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8 Cards in this Set
- Front
- Back
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Class of acetaminophen
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Analgesic, Antipyretic
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Acetaminophen brands
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APAP, Tylenol, Paracetamol
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Acetaminophen MOA --> analgesic
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inhibit synthesis of prostaglandins in CNS (via COX-1&2 inhibition) and peripherally blocks pain impulse generation
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Acetaminophen MOA --> antipyretic
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Direct inhibitory action of endogenous pyrogen on hypothalamic heat-regulating which increases heat dissipation via sweating and vasodilation
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Acetaminophen Indications
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analgesia, antipyretic
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Acetaminophen dosing for children (>12) and MDD
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10-15 mg/kg/dose q 4-6h prn
MDD 2600mg |
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Acetaminophen dosing for adults and MDD
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325-600mg q 4-6h prn
650-1000mg q 4-6h prn MDD 4000mg/day |
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Acetaminophen Warnings/Contraindications
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Alcohol intake, hepatic dysfuntion, warfarin
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