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4 Cards in this Set
- Front
- Back
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Adefovir
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NRTI (A analog)
Tx: DNA/RNA viruses, HBV Prodrug MoA: Inhib's viral DNA poly Chain termination AE: nephrotoxicity |
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Interferon alpha (2b)
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Recombinant antiviral protein
Tx: HBV, HCV Induced by viral ds RNA Interferon stimulated genes (ISG's) are expressed Coadmin with ribavirin |
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Ribavirin
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NRTI? (G analog)
Tx: RNA/DNA viruses: HCV (1st line), respiratory syncytial virus in kids, influenza MoA: monophosphate: inhib's guanine synthesis (inhib's inosine monophosphate dehydrogenase) triphosphate: incorporated into RNA causing chain termination, and weakly inhib's viral RNA poly |
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Lamivudine
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NRTI (C analog)
Tx: HBV (low dose), HIV (higher dose) MoA: inhib's reverse transcriptase enzyme in HBV and HIV, and causes chain termination |
