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32 Cards in this Set

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What is Latanoprost?
Xalatan (Latanoprost)

Prostaglandin F2 analogue- increases outflow of aqueous humor through uveoscleral route

refrigerate

For Glaucoma or Ocular HTN

SE: Possible color change of iris to brown or dark
What is Bimatoprost?
Bimatoprost (Lumigan) 0.01% and 0.03%

Prostaglandin analog-increases outflow of aqueous humor through uveoscleral route

also used as Latisse for eyelash growth

For Glaucoma or Ocular HTN

SE: Hyperemia
What is Travatan-Z
Travatan-Z (Travoprost)- 2.5mL and 5 mL

Prostaglandin Analog-increases outflow of aqueous humor through uveoscleral route

for glaucoma or ocular hypertension

Note: contains NO Benzalkonium clhloride
What is Timolol Maleate?
Timolol Maleate (Timoptic)- 0.25% and 0.5%

MOA: lowers IOP by decreasing the rate of aqueous production

non-selective Beta Blocker; use BID until IOP is maintained then change to QD

CI: COPD, Asthma, Cardiac failure, 2nd or 3rd degree AV block, sinus bradycardia, cardiogenic shock

Counsel: Avoid anticholinergics

24 Hr formulation: Timoptic XE (Shake before using)
What is Timolol Hemihydrate?
Timolol Hemihydrate (Betimol) 0.5%

MOA: lowers IOP by decreasing the rate of aqueous production

CANNOT BE SUBSTITUTED FOR TIMOPTIC

non-selective Beta Blocker; use BID until IOP is maintained then change to QD

CI: COPD, Asthma, Cardiac failure, 2nd or 3rd degree AV block, sinus bradycardia, cardiogenic shock

Counsel: Avoid anticholinergics
What is Metipranolol?
Metipranolol (OptiPranolol) 0.3%

MOA: lowers IOP by decreasing the rate of aqueous production; non selective beta blocker

CI: COPD, Asthma, Cardiac failure, 2nd or 3rd degree AV block, sinus bradycardia, cardiogenic shock

Counsel: Avoid anticholinergics
What is Combigan?
Combigan (Brimonidine 0.2% and Timolol 0.5%) 5 and 10 mL

Alpha 2 agonist and beta blocker

MOA (alpha 2 agonist) : lowers IOP by decreasing production of aqueous humor and increases uveoscleral outflow

MOA (beta blocker): lowers IOP by decreasing the rate of aqueous production
What is Betoptic-S Suspension?
Betaxolol (Betoptic-S Suspension) 0.25%

beta 1 selective blocker

BID dosing

Less stinging and less likely to cause bronchospasm

Note: SHAKE WELL
What is Betoptic?
Betoptic (Betaxolol) 0.5%

beta 1 selective blocker
What is Betagan?
Betagan (Levobunolol) 0.25% and 0.5%

Longest acting non selective beta blocker (once or twice daily)

MOA: decrease production of aqueous humor

CI: COPD
What is Alphagan-P?
Alphagan-P (Brimonidine) 0.1% and 0.15%

MOA: alpha 2 agonist- decreases production of aqueous humor and increases uveoscleral outflow

Use TID (8 hours apart)
What is Diamox?
Diamox (Acetazolamide) 125 and 250mg tablets; 500 mg Sequels (long acting capsules)

MOA: Carbonic Anhydrase Inhibitor

Use: open angle glaucoma

Also indicated for symptoms of acute mountain sickness in climbers attempting rapid ascent, and adjunctive treatment of edema due to CHF, drug-induced edema, and types of epilepsy

Caution: Sulfa allergy
What is Neptazane?
Neptazane (Methazolamide) 25mg and 50mg BID-TID

MOA: carbonic anhydrase inhibitor which decreases bicarbonate ion concentrations in ocular fluid which decreases production of aqueous humor

Use: open angle glaucoma and acute mountain sickness

Caution: Sulfa Allergy
What is Trusopt?
Dorzolamide (Trusopt) 2%- TID

MOA: inhibits production of aqueous humor by inihbiting carbonic anhydrase
What is Cosopt?
Cosopt (Dorzolamide 2% and timolol 0.5%)

carbonic anhydrase inhibitor with non selective beta blocker

MOA: decreases production of aqueous humor

Used BID
What is Azopt?
Azopt (Brinzolamide) 1%

MOA: carbonic anhydrase inhibitor for open angle glaucoma

Used TID

Less stinging than Trusopt (dorzalamide 2%)
What is Pilocar?
Pilocarpine (Pilocar, Isopto Carpine) 1, 2, 3, 4%

Pilocarpine HS gel is 4% and used at night time

Use: Acute glaucoma and pre/post operative intraocular tension

MOA: Direct acting Miotic (contraction of ciliary muscle and pupil) to facilitate drainage and increase outflow by opening the trabecular meshwork

Used BID-TID-or QID (rarely QD)

SE: Brow-ach and diarrhea
What is Carbachol?
Carbachol drops- direct acting miotic; longer acting parasympathetic stimulant, or cholinergic agonist

comparable to Pilocar (Pilocarpine)
What is Salagen?
Salagen (pilocarpine) 5mg tablets

Used for treatment of dry mouth (TID)

Also available in 7.5mg
What is Phospholine Iodide?
Phospholine Iodide (Echothiophate Iodide) 0.125%

MOA: Cholinesterase Inhibitor (increase Ach); indirect acting cholinergic agonist (Miotic)

Powder and liquid must by mixed in pharmacy before dispensing

Unpleasant, fishy odor... this is normal

Available only by drop ship from Manufacturer

Miscellaneous product rarely used
What is Tobrex?
Tobrex (Tobramycin) 0.3% Solution and 3.5 g ointment

Use: Bacterial conjunctivitis

Aminoglycoside

Eye drops can be used in the ear, but not other way around
What is Tobradex?
Tobradex (Tobramycin 0.3% with dexamethasone 0.1%)

Use: Bacterial conjunctivitis, corneal abrasion, uveitis

MOA: Anti-Inflamatory plus antimicrobial (AG)

TobraDexST (0.3%/0.5%)
What is Bleph-10?
Bleph-10 (Sulfacetamide ophthalmic) 10% solution

USE: Bacterial infections, chlamydial conjunctivitis

Caution: Sulfa Allergy
What is Erythromycin Ophthalmic Ointment?
Erythromycin Ophthalmic Ointment 0.5%- 3.5 g tube

USE: Bacterial infections, chlamydial conjunctivitis

Caution: case report of patient taking warfarin with INR that raised to 8.5
What is Ciloxan?
Ciloxan (Ciprofloxacin) .3% solution or 3.5 g tube

MOA: inhbits bacterial DNA gyrase

Use: superficial ocular infections

Compare to Ocuflox (Ofloxacin) and Vigamox (Moxifloxacin)
What is AzaSite?
AzaSite (Azithromycin) 1% Solution

Use: bacterial conjunctivitis in patients 1 yr of age and older caused by....

CDC coryneform group G
Haemophilus influenzae
Staphylococcus aureus
Streptococcus mitis group
Streptococcus pneumoniae

1 gtt into affected eye (s) BID (8-12 hrs apart for first 2 days), then 1 gtt once daily for 5 days
What is Voltaren Ophthalmic Solution?
Voltaren (Diclofenac) 0.1% Solution

MOA: NSAID- inhibits COX , decrease inflammation

Use: Treatment of postoperative inflammation following cataract extraction

Some burning and stinging upon instillation
What is Nevanac?
Nevanac (Nepafenac) 0.1% ophthalmic suspension

MOA: prodrug structure of nepafenac- allows for rapid penetration to the cornea and distribution to target sites- potent COX 1 and COX 2 inhibitor

NSAID- inhibits COX, decreases inflammation

Use: pain and inflammation associated with cataract surgery

1gtt into affected eye TID beginning 1 day prior to cataract surgery, continue on day of surgery, and for 2 weeks after
What is Acular?
Acular (Ketorolac) 0.5% soln

NSAID- inhibits COX, decreases inflammation

Use:

1. relief of ocular itching caused by seasonal allergic conjunctivitis

2.treatment of post op inflammation for cataract extraction

1 gtt QID beginning 24 hr after surgery... continue thru 2 weeks of post-op period
What is Acular LS?
Acular LS (Ketorolac) 0.5% soln.

NSAID- inhibits COX, decreases inflammation

Use: reduction of ocular pain and burning/stinging for up to 4 days time/day beginning 24 hrs after cataract surgery and continuing through the first 2 weeks of the post-op period

1gtt QID PRN for pain and burning/stinging for up to 4 days
What is Patanol?
Patanol (Olopatadine HCl) 0.1% solution BID
Pataday (Olopatadine HCl) 0.2% solution QD

MOA: inhibits histamine release from mast cells and blocks H-1 receptors

Use: Itchy eyes due to allergic conjunctivitis
What is Restasis?
Restasis (Cyclosporine) 0.05%

Use: increase tear production

MOA: immunosuppressive agent; partial immunomodulator