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17 Cards in this Set
- Front
- Back
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Most common Clades of HIV in the Phils |
Clades B and E |
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Three major gene regions in HIV and their functions |
Pol a replication gag - capsid proteins env - envelope |
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Produces a regulatory protein that speeds up transcription of the HIV provirus. |
tat gene |
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rev gene |
Encodes for a regulatory protein which switches the processing of viral RNA transcripts to a pattern that predominates with established infection, leading to production of viral structural and enzymatic proteins.e |
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CCR5 |
Most common cofactor required for the entry of virus |
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Cells that express CD4 |
T cells mononuclear phagocyte system B cells NK Cells Dendritic cells Stem cells GI epithelial cells Microglia galactosylceramide receptors in brain and bowel |
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Found in the anus |
T-tropic |
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Found in vagina |
M-tropic strain |
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RNA dependent DNA polymerase |
Reverse transcriptase |
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Found in the anus |
T-tropic |
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Found in vagina |
M-tropic strain |
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RNA dependent DNA polymerase |
Reverse transcriptase |
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Helps facilitate integration of viral dna into host |
Integrase |
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Last enzyme used by HIV |
Protease |
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HIV 1 is closer to |
Chimpanzees |
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HIV 2 is closer to |
Macaques and Managabeys |
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Modes of HIV Transmission |
Sexual, Parenteral, Perinatal |
