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20 Cards in this Set
- Front
- Back
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What is Osteopenia?
|
t score 1- 2.5 SD below normal BMD measures.
Osteoporosis >2.5 SD below Normal BMD |
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Odds of developing Osteoporosis in
The USA |
males = 10 %
females= 40 % |
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Incidence of Osteoporosis,
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28 million Americans have Osteoporosis
By age 50 = 40 % of females will have fractures( wrist /hip/spine) By age 70= 90% of females will have hip fractures |
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Triad of Bone health
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Good Bone health=
Independant living = Longevity = |
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Facts and figures of Osteoporosis
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1.5 million people will have fractures related to Osteoporosis
700 ,000 will have vertebral fx each year 250,000 will have wrist fx Hip fx hospitalisations 300.000 each year cost of treatment of fx 18 billion = 38 million per day |
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Bone Density facts
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peak bone density in health is achieved around 25-35 years of age.
men have greater BMD than woman black woman have greater BMD than white stronger the BMD in the early years longer the density lasts to keep |
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Bone density facts
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Bone mass decreases by 1-5% each year in a woman greater than 40 y/o age
Bone mass decreases < 1% each year for men |
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Bone Histology/cell at work
|
Osteoblasts( osteogenesis)
osteoclasts (demineralise, resorption) osteocytes ( maintain the bone balance) |
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Bone Histo- pathophysiology
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Bone tissues are in a constant state of remodelling
Old bone is broken down and replaced by new bone. Osteoporosis occurs when you loose more than you REBUILD |
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Bone Histo-pathophysiology
|
Osteoblasts (make collagen, hydroxyapatite)
Osteoclasts demineralise by by dissolving the mineral matrix makes enzyme collagenase that break collagen that dissove hydroxyapatite |
|
|
What is Osteopenia?
|
t score 1- 2.5 SD below normal BMD measures.
Osteoporosis >2.5 SD below Normal BMD |
|
|
Odds of developing Osteoporosis in
The USA |
males = 10 %
females= 40 % |
|
|
Incidence of Osteoporosis,
|
28 million Americans have Osteoporosis
By age 50 = 40 % of females will have fractures( wrist /hip/spine) By age 70= 90% of females will have hip fractures |
|
|
Triad of Bone health
|
Good Bone health=
Independant living = Longevity = |
|
|
Facts and figures of Osteoporosis
|
1.5 million people will have fractures related to Osteoporosis
700 ,000 will have vertebral fx each year 250,000 will have wrist fx Hip fx hospitalisations 300.000 each year cost of treatment of fx 18 billion = 38 million per day |
|
|
Bone Density facts
|
peak bone density in health is achieved around 25-35 years of age.
men have greater BMD than woman black woman have greater BMD than white stronger the BMD in the early years longer the density lasts to keep |
|
|
Bone density facts
|
Bone mass decreases by 1-5% each year in a woman greater than 40 y/o age
Bone mass decreases < 1% each year for men |
|
|
Bone Histology/cell at work
|
Osteoblasts( osteogenesis)
osteoclasts (demineralise, resorption) osteocytes ( maintain the bone balance) |
|
|
Bone Histo- pathophysiology
|
Bone tissues are in a constant state of remodelling
Old bone is broken down and replaced by new bone. Osteoporosis occurs when you loose more than you REBUILD |
|
|
Bone Histo-pathophysiology
|
Osteoblasts (make collagen, hydroxyapatite)
Osteoclasts demineralise by by dissolving the mineral matrix makes enzyme collagenase that break collagen that dissove hydroxyapatite |
