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88 Cards in this Set

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cefazolin (1)
cephalosporins : surgical prophylaxis (DOC); skin & soft tissue infections (staph. Aureus & Strep)
cefoxitin (2)
cephalosporins : intra-abdominal surgery prophylaxis (anaerobes)
cefotetan (2)
cephalosporins : intra-abdominal surgery prophylaxis (anaerobes)
cefotaxime (3)
cephalosporins : strep pneumoniae infxns (or B-Hemolytic Strep)
ceftriaxone (3)
cephalosporins : strep pneumoniae infxns (or B-Hemolytic Strep)
ceftazidime (3)
cephalosporins : Pseudomonas aeruginosa
cefepime (4)
cephalosporins : critically ill pts; pseudomonas; gram negative meningitis
penicilin G (i.v.)
penicillins: B-hemolytic strep (includes Grp A Strep); susceptible S. pneumoniae infxns; meningococcal meningitis (pcn G is DOC for all) ***(most S. aureus is resistant)
penicillin VK (p.o)
penicillins: B-hemolytic strep (includes Grp A Strep); susceptible S. pneumoniae infxns; meningococcal meningitis (pcn G is DOC for all) ***(most S. aureus is resistant)
procaine pcn G
penicillins: B-hemolytic strep (includes Grp A Strep); susceptible S. pneumoniae infxns; meningococcal meningitis (pcn G is DOC for all) ***(most S. aureus is resistant)
benzathine pcn G
penicillins: B-hemolytic strep (includes Grp A Strep); susceptible S. pneumoniae infxns; meningococcal meningitis (pcn G is DOC for all) ***(most S. aureus is resistant)
oxacillin (i.v.)
penicillins: soft tissue cellulitis (non-MRSA) (DOC); always better than vanc
nafcillin (i.v.)
penicillins: soft tissue cellulitis (non-MRSA) (DOC); always better than vanc
dicloxacillin (p.o.)
penicillins: soft tissue cellulitis (non-MRSA)
cloxacillin (p.o.)
penicillins: soft tissue cellulitis (non-MRSA)
ampicillin (i.v.)
penicillins: 1st line for otitis media (DOC); some gram negs too (add clav for 3rd AOM)
amoxacillin (p.o)
penicillins: 2nd line for otitis media (DOC); some gram negs too (add clav for 3rd AOM)
piperacillin
penicillins: pseudomonas; systemic gram negatives (kleb.; proteus; serratia)
ticarcillin
penicillins: pseudomonas; systemic gram negatives (kleb.; proteus; serratia)
clavulanate
β-lactamase Inhibitors: give w/ piperacillin (ICU); ticarcillin (ICU); amoxicillin & ampicillin
sulbactam
: give w/ piperacillin (ICU); ticarcillin (ICU); amoxicillin & ampicillin
tazobactam
: give w/ piperacillin (ICU); ticarcillin (ICU); amoxicillin & ampicillin
imipenem/cilastatin
cabapems & monobactams: very broad spectrum: MultiDrug Resistant (MDR) pathogens; polymicrobial life-threatening infxn. (i.e. massive contamxns - GI explosion); Febrile neutropenics (for cancer & immunocompromised Pts)
meropenem
cabapems & monobactams: very broad spectrum: MultiDrug Resistant (MDR) pathogens; polymicrobial life-threatening infxn. (i.e. massive contamxns - GI explosion); Febrile neutropenics (for cancer & immunocompromised Pts)
ertapenem
cabapems & monobactams: very broad spectrum: MultiDrug Resistant (MDR) pathogens; polymicrobial life-threatening infxn. (i.e. massive contamxns - GI explosion); Febrile neutropenics (for cancer & immunocompromised Pts)
aztreonam (i.v.)
cabapems & monobactams: aerobic gram -s (pseudomonas)
amikacin
amino-glycosides (Has post Ab-effect - works against bacteria even after drug gone): aerobic G - bacilli (GIVE HIGH DOSES) (but resistance readily develops b/c of bact. enz. activation- less w/ amik); G + : give w/ β-lactam; ceph or vanc for synergistic killing (GIVE LOW DOSES)
gentamicin
amino-glycosides (Has post Ab-effect - works against bacteria even after drug gone): aerobic G - bacilli (GIVE HIGH DOSES) (but resistance readily develops b/c of bact. enz. activation- less w/ amik); G + : give w/ β-lactam; ceph or vanc for synergistic killing (GIVE LOW DOSES)
tobramycin
amino-glycosides (Has post Ab-effect - works against bacteria even after drug gone): aerobic G - bacilli (GIVE HIGH DOSES) (but resistance readily develops b/c of bact. enz. activation- less w/ amik); G + : give w/ β-lactam; ceph or vanc for synergistic killing (GIVE LOW DOSES)
ciprofloxacin
fluoroquinolines: gram + activity (not MRSA or VRE) (M>G>L>C); ~ 40% of pseudomonas (C=L>G>M); anaerobics (M=G>L=C); intracellular pathogens & other gram - (except pseudomonas); DOC for inpatient CAP & complicated UTIs (only for susceptible E. coli; D82 increasing); MDR S. pneumo; systemic salmonella
levofloxacin
fluoroquinolines: gram + activity (not MRSA or VRE) (M>G>L>C); ~ 40% of pseudomonas (C=L>G>M); anaerobics (M=G>L=C); intracellular pathogens & other gram - (except pseudomonas); DOC for inpatient CAP & complicated UTIs (only for susceptible E. coli; ®increasing); MDR S. pneumo; systemic salmonella
gatifloxacin
fluoroquinolines: gram + activity (not MRSA or VRE) (M>G>L>C); ~ 40% of pseudomonas (C=L>G>M); anaerobics (M=G>L=C); intracellular pathogens & other gram - (except pseudomonas); DOC for inpatient CAP & complicated UTIs (only for susceptible E. coli; ®increasing); MDR S. pneumo; systemic salmonella
gemiflozacin
fluoroquinolines: gram + activity (not MRSA or VRE) (M>G>L>C); ~ 40% of pseudomonas (C=L>G>M); anaerobics (M=G>L=C); intracellular pathogens & other gram - (except pseudomonas); DOC for inpatient CAP & complicated UTIs (only for susceptible E. coli; ®increasing); MDR S. pneumo; systemic salmonella
moxifloxacin
fluoroquinolines: gram + activity (not MRSA or VRE) (M>G>L>C); ~ 40% of pseudomonas (C=L>G>M); anaerobics (M=G>L=C); intracellular pathogens & other gram - (except pseudomonas); DOC for inpatient CAP & complicated UTIs (only for susceptible E. coli; ®+D23increasing); MDR S. pneumo; systemic salmonella
azithromycin
macrolides: good gram + (NO MRSA or VRE or enterococcus); out-Pt. mgmt of CAP (DOC); Legionella; M. avium; Chlamydia; Mycoplasma pneumoniae (CAP: Community Acquired Pneumonia - Typical & Atypicals)
erythromycin
macrolides: good gram + (NO MRSA or VRE or enterococcus); out-Pt. mgmt of CAP (DOC); Legionella; M. avium; Chlamydia; Mycoplasma pneumoniae (CAP: Community Acquired Pneumonia - Typical & Atypicals)
clarithromycin (p.o)
macrolides: good gram + (NO MRSA or VRE or enterococcus); out-Pt. mgmt of CAP (DOC); Legionella; M. avium; Chlamydia; Mycoplasma pneumoniae (CAP: Community Acquired Pneumonia - Typical & Atypicals)
clindamycin
other antibiotics: excellent gram + coverage (staph & strep); soft tissue infxns; no gram - & little MSRA activity; good for pulm. anaerobes; Decrease B. fragilis suscept. (NO VRE); Plasmodium
vancomycin (i.v.)
other antibiotics: MRSA (DOC); gram + organisms only; amp-resistant enterococcus; meningitis; MDR S. pneumonia infxn; 2nd line tx of pseudomemb. Colitis (C. deficile); Febrile neutropenics
quinupristin/dalfopristin
other antibiotics: ( - cidal: strep; most staph); (** MRSA); ( - static: Enterococcus faecium (*** VRE)); MDR gram + (great G+ coverage!)
linezolid
other antibiotics: Enterococcus faceium AND faecalis; ( -static: VRE infections (DOC) & select MRSA); MDR G+ (min. G - activity)
trim-sulfa
other antibiotics: Broad spectrum: S. aureus; Enterobacter; E. coli; Klebsiella; UTIs; pneumocystis carinii pneumonia in AIDS patients (DOC); toxoplasmosis (may help w/ MRSA in future)
nitrofurantoin
drugs that treat UTIs (another Antibiotic): UTIs (not pseudomonas)
Tetracycline HCl
tetracyclines: rickettsial infxns (RMSF - DOC); Lyme Disease (B. burgdorferi) DOC; **mycoplasma pneumoniae (CAP); chlamydia; acne; moderate gram + and gram - activity; Plasmodium
doxycycline
tetracyclines: rickettsial infxns (RMSF - DOC); Lyme Disease (B. burgdorferi) DOC; **mycoplasma pneumoniae (CAP); chlamydia; acne; moderate gram + and gram - activity; Plasmodium
minocycline
tetracyclines: used esp. for **acne
niclosamide
antihelmintic drugs: tapeworm/Cestodes (DOC) (cant get in USA)
praziquantel
antihelmintic drugs: schistosomiasis (DOC) (Flukes/Tremetodes)
mebendazole
antihelmintic drugs: Broad Coverage: roundworms tapeworms; pinworms; whipworms; hookworms
albendazole
antihelmintic drugs: mixed infections; roundworms; pinworms; whipworms; hookworms; ***cysticercosis (DOC for all these)
pyrantel pamoate
antihelmintic drugs: pinworms
ivermectin
antihelmintic drugs: threadworm
chloroquine
antimalarial drugs: use together for malaria treatment (need both for total cure); but chloroquine is DOC
primaquine
antimalarial drugs: use together for malaria treatment (need both for total cure); but chloroquine is DOC
antimalarial drugs: Toxoplasma (DOC)
mefloquine
antimalarial drugs: MDR P. falicparum; DOC in Africa (lots of CQ resist.)
PERMETRIN
ECTOPARASITE DRUGS: MDR P. falicparum; DOC in Africa (lots of CQ resist.)
metronidazole
antiprotozoal drugs: amebiasis; trichomoniasis; some anaerobic coverage (bacteriocidal); pseudomembranous colitis (DOC); B. fragilis (abd. Cavity probs); C. difficile; giardiasis (from contam. H2O; daycare)
Griseofulvin
antifungal drugs: dermatophytes: tinea corporis (ringworm); tineal capitas (scalp ringworm); tinea cruris (jock itch); tenia pedis (athletes foot)
Miconazole
antifungal drugs: candida vulvovaginitis
Clotrimazole
antifungal drugs: candida vulvovaginitis
Itraconazole
antifungal drugs: Aspergillus infxns
Fluconazole (p.o.)
antifungal drugs: systemic Candidia albicans infxns (but takes 48 hrs b/4 effects take place - so; not really recommened)
terbinafine (p.o.)
antifungal drugs: fungal nail infections - Onychomycosis (DOC); athletes foot & jock itch
nystatin
antifungal drugs: susceptible cutaneous; mucocutaneous & oral fungal infectxns (candidia -- i.e. thrush) (w/ swish & swallow)
amphotericin B
antifungal drugs: i.v. for resistant oral candidiasis or severe systemic infections (cryptococcus; aspergillus; neisseria)
Rimantadine
Anti-viral: for Influenza
Vidarabine
anti-herpes drugs: herpes simplex keratitis
acyclovir
anti-herpes drugs: herpesviruses (not effective against latency - cant eradicate infxn; only infected cells affected) (Bells Palsy); prophylaxis for CMV retinitis for Pts w/ transplanted organs
valacyclovir
anti-herpes drugs: herpesviruses (not effective against latency - cant eradicate infxn; only infected cells affected) (Bells Palsy); prophylaxis for CMV retinitis for Pts w/ transplanted organs
foscarnet
anti-CMV drugs: CMV infection (CMV retinitis) (Acyclovir & Valacyclovir uses as prophylaxis for CMV)
cidofovir
anti-CMV drugs: CMV infection (CMV retinitis) (Acyclovir & Valacyclovir uses as prophylaxis for CMV)
fomivirisen
anti-CMV drugs: CMV infection (CMV retinitis) (Acyclovir & Valacyclovir uses as prophylaxis for CMV)
Slavudine
NRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
Abacavir
NRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
Lamivudine
NRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
Tenofovir
NRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
zidovudine
NRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
saquinavir
HIV protease inhibitors: HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
ritonavir
HIV protease inhibitors: HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
lopinavir
HIV protease inhibitors: HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
nivirapine
NNRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
efavirenz
NNRTI (anti-HIV): HIV infection (use in combination - additive effect) 1) 2 NRTI + 1 NNRTI 2) 2 NRTI + 1 PI 3) 3 NRTIs
pyrazinamide (PZA)
anti-TB drugs: treatment of TB (need 4 drugs) ("RIPE")
ethambutol
anti-TB drugs: treatment of TB (need 4 drugs) ("RIPE")
rifampin
anti-TB drugs: treatment of TB (need 4 drugs) ("RIPE")
isoniazid (INH)
anti-TB drugs: treatment of TB (need 4 drugs) ("RIPE")
streptomycin
anti-TB drugs: first agent used for TB