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16 Cards in this Set
- Front
- Back
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fluid entering loop of henle has osmolarity of
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300mOsm/L = to glomerular filtrate
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fluid that leaves thick ascending limb (tonicity)
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hypotonic
this is the diluting segment |
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during antidiuresis, what are levels of ADH?
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high (makes late dist tuble and CD permeable to water)
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urea reabsorb in CDs is (high/low) during antidiuresis
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high
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ADH increases urea permeability where
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inner medullary collecting ducts ([urea] is very high here, so increased permeability allows urea to diffuse out of tubular fluid into inner medulla/papilla)
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countercurrent exchange in vasa recta (active/passive)
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passive
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asend limb of vasa recta: which direction do solutes and water diffuse? effect on osmolarity of bld
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solutes diffuse out
water diffuses in decreases osm. of bld |
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V2 receptors (AQP2): found where? in what cells? What areas of nephron
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found in basolat. memb
of principle cells in late dist tubule and CD |
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central diabetes inspidus: describe ADH
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absent
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nephrogenic diabetes inspidus
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resistance of principle cells to ADH
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free water clearance (CH20) is
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amount of water that must be +/- to urine to make it isosmotic w/plasma
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if ADH is low, what happens to free water produced in diluting segments?
tonicity of urine (compared to pl) |
free water = excreted (positive fre water)
urine = hyosmotic |
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if ADH is high, what happens to free water produced in diluting segments?
tonicity of urine (compared to pl) |
free water = reabsorbed by CD
no free water excreted (neg) urine = hyperosmotic |
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if urine is hyposomtic to pl, CH2O is (neg/pos)
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pos
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if urine is hypersomtic to pl, CH2O is (neg/pos)
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neg
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SIADH
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ADH is excreted when it should be suppressed
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