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59 Cards in this Set

  • Front
  • Back
What are the 5 axes of the DSM-IV-TR?
I - primary psych diagnosis
II - personality and developmental disorders
III - physical or general medical disorder
IV - psychological stressors
V - global assesment of functioning (GAF)
What does a GAF score of 61-70 represent?
Mild sx

Serious sx

Danger of hurting self or others
Components of the AMSIT Mental Status Exam?
Appearance, behavior & speech
Mood and affect
Level of Intellectual functioning
Thought process
Rating scale for schizophrenia?
Brief Psychiatric Rating Scale (BPRS)
Rating scale for mood disorders?
Beck Depression Inventory (BDI), Hamiltion Depression Rating Scale (HAMD)
Rating scale for anxiety?
Hamiltion Anxiety Rating Scale (HAMA)
Rating scale for dementia?
Rating scale for OCD?
Yale-Brown Obsessive Compulsive Scale (YBOCS)
Rating scale for tardive dyskinesia?
Abnormal Involuntary Movement Scale (AIMS)
Fx of cerebrum's frontal lobe?
personality, memory, reasoning, concentration...Alzheimer's, depression, mania
Fx of cerebrum's parietal lobe?
Sensory processing...Alzheimer's
Fx of cerebrum's occiptal lobe?
visual recognition
Fx of cerebrum's temporal lobe?
speech, written/verbal/visual cueing...Alzheimer's, depression, mania
Disease associated with cerebral cortex?
Disease associated with basal ganglia?
Disease associated with limbic system?
Where do ACh tracts begin?
cell bodies at base of frontal lobe
Enzymes that break down ACh?
acetylcholinesterase & butyrlcholinesterase
Where do NE tracts begin?
locus coeruleus
Enzyme that breaks down NE?
Location of ALPHA 1 receptors?
brain, heart, smooth muscle
Effects of ALPHA 1 agonism?
increased NE, increased BP, vasoconstriction, orgasm, tachycardia
Examples of ALPHA 1 agonist?
NE, epi, phenylepherine, Sudafed
Effects of ALPHA 1 antagonism?
decreased NE, decreased BP with reflex tachycardia
Examples of ALPHA 1 antagonists?
prazosin, TCAs, chlorpromazine
Location of ALPHA 2 receptors?
brain, pancreas, smooth muscle
Effects of ALPHA 2 agonism?
inhibits NE release, decreased BP
Example of ALPHA 2 agonist?
Effects of ALPHA 2 antagonists?
block autoreceptors and increase NE
Example of ALPHA 2 antagonist?
Location of BETA 1 receptors?
heart, brain
Effects of BETA 1 agonism?
increased HR
Examples of BETA 1 agonists?
epi, dobutamine, isoproterenol
Location of BETA 2 receptors?
lungs, brain, skeletal muscle
Effects of BETA 2 agonism?
bronchodilation, uterine muscle contraction, increased blood sugar, vasodilation
Effects of BETA 1 and 2 antagonists?
decreased BP and HR, peripheral vasoconstriction
Example of BETA antagonists?
Effects of H1 receptors in hypothalamus?
inhibit appetite, increase wakefulness, motion sickness, vertigo
Anxiety and depression related to what histamine receptor family?
Migraine related to what histamine receptor family?
Hallucinations related to what histamine receptor family?
Appetite related to what histamine receptor family?
Peristalsis related to what histamine receptor family?
Where do serotonin tracts begin?
raphe nuclei cell bodies
Serotonin involved in?
emotions, cognition, sleep, appetite, sexual behavior, CV, cranial vessels
Sx of serotonin deficiency?
depression, obsession, compulsion, anxiety, panic, phobias, food cravings, aggression
Sx of serotonin excess?
anxiety, insomnia, GI disturbances, cardiac valve dysfunction
Sx of serotonin syndrome?
fever, tremor, coma, seizures, death
Sx associated with decreased dopamine?
parkinson's, decreased attention, hypersomnia, cravings, anhedonia, psuedodementia
Sx associated with dopamine overactivity?
pyschosis, schizophrenia
4 Tracts of Dopamine and their Fx
Nigrostriatal: movement
Tuberinfundibular: prolactin release
Mesolimbic: memory, emotion
Mesocortical: emotion, social function
Effects of GABA-a stimulation?
Cl influx, hyperpolarization, decreased cell excitability
Defect with decreased ACh?
Defect with increased Dopamine?
Defect with decreased Dopamine?
Parkinson's, substance abuse
Defect with decreased NE?
Defect with decreased serotonin?
depression, OCD
Defect with decreased GABA?
Defect with increased Glutamate?
bipolar, psychosis from neurotoxicity