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75 Cards in this Set

  • Front
  • Back

Hypogastric mass

Ovarian cancer usually presents as

50s and 60s

Ovarian cance ris common in

GIT and GUT

In a patient who presents with hypogastric or adnexal mass, etiology may arise from

Urinoma

retention of urine that may present as a mass

Benign

cystic, movable, non-tender, no ascites, unilateral

Malignant

solid, fixed, nodular, associated with ascites, bilateral

Incessant ovulation

repeated trauma of the surface epitheium of the ovary in a patient who is always ovulating

Nulligravid

always ovulating, increased risk

Pregnancy

no ovulation for 9 months, decreased risk

Use of OCPs

inhibits ovulation, decreased risk

Stage 1A

single ovary or single fallopian tube, regardless of size

Stage1B

both ovaries, or both fallopian tubes, regardless of size

Stage IC1

intraoperative rupture or spillage

Stage IC2

preoperative rupture

Stage IC3

presence of malignant cells in the peritoneal fluid or ascites on peritoneal fluid cytology

Stage IIA

ovary affects the uterus and/or fallopian tube, or the fallopian tube affects the uterus and/or the ovary

Stage II

Primary peritoneal carcinoma is regarded as

Stage IIB

ovary or fallopian tube affects other pelvic organs such as the bladder and the rectal serosa

Stage IIIA1

positive lymph node involvement

Stage IIIA2

histologic evidence of malignancy, with normal looking omentum

Stage IIIB

there is mass on the omentum measuring less than or equal to 2 cm

Stage IIIC

there is mass on the omentum measuring more than 2 cm

Stage IVA

involves the chest & lungs

Stage IVB

presence of hepatic parenchyma involvement

Epithelial Stomal Tumors

They are believed to arise from the surface epithelium

Serous Tumor

poor prognosis becuase it is usually high grade

Serous Tumor

cells resemble that of fallopian tube (cuboidal cells)

Serous Tumor

Psammoma bodies

Mucinous Tumor

mass is usually big, enough to greatly distend the abdomen

Mucinous Tumor

Secrete mucin, cells resembles the endocervix ad the GI

Mucinous Tumor

If frozen section diagnosed, do additional appendectomy

Psedomyxoma peritonei

transformation of peritoneal mesothelium to a mucin secreting epithelium

Endometrioid Tumor

consist of epithelial cells resembling those of the endometrium

Clear Cell Tumor

cells resemble that of the endometrium

Clear Cell Tumor

contains hobnail cells, which secrete glycogen

Clear Cell Tumor

molecular evaluation suggests a homology to similar pathology in kidney

Brenner Tumor

cells resemble that transitional cells of the bladder

Brenner Tumor

A solid tumor that may be benign with abundant stroma

Brenner Tumor

Epithelioid cells show "coffee bean" pattern caused by longitudinal grooving of nuclei

Brenner Tumor

These tumors are derived from the germ cells of the ovary

Germ Cell Tumor

composed of extraembryonic elements or may have features that resemble any or all three embryonic layers

Mature Cystic Teratoma

Most common benign ovarian lesion among women

Mature Cystic Teratoma

Contains 3 germ cell layers: teeth, subcutaneous glands, hair

Mature Cystic Teratoma

Commonly floats, and causes torsion of ovary

Struma Ovarii

Same appearance with that of the thyroid follicle

Carcinoid Tumor

Commonly seen in patients with Turnerrrrr's Syyndrome, or gonadal dysgenesis

Dysgerminoma

Most common malignant germ cell tumor

Dysgerminoma

Analogous to the male seminoma

Dysgerminoma

secretes B-hCG

Dysgerminoma

consist of primitive germ cellss with stromaa infiltrated by lymphocytes

Yolk Sac Tumor

2nd most common germ cell tumor

Yolk Sac Tumor

Schiller-Duval Bodies

Yolk Sac Tumor

tumor secretes a-fetoprotein

Immature Teratoma

3rd most common germ cell tumor

Immature Teratoma

neuroepithelium

Embryonal Carcinoma

commonly observed in sexual precocity

Embryonal Carcinoma

secretes B-hCG and a-fetoprotein

Embryonal Carcinoma

Trophoblastic elements may be present

Choriocarcinoma

gives false-positive pregnancy test

Choriocarcinoma

consists of malignant cytotrophoblasts and syncytiotrophoblast

Sex Cord Stromal Tumor

derived from the sex cords of the ovary and the specialized stroma of the developing gonad

Sex Cord Stromal Tumor

elements can have male and female differentiation and some are hormonally active

Fibroma

part of Meig's syndrome

Meig's syndrome

Triad: pleural effusion, ascites, fibroma

Fibroma

most common benign solid ovarian tumor, does not secrete hormones

Fibroma

Benign, and excision is adequate treatment

Fibroma

can be responsible for hydrothorax with a benign ascites

Thecoma

benign tumor that consists entirely of stroma cells

Thecoma

associated with estrogen production but ot as frequently as granulosa cell tumors

Granulosa-Theca Cell Tumor

Cal-Exner Bodies

Cal-Exner Bodies

rosette formation of granulosa cells

Granulosa-Theca Cell Tumor

secretes inhibin and anti-Mullerian hormone

Granulosa-Theca Cell Tumor

In postmenopausal women, can produce increased levels of lood estrogens, uterine bleeding, and ocassionally endometrial carcinoma

Sertoli-Leydig Cell Tumor

occur in young women of reproductive age and frequently are the cause of masculinization and hirsutism

Testosterone

tumor marker for Sertoli-Leydig Cell Tumor