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21 Cards in this Set
- Front
- Back
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How stable are orthomyoxoviruses?
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very fragile
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What is the only disease associated with orthoviruses?
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influenza virus
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T/F ortho viruses use surface fusion proteins?
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false
paramyxoviruses use fusion proteins, ortho is endocytosed into the cell |
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How are influenza viruses classified?
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by their hemagglutinin and neuroamidase
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Where do orthoviruses replicate?
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in the cytoplasm and the nucleus
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What is cap snatching?
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when a virus cleaves host mRNA and uses it as a primer for transcription with viral RNA polymerase
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Where do all influenza viruses of mammals come from?
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avian influenza
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Genetic reassortment causes what type of antigenic change?
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genetic shift
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What type of change do point mutations cause?
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genetic drift
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What host can avian and human influenza viruses replicate in?
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pigs
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What type of infection does the influenza virus cause in mammals and birds?
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Mammals have a localized infection in the respiratory tract with no viremia
Birds have systemic infections |
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What is the prevalent equine strain of influenza?
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miami (A/H3N8)
there is no carrier state |
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What does canine influenza mimic?
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Kennel cough
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What is the severity of swine influenza?
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secondary bacterial infections and ascaris suum
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What is the etiological agent of fowl plague?
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influenza virus A
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What is the difference in clincal signs of avian influenza and other species?
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There is nervous system involvement in birds birds are often cyanotic
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What is the most pathogenic strain of avian influenza?
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HPAI
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Who are mostly effected by avian influenza?
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turkeys more than chickens there is zoonotic potential
the reservoir hosts are migratory fowl |
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T/F there is abortion seen with equine influenza.
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true due to prolonged fever
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What is the canine influenza virus a mutation of?
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Equine influenza H3N8
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What is the most important strain of swine flu and who are the hosts?
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H1N1
swine, humans and turkeys |
