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67 Cards in this Set

  • Front
  • Back

leak ion channel

channels that randomly open and close to let ions in or out

ligand-gated channel

channel that opens in response to a ligand binding to it

voltage-gated channel

channel that opens in response to a change in membrane potential

graded potential

a small deviation from the resting membrane potential that makes the membrane more or less polarized

hyperpolarizing

resting membrane potential becomes more negative

depolarizing

resting membrane potential becomes less negative

summation

the process by which graded potentials add together

threshold

when depolarization reaches a certain level, it fires an action potential

all-or-none pricipal

action potential either fires or does not, there is no in between

refractory period

the time a cell can't fire another action potential even if threshold is reached

local anesthetics

drugs that block pain, block the opening of voltage-gated Na+ channels

saltatory conduction

occurs in myelinated axons, special mode of action potential propogation

presynaptic neuron

nerve cell that carries a nerve impulse towards a synapse

postsynaptic neuron

carries a nerve impulse away from a synapse

synaptic cleft

space between presynaptic and postsynaptic neurons that's filled with interstitial fluid

postsynaptic potential

graded potential, converts electrical signal into a chemical signal

EPSP

a neurotransmitter that causes depolarization of the postsynaptic membrane, brings closer to threshold

IPSP

a neurotransmitter that causes the hyperpolarization of the postsynaptic membrane

spatial summation

summation of post-synaptic potentials in response to stimuli released at different locations at the same time

temporal summation

summation that occurs at different times

acetycholine

an excitatory and inhibitory neurotransmitter, a small molecule

GABA

inhibitory neurotransmitter, amino acid, small group

catecholamines

dopamine/epinephrine, have amino group and a catechol ring

nitric oxide

NO, excitatory, gas, secreted in brain, spinal cord, adrenal glands, and penis nerves

agonist

an agent that binds to receptors and enhances or mimics the effect of a natural neurotransmitter

antagonist

an agent that binds to and blocks neurotransmitter receptors

neural divergence

one presynaptic neuron influences several postsynaptic neurons

neural convergence

several presynaptic neurons synapse with a single postsynaptic neuron

plasticity

the capability to change based on experience

excitotoxicity

destruction of neurons through prolonged activation of excitatory synaptic transmission

SSRIs

drugs that provide relief from some forms of depression

spinal tap

procedure to get CSF out of the spinal cord, to test/diagnose or introduce medicine

posterior root

only sensory axons, conduct nerve impulses from receptors in the skin into CNS

anterior root

contains axons of motor neurons, conduct nerve impulses away from the CNS to effectors

posterior gray horns

cell bodies and axons of interneurons as well as axons of incoming sensory neurons

anterior gray horns

contain somatic motor nuclei, provide nerve impulses for contraction of skeletal muscle

lateral gray horns

present only in thoracic and upper lumbar, regulate cardiac, smooth, and glands

sensory tracts

axons that conduct nerve impulses toward the brain

motor tracts

axons that carry nerve impulses away from the brain

mixed nerve

a nerve that has motor and sensory tracts

posterior ramus

serves the deep muscles and skin of the posterior surface of the trunk

anterior ramus

serves the muscles and structures of the upper and lower limbs and the skin of the lateral and anterior surfaces of the trunk

plexus

axons that do not go directly to the body structures they supply, instead form networks

intercostal nerves

anterior rami of spinal nerves that do not enter into the formation of plexuses

dermatome

the area of the skin that provides sensory input to the CNS via one pair of spinal nerves or the trigeminal

direct motor pathways

convey nerve impulses that originate in the cerebral cortex and become voluntary movements

indirect motor pathways

convey nerve impulses from the brain stem to cause automatic movements and help coordinate body movements with visual stimuli

somatic reflexes

involve contraction of skeletal muscles,

autonomic reflexes

generally not consciously percieved, responses of smooth, cardiac, and glands

integrating center

a single synapse between a sensory neuron and a motor neuron

muscle tone

the small degree of contraction present while the muscle is at rest

tendon reflex

a feedback mechanism to control muscle tension by causing muscle relaxation before muscle force makes tendons tear

contralateral

sensory impulses enter one side of the spinal cord and motor impulses exit on the opposite side

paraplegia

paralysis of both lower limbs

hemiplegia

paralysis of the upper limb, trunk, and lower lib on one side of the body

quadriplegia

paralysis of all four limbs

hemisection

a partial transection of the cord on either the right or the left side

myelitis

inflammation of the spinal cord

neuralgia

attacks of pain along the entire course or a branch of a sensory nerve

paresthesia

an abnormal sensation such as burning, prickling, tickling, or tingling resulting from a disorder of a sensory nerve

brain stem

continuous with the spinal cord and consists of the medulla oblongata, pons, and midbrain

diencephalon

superior to the brain stem, consists of the thalamus, hypothalamus, and epithalamus

brain ventricles

four CSF-filled cavities within the brain

choroid plexuses

networks of blood capillaries in the walls of the ventricles

interventricular foramina

CSF flows into the third ventricle through two narrow, oval openings called

hydrocephalus

caused by elevated CSF pressure, can cause nerve damage

arachnoid villi

fingerlike extensions of the arachnoid mater that project into the dural venous sinuses