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4 Cards in this Set
- Front
- Back
Describe Orthomyxo
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Negative sense, single stranded RNA with 8 genome segments, helical, enveloped, pleomorphic
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What are the integral membrane proteins
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HA, antireceptor, attaches to sialic acid
NA removes terminal sialic acid from cell surface M1 Matrix protein M2 ion channels NS1 |
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How doe sit enter the cell
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receptor mediated endocytsis
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What is the role of M2 Ion Channel
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Virus in enndozome
Low pH activate ion channel allowing protons to enter virions. Polymerase expand allowing fusion between virus and endosome and releasing RNA |