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33 Cards in this Set
- Front
- Back
Bentyl
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Dicyclomine
caps- 10mg tabs- 20mg syrup- 10mg/tsp inj Use: IBS (irritable colon, spastic colon, mucous colitis) Counsel: Take 30-60 minutes before meals MOA: Antispasmodic/ Anticholinergic; Blocks ACH at the cholinergic (muscarinic) receptor of the gut Similar to Levsin |
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Donnatal
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Belladonna & Phenobarbital
Tabs (IR)- 16.2 mg PB/ dose Elixir- 16.2 mg PB/ TSP Extentabs (ER)- 3X the IR= 48.6 mg Use: IBS and related problems Phenobarbital is a calming agent= drowsiness (NO Alcohol) DI: Strong CYP-450 INDUCER |
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Librax
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Clindinium/ chlordiazepoxide
Caps- 2.5mg/ 5mg Anticholinergic & Benzodiazepine (NO ALCOHOL) Caution: may be habit-forming; BPH (decreased urine flow) |
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Tagamet and Tagamet HB
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Rx- Cimetidine tablets- 300, 400, 800mg
Rx- Cimetidine soln- 300mg/ tsp OTC- Cimetidine tabs- 200mg MOA: H2 Receptor Antagonist Antacids decreases cimetidine's absorption (only H2 receptor antagonist that chelates) DI: Theophylline, Plavix, Coumadin (Cyp blocker) Dosed frequently CAUTION: Breast swelling/ Gynecomastia |
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Zantac
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Ranitidine tabs- 150, 300mg
Ranitidine Effervescent tabs- 25mg Ranitidine liquid- 75mg/ tsp Ranitidine OTC tabs- 75, 150mg MOA: H2 Receptor Antagonist Dose: BID or HS (6 PM), as well as prn Effervescent tabs are for infant or child in > 5mL of water Therapeutic Dose= high Maintenance Dose= low |
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Pepcid, Pepcid ODT, Pepcid AC, and Pepcid Complete
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Rx- famotidine tabs- 20, 40mg
Rx- famotidine ODT- 20, 40mg Rx- famotidine susp- 40mg/ 5mL OTC- famotidine tab- 10, 20mg OTC- famotidine chewable tab plus CaCO3 and Mg(OH)2 MOA: H2 Receptor Antagonist Can be taken with Antacids Most commonly used H2RA, has few drug interactions |
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Axid and Axid AR
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Rx- Nizatidine caps- 150, 300 mg
Rx- Nizatidine soln- 150mg/ 10mL OTC- Nizatidine tabs- 75 mg MOA: H2 Receptor Antagonist Few drug interactions, Not advertised, not popular |
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Prilosec
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Rx- omeprazole Caps ER- 10, 20, 40 mg
OTC- omeprazole tabs ER- 20 mg MOA: Proton Pump Inhibitor-acid activated prodrug at pKa <4 DI: omeprazole inhibits conversion of Plavix (risk of clot) to active form and inhibits metabolism of warfarin (risk of bleed) PPI with fastest oral absorption |
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Zegerid
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Omeprazole with Sodium Bicarbonate
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Prevacid
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lansoprazole
caps ER and Solutabs- 15, 30 mg PO Susp ER granuls- 15, 30 mg IV powder (inj)- 30 mg OTC 24 hr capsule- 15 mg MOA: Proton Pump Inhibitor-acid activated prodrug at pKa <4 commonly used in combination with Amoxicillin or Amoxicillin and Clarithromycin for eradication of H. pylori (PrevPac) |
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Protonix
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pantoprazole
tabs ER, IV, and oral solution- 20, 40 mg MOA: Proton Pump Inhibitor-acid activated prodrug at pKa <4 PPI with least Drug interactions |
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Nexium
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esomeprazole
caps ER, IV, packets- 20, 40 mg MOA: Proton Pump Inhibitor-acid activated prodrug at pKa <4 Isomer of Prilosec |
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Aciphex
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Rabeprazole Tabs ER 20 mg
MOA: Proton Pump Inhibitor-acid activated prodrug at pKa <4 Can be taken with or without food |
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Dexilant
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Dexlansoprazole Dr Caps- 30, 60 mg QD
Isomer of Lansoprazole, 2-phase release MOA: Proton Pump Inhibitor-acid activated prodrug at pKa <4 |
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Carafate
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Sucralfate tabs- 1 gram
Sucralfate Susp- 1 gram/ 2tsp Aluminum Sulfated Sucrose Use: Duodenal ulcer; GI Band-AID Good for pregnant patients; no systemic absorption, only local Counsel: take with water, 60 min before meal; separate from other drugs (Al can chelate); Constipation Take 1 hr after meal for heart burn |
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Cytotec
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misoprostol tabs- 100, 200 mcg
MOA: Prostaglandin analog that increases GI mucus; mildly blocks acid secretion Use: Gastric ulcer; decreases risk of NSAID induced gastric ulcers Taken up to 4 times daily Unlabeled use: cervical ripening and labor induction; pregnancy termination Adverse Effect: Diarrhea Pregnancy (BBW) can induce contractions; Category X |
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Reglan
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metoclopramide
tabs- 5, 10 mg syrup- 5 mg/ tsp Injection- 5 mg/ mL MOA: Ach Agonist (GI prokinetic) and DA Antagonist (Antiemetic); facilitates Ach release from enteric neurons; stimulates GI peristalsis USE: diabetic gastropersis, symptomatic GERD, N/V SE: EPS- lip smacking, chewing, tardive dyskinesia and Diarrhea Caution: CNS depression; Ach agonist w/ DA antagonist effects (CI in Parkinson's patients) Do NOT take with Librax or Dicyclomine (seperate by a few hours) ODT= Metozolv 5mg or 10mg |
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Amitiza
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Lubiprostone caps- 8, 24 mcg
MOA: Activates Cl- channels, enhances intestinal fluid secretion USE: for irritable bowel syndrome with Constipation (IBS-C) |
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Compazine
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prochlorperazine
tabs- 5, 10 mg SUPP- 25 mg Injection Phenothiazine indicated for N/V treatment MOA: DA and Ach Antagonist EPS Potential |
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Tigan
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Trimethobenzamide
Caps- 300mg Inj (IM) Unkown MOA Moderately effective DESI drug (effecacy not proven) |
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Lomotil
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Diphenoxylate/ Atropine Sulfate
tab- 2.5/ 0.025 mg Liquid- 2.5/ 0.025mg/ tsp Use: Adjunct tx in the treatment of diarrhea Narcotic related to meperidine; inhibits peristaliss C-V Controlled Drug |
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Zofran
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Ondansetron
Tabs- 4, 8 mg PO soln- 4 mg/ tsp Inj soln- 2mg/ mL 5-HT3 receptor Antagonist- works peripherally no vagal nerve terminals and centrally in the CTZ |
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Kytril
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Ganisetron
tabs- 1 mg PO soln- 2mg/ 2 TSP MOA: Serotonin Antagonist Sancuso is Granisetron Transdermal System (one patch/ week) Over $400/ patch Useful in chemotherapy- associated nausea and vomiting |
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Asacol
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Mesalamine
ER Tabs- 400mg [2 TID] or higher HD tabs- 800mg MOA: 5- Amino salicylic acid (local action on gut mucosa. Anti-inflammatory) Indication: Crohn's , Ulcerative colitis |
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Pentasa
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Mesalamine
CR (ER) Capsules- 250, 500 mg [1 gram QID] MOA: 5- Amino salicylic acid (local action on gut mucosa. Anti-inflammatory) Capsule can be opened and sprinkled on food |
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Rowasa
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Mesalamine
PR Susp (Enema)- 4 grams/ 60 mL [HS] MOA: 5- Amino salicylic acid (local action on gut mucosa. Anti-inflammatory) Shake well. Lie on LEFT SIDE at HS. Insert PR, retain in rectum 8 hours |
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CANASA
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Mesalamine
Supp- 1000 mg [1 BID] MOA: 5- Amino salicylic acid (local action on gut mucosa. Anti-inflammatory) Retain in rectum 1-3 hrs |
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Lialda
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Mesalamine
ER tabs- 1.2 g [2-4 grams QD w/ a meal] MOA: 5- Amino salicylic acid (local action on gut mucosa. Anti-inflammatory) Once a day dosage |
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Dipentum
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Mesalamine
Caps (rarely used)- 250mg [4 BID] MOA: 5- Amino salicylic acid (local action on gut mucosa. Anti-inflammatory) Two 5-ASA molecules linked by AZO bond. Split by bacteria. ADR: Diarrhea |
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Azulfidine
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Sulfasalazine
tabs- 500 mg Entabs- 500 mg PRODRUG- mesalamine (5-ASA) and sulfapyridine MOA: acts locally in the colon to decrease the inflammatory response and systematically interferes with secretion by inhibiting prostaglandin synthesis USE: Ulcerative colitis and lower Crohn's disease Check for SULFA ALERGY Take with Water |
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Colazal
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Balsalazide
Caps- 750 mg [3 TID x 8-12 wks] For ACTIVE ulcerative colitis PRODRUG of 5-ASA and inert carrier |
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Entocort E. C.
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Budesonide
capsule- 3 mg (corticosteroid, glucocorticoid) 9 mg AM up to 8 weeks, then taper down to 6 mg for 2 weeks before d/c Crohn's Tx in ileum or ascending colon; anti-inflammatory drug (blocks inflammatory PGs) Taper down to reduce risk of adrenal insufficiency |
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Pancreaze or Creon
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Pancrelipase
Digestive enzymes: Amylase, lipase, protease Enzyme replacement tx for cystic fibrosis, chronic pancreatitis, pancreatic insufficiency, malabsorption, etc. Florida Negative Formulary: Illegal to interchange brand/ generci or brand/brand Must stay with one manufacturer. MUST ask patient what brand or generic product they are previously used |