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16 Cards in this Set

  • Front
  • Back
Duration of action is divided into
Pulpal Hard tissue
Soft tissue total
What does the duration depend on?
1. individual variation
2. technique
3. tissue status (vascularity, ph)
4. anatomical varation
5. type of injection - infiltration or nerve block
What are the doses for local anesthetic drugs?
Presented in terms of mg/kg or mg/lb.

Max dose: local anesthetic blood level just below the threshold for an overdose reaction.
-hyporesponders
-hyperresponders
What are 3 categories of patients with potentially increase risk?
-small child
-elderly individual
-medically compromised patient
Describe procaine
Ester: provides essentially no pulpal anesthesia and 15-30 minutes soft tissue anesthesia.
Produces the greatest vasodilatation
No longer available
High incidence of allergy
Propoxycaine
Ester- its not available alone because of its high toxicity.
Ravocaine
Combination of Procaine + Propoxycaine
Not available since January 1996.
It was useful when amides were contraindicated.
Benzocaine
Ester-type topical local anesthetic for temporary relief of pain associated with toothache, minor sore throat pain and canker sore.
Lidocaine
use in
1. dental
2. medical
Max dose?
Dental: Amide-type injectable local anesthetic and topical local anesthetic


Max dose: 300 mg. 4.4 mg/kg or 2 mg/lb
Medical: Local anesthetic and acute treatment of ventricular arrhythmias from myocardial infarction.
Allergies to amide local anesthetics is virtually nonexistent
Describe the duration of anesthesia for lidocaine 2%
Pulpal 5-10 min
Soft tissue 60-120 min

Probably not the best anesthetic to use without a vasoconstrictor.
Duration of anesthesia for lidocaine 2% with Epi 1:100,00
Pulpal 60 min soft tissue 3-5 hr


Need the one that's more concentration for better vasoconstriction, so use 1:50,000 but think about cardiac patients.
Mepivicaine
Dental: Amide-type anesthetic used for local infiltration anesthesia; injection near nerve trunks to produce nerve block.
Produces slight vasodilatation
Malamed recommends a maximum dosage of 2mg/lb or 4.4mg/kg. (max: 300mg)
Mepivicaine
Pulpa 20-40 min
Soft tissue 2-3 hr
Prilocaine
Dental
Metabolism
Dental- Dental: Amide-type anesthetic used for local infiltration anesthesia; injection near nerve trunks to produce nerve block.
Metabolism: hydrolyzed in the liver to orthotoluidine and N-propylalanine.(orthotoluidine can induce methemoglobinemia)
Maximum Recommended Dose: 2.7mg/lb or 6.0mg/kg to a maximum of 400mg

4% prilocaine 5-10 min pulpal anestheisa
Soft tissue: 60-120 min


Cyanosis, graying, bluish lips are signs of methemoglobinemia. Methylene blue 1% solution administered over 15 min period.

Its a relative contraindication to those who have methemoglobinemia.
4% Septicaine with 1:100,000 epi
3.2 mg or 7.0 mg/kg max dose in adults; 2.27 mg/lb or 5.0 mg/kg max dose in kids. 500 mg max

Pulpal: 60-75 min
Soft tissue: 3-6 hr
0.5% bupivicaine with 1:200,000 epi
1.3 mg/kg or 0.6 mg/lb 90 mg max
Pulpal: 90 - 180 min
Soft tissue: 4-9 hr