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9 Cards in this Set
- Front
- Back
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Solutes reabsorbed in proximal tubule?
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Na, Cl, HCO3(bicarbonate)
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Proximal tubule:
basolateral transporters? luminal transporters? channels? |
baso: Na/K exchanger, HCO3 transporter
luminal: Na/H exchanger, Cl/base exchanger channels: none Carbonic anhydrase inside cell and in luminal membrane |
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Solutes reabsorbed in ascending LoH?
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Na, Cl, Mg, Ca, and K
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Ascending LoH:
basolateral transporters? luminal transporters? channels? |
baso: Na/K exchanger, K/Cl symporter
luminal: Na/K/Cl symporter, K channel (out) Mg and Ca paracellular (in) |
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Solutes reabsorbed in Distal Convoluted Tubule?
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Na, Cl, Ca
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Distal Convoluted Tubule:
basolateral transporters? luminal transporters? channels? |
baso: Na/K exchanger, Ca/Na exchanger, Ca/H exchanger, Cl channel(into blood), K channel(into blood, not shown)
luminal: Na/Cl symporter, Ca channel(in) |
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Solutes reabsorbed in Collecting Tubules and Ducts?
Solutes lost? |
Na, Cl, HCO3
H(intercalated), K(principal) lost. |
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Collecting Tubules and Ducts:
basolateral transporters? luminal transporters? channels? |
Principal cells:
baso: Na/K exchanger luminal: Na channel(in), K channel(out) Intercalated cells: baso: HCO3/Cl exchanger luminal: H pump(out) |
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What diuretics operate in each section of the nephron tubule?
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Proximal: Carbonic Anhydrase inhibitors
Asc LoH: Loop diuretics on Na/K/Cl symporter Distal convoluted tubule: Aldosterone inhibitors on Na/Cl symporter, Thiazide diuretics also on Na/Cl symporter, and on CA(minor) Collecting tubules and ducts: Aldosterone inhibitors on principal cells on luminal Na channel(in) and on basolateral Na/K exchanger |
