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31 Cards in this Set

  • Front
  • Back
Most common bugs to cause Sinusitis
Mainly Viral
Strep pneumonia
H. influenza
M. Catarrhalis
Treatment options for Sinusitis
Symptomatic Treatment:
hydration, analgesics, antipyretics, saline irrigation, and intranasal corticosteroids

Do NOT use oral decongestants and/or antihistamines

1st Line: Augmentin
2nd Line: Doxycycline, Respiratory FQ
Resistant: high dose Augmentin

Do NOT use:
Bactrim
Macrolides
2nd and 3rd gen Cephalosporins
Signs and Symptoms Requirement before treatment for Sinusitis?
S/S Sinusitus

1. Persistent/not improving (>10 days)
2. Severe (>3-4 days)
3. Worsening (>3-4 days)
Risk factors for Resistance
1. <2 or >65 yoa; daycare
2. ABX within 1 month
3. hospitalization in past 5 days
4. Comorbidities
5. Immunocompromised

Treatment duration with risk of resistance:
7-10 days of ABX
Organisms causing Acute Bronchitis
Bordetella pertusis
Mycoplasma pneumonia
Chlamydia pneumoniae
Organisms causing Chronic Bronchitis
H. influenza
H. parainfluenzae
M catarrhalis
Pneumococcus
When do you treat Acute Bronchitis?

How do you treat it?
NO antibiotics or mucolytics

Supportive care:
antipyretics, fluids, inhaled bronchodilators

ABX if...
1. Persistent fever or s/s >4-6 days
2. Predisposed pts (elderly, immunocompromised)
Difference between Acute and Chronic Bronchitis
Acute:
BORDETTELA PERTUSSIS, MYCOPLASMA PNEUMONIA, CHLAMYDIA PNEUMONIA
sore throat, malaise, HA
>5 days to weeks
Non productive or productive cough
CXR is clear

Chronic:
H. INFLUENZA, H. PARAINFLUENZAE, M. CAT, PNEUMOCOCCUS
Coughing up of sputum on most days for at least 3 months each year for 2 consecutive years
Excessive, thick, purulent
CXR is clear, but Barrel chest
What is considered moderate Bronchitis and how do you treat it?
Moderate (> or = 2 symptoms without risk factors)
-increased dyspnea
-increased sputum production
-increased sputum purulence

Extended Spectrum Cephalosporin:
Cefdinir
Cefprozil
Cefuroxime

Advanced macrolide:
Azithromycin
Clarithromycin

Tetracyclines:
Doxycycline
What is considered severe Bronchitis and how do you treat it?
Severe (> or = 1 risk factor- obviously w/ symptoms)
Age > or = 65 yo
FEV < or = 50%
4 episodes of AECB/ year
1 or more comorbidities

Treatment:
High dose Augmentin
Respiratory FQ
What characterizes the influenza?
ABRUPT ONSET OF SYMPTOMS:

High fever
Nonproductive cough
malaise
rhinitis
sore throat
MUSCLE ACHES
headaches

uncomplicated influenza lasts for 3-7 days
cough and malaise may last >2 weeks
When are you at risk of complications from the Influenza?
Morbidly obese
American Indian/ Alaska Native
Age <5 and >65
Chronic Conditions
Immunosuppression
Pregnant or Postpartum (2 weeks)
Age <18 with long term ASA
Resident of LTCF
What are the different types of Influenza and which one is predominate?
Predominate= Pandemic A (H1N1)

Others:
Seasonal A (H1N1)
Seasonal A (H3N2)
Influenza B
Who is indicated to receive the Influenza Vaccine?

What populations are most important to receive it?
All persons > or = 6 months of age

Children: 6 months- 4yrs
> or = 50 years of age
Chronic medial conditions
immunocompromised
Nursing home residents and chronic care facilities
Pregnant women
Age <18 receiving long term ASA therapy
Health care personnel
caregivers of high risk people
caregivers of children <5 and >50
American Indians/ Alaska Natives
BMI > or = 40
What is the difference between the TIV vs LAIV?
Trivalent Influenza Vaccine (TIV):
killed (can't cause influenza)
indicated for > or = 6 months of age
route is IM or intradermal (only 18-64 yo
Contraidicated if history of Guillain-Barre syndrome or if there is current fever

Live Attenuated Influenza Vaccine (LAIV):
Live
Indicated for ages 2-49
Intranasal
Contraindicated if pt has asthma, is immunodeficient, on long term ASA treatment, Guillain-Barre Syndrome, pregnant, current fever, or nasal condition that makes breathing difficult
What is the dosing for Zanamivir?
Zanamivir (Relenza) 10mg (2 inhalations) BID

initiate within 48 hours of onset of symptoms to be effective in immunocompetent patients
What is the dosing for Oseltamivir?
Oseltamavir (Tamiflu) 75mg PO BID

initiate within 48 hours of onset of symptoms to be effective in immunocompetent patients
Describe Community Acquired Pneumonia (CAP)
Not hospitalized or in LTCF for >14 days before onset

1. s. pneumoniae
2. m. catarrhalis
3. H. influenza
4. Mycoplasma pneumonia
5. Chlamydia pneumonia
6. Legionella
7. K. pneumonia
8. S. aureus
9. Pseudomonas aeroginosa

Viral:
10. Influenza A and B, H1N1
11. RSV (usually kids)

Treatment Duration for CAP= 5-7 days
Describe Aspiration Pneumonia (AP)
material from the stomach or URT into the LRT or oropharyngeal bacteria
Describe Hospital Acquired Pneumonia (HAP)
Occurs > or = 48 hrs after admission

Potential Pathogens needing only Limited Spectrum:
1. strep. pneumoniae (early onset)
2. H. influenzae (early onset)
3. MSSA
4. E. coli
5. K. pneumonia
6. Enterobacter sp
7. proteus sp
8. serratia marcescens

Potential Pathogens needing Broad Spectrum:
1. P. aeruginosa
2. K. pneumoniae
3. Acinetobacter sp

Oral Chlorhexadine may be helpful

Treatment Durations for HAP= 7-10 days
Describe Healthcare Associated Pneumonia (HCAP)
Any patient who has:
1. hospitalized for > or = 2 days in last 90 days
2. LTCF
3. received IV ABX
4. Chemotherapy
5. Wound care within past 30 days
6. attended a hospital or dialysis center
Describe Ventilator Associated Pneumonia (VAP)
Arises >48-72 hrs after endotracheal intubation
How to treat CAP?

Empiric Outpatient Healthy
Empiric Outpatient with co-morbidities
Empiric Inpatient no in ICU
Empiric Inpatient in ICU or incubated
Community Acquired MRSA
Empiric Outpatient Healthy- Advanced Macrolide OR Doxycycline; Alt. Respiratory FQ

Empiric Outpatient with co-morbidities- Macrolide + Beta-lactam OR Respiratory FQ

Empiric Inpatient no in ICU- Respiratory FQ OR IV beta lactam + Advanced macrolide OR doxycycline

Empiric Inpatient in ICU or incubated:
IV beta lactam OR
IV beta lactam + IV respiratory FQ OR
IV Aztreonam + IV respiratory FQ

Community Acquired MRSA:
Clindamycin OR
Vancomycin (but Gauthier says it doesn't go in lungs) OR
Linezolid
How to treat Aspiration Pneumonia
Same as normal coverage, but ADD Clindamycin
What is the most common cause of HAP?
Pseudomonas aeruginosa
What is the most common cause of VAP?
Pseudomonas aeruginosa
Early onset HAP is usually caused by
Streptococcus pneumoniae
H. influenza
HAP Limited Spectrum vs. HAP Broad Spectrum
Limited Spectrum:
Ceftriaxone
OR
Levofloxacin, Moxifloxacin, Cipro
OR
Ampicillin/sulbactam
OR
Ertapenem

Broad Spectrum:
(2 drugs)

Antipseudomonal cephalosporin OR Antipseudomonal carbapenem OR Antipseudomonal beta lactam/ beta lactam inhibitor

PLUS

Antipseudomonal FQ or AG
Used to treat HA-MRSA pneumonia
Linezolid OR Vancomycin
Used to treat Legionella pneumonphila pneumonia
Macrolide OR FQ
What are the Guidelines for Pneumococcal Vaccine?
1. > 65 yoa

2. < 65 yoa w/...
chronic cardiovascular, pulmonary, renal, or liver disease
diabetes mellitus
cerebrospinal fluid leaks
alcoholism
asplenia
immunocompromising conditions/ medications
native america/ alaska natives
long term care facility residents

3. Current Smoker

4.One time re-vaccination after age 65 if last vaccine given longer than 5 years ago