Oxidative Phosphorylation Flashcards

Front 1

In the mitochondria, this membrane protein uses a proton gradient to generate ATP.

Back 1

ATP synthase

Front 2

Electron transport complexes I-IV , and ATP synthase are found here.

Back 2

inner mitochondrial membrane

Front 3

Complex I - NADH:ubiquinone oxidoreductase

Back 3

- 2 electrons enter via 1 NADH
- FMN --> FMNH2
- Q --> QH2, receives protons via FMNH2
- 4 H+ are translocated

Front 4

Complex II - succinate:ubiquinone oxidoreductase

Back 4

- accepts electrons from succinate to reduce Q --> QH2

Front 5

Complex III - ubiquinol:cytochrome C oxidoreductase

Back 5

- QH2 is oxidized and recycled
- two cyt c are reduced with one electron each
- 4 H+ are translocated

Front 6

Complex IV- cytochrome c oxidase

Back 6

- contains a subunit with copper
- 4 cyt c are oxidized to reduce 1 oxygen molecule and produce 2 water molecules.

Front 7

Complex V - ATP synthase

Back 7

- has a knob and stalk structure
- F1 contains the catalytic subunits
- Fo (stalk) has a proton channel
- rotational motion is coupled with proton movement which drives production of ATP

Front 8

the P:O ratio

Back 8

ADP phosphorylated/atoms of oxygen reduced

- translocation of 3H+ for each ATP produced
- 1H+ needed for transport of Pi, ADP, and ATP

Front 9

NADH P:O ratio

Back 9

2.5 ATP/O

Front 10

Succinate P:O ratio

Back 10

1.5 ATP/O