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4 Cards in this Set

  • Front
  • Back
Describe Orthomyxo
Negative sense, single stranded RNA with 8 genome segments, helical, enveloped, pleomorphic
What are the integral membrane proteins
HA, antireceptor, attaches to sialic acid
NA removes terminal sialic acid from cell surface
M1 Matrix protein
M2 ion channels
NS1
How doe sit enter the cell
receptor mediated endocytsis
What is the role of M2 Ion Channel
Virus in enndozome
Low pH activate ion channel allowing protons to enter virions. Polymerase expand allowing fusion between virus and endosome and releasing RNA