss, family history, or regular NSAID use
Do you:
A. Send for EGD
B. Place on PPI daily and check back in one month
C. Order 24 hr pH monitoring study
D. Send for barium swallow
B
59yo male with ETOH/tobacco history presents with rare episodes of new solid food dysphagia. No wt loss, overt GI blood loss, anemia, GERD symptoms, oor family histor. He isn't too concerned as it only occurs every other week and resolves.
What sould be the best next step:
A. Place on PPI and follow up in one month
B. Order a barium swallow study
C. Plan for EGD
D. Treat him for presumed Barrett's Esophagus on PPI daily and follow up in one year
C
Checking for squamous cell esophageal carcinoma
65yo male with recent regurgitation of food in am upon awakening. Also complains of coughing with PO intake, occasionally food becoming stuck as well. Has new infiltrate on CXR.
The next best step would be:
A. Place on PPI and F/U in one month
B. Plan for EGD
C. Arrange barium swallow/esophagram
D. Arrange for esophagram first, followed by EGD
D.
Zenker's
56yo female with h/o arthritis presents with DOE, black tarry stools, hgb 6/hct 15 and using NSAIDs regularly.
You recommend:
A. EGD
B. D/C unnecessary NSAIDs
C. Transfusion
D. Add PPI if NSAID is required
E. All of the above
E
Overweight healthy 48yo male with following labs: AST/ALT normal, total bili 2.8, direct bili normal.
From this you suspect:
A. Pt is a drinker
B. Pt has fatty lifver
C. Pt has Gilbert's disease
D. Pt could have gallstone
C
19yo overweight healthy female with 2 yr h/o 4-5 nonbloody BMS daily (occasionally nighttime), abdominal cramping; wt loss and family history of thyroid and rheumatoid in her mother.
Your next best step is:
A. Place on high fiber and manage symptoms (antispasmotics, antidiarrhea meds)
B. Check blood work (TSH, CBC, Sed Rate, CRP, Celiac markers)
C. Arrange for colonoscopy
D. Both B and C
D
29yo male with UC, c/o fatigue, jaundice, pruritis, fatigue, and elevated LFTs, Alk Phos and total bili
You suspect:
A. Primary Biliary Cirrhosis
B. Autoimmune hep
C. Hemocromatosis
D. Primary Sclerosing Cholangitis
E. Fibrotic disease of the intra/estrahepatic biliary ducts
D and E
(same)
38yo w infertility, iron deficiency anemia, abd pain and irregular bowel habit.
You suspect:
A. Lactose Intolerance
B. IBS
C. Celiac sprue
D. UC
E. Crohn's
C
Positive AMA and Alk Phos in 50yo woman with fatigue, jaundice, pruritis.
A. Primary Billiary Cirrhosis
B. Primary Sclerosing Cholangitis
C. Autoimmune Hep
D. Wilson's Disease
E. Cholangiocarcinoma
A
ETOH binge drinking 16yo woman gives h/o multiple episodes of bilious vomit followed by painless hematemesis. Hemodynamically stable.
You suspect:
A. Borrhaave's Esophagus
B. Barrett's Esophagus
C. Mallory-Weiss tears
D. Esophageal Varix
E. Infectous Esophagitis
C
25yo female wt lifter with 2 new episodes of painless hematochezia this week. No unexplained wt loss, change in bowel habit, family hx or abd pain.
You first:
A. Provide info about fiber and hemorrhoids. F/U in office in one month
B. Arrange for flex sig/colonoscopy
C. DRE
C
59yo woman with previous finding of diverticular disease on colonoscopy last year presents with new onset LLQ abd pain, low grade fever, but otherwise appears healthy. No prior history of similar presentation.
Your best management is:
A. Arranging for colonoscopy
B. Arrange for barium enema
C. Arrange for surgical referment
D. Place pt on cipro and metronidazole
E. Advise liquid diet followed by bland diet with later recs for high fiber diet.
F. Both D and E
F