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13 Cards in this Set
- Front
- Back
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Paget's disease is characterized by increases in which enzyme?
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alkaline phosphatase
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_________ and ________ are the first line agents in management of Paget's disease.
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Biphosphonates...Fosamax (alendronate)
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What is the resulting mechanism of action of Biphosphonates?
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suppress bone resorption by osteoclasts
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Which drug can be given IV in the management of Paget's disease if fosamax is not tolerated?
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Pamidronate
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What is the drug of choice for Paget's with extensive lytic disease?
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calcitonin
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_______ is the drug of choice prior to elective surgery in patients with Paget's disease.
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Calcitonin
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What are the drugs used to manage Paget's disease?
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BIPHOSPHONATES
FOSAMAX Pamidronate Etidronate Calcitonin Salmon Calcitonin |
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What are the disease characteristics of Osteoporosis?
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Low bone mass
Structural deterioration of bone tissue |
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What are some risk factors for the development of Osteoporosis?
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Being female
Advanced age Post-menopause Amenorrhea Malnutrition Use of corticosteroids and anti-convulsants Low testosterone (in men) Smoking/Drinking |
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What are some examples of medications that cause bone loss?
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Glucocorticoids
Anti-seizure meds GnRH analogs Aluminum-containing antacids Some cancer treatments Excessive thyroid hormone |
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In order to prevent osteoporosis, it is recommended that calcium intake _________ during pregnancy and nursing and with advanced age.
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increase
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What are the drugs used to prevent/treat osteoporosis?
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Estrogen
Fosamax (Alendronate) Calcitonin Raloxifene Risedronate |
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What medications can be used to treat/prevent glucocorticoid-induced osteoporosis?
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Risedronate
Fosamax (Alendronate) |
