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14 Cards in this Set
- Front
- Back
Predisposing factors
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abx tx, steroid tx, very young/old, immunocompromise
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Resistant strains
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fluconazole-resistant C. albicans
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HIV stats
*relapse expected? |
50% with HIV
80-95% with AIDS (esophageal in 10-15%) *Yes |
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Bone transplant association %
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30-40%
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AIDS-defining sites
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esophagus, trachea, bronchi, or lungs
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AKAs:
Psuedomembranous Erythematous Leukoplakia Angular cheilitis |
thrush
atrophic hyperplastic angular cheilitis |
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PE:
Thrush Atrophic Leukoplakia Angular cheilitis |
White/creamy plaques on mucosa; bleed with removal
Smooth, red, atrophic patches White plaques that can't be wiped off Erythema, fissuring at corners of mouth |
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Distrubution:
Thrush Atrophic Leukoplakia |
Dorsum tongue, buccal mucosa, hard/soft palate, pharynx-->esophagus and trachobronchial tree
Hard/soft palate, buccal mucosa, dorsal tongue Buccal mucosa, tongue, hard palate |
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Invasive associations
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Prolonged neutropenia
Hematogenous dissemination to skin/visera Prolonged cathing |
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DDX:
Thrush |
Oral hairy leukoplakia, condyloma accuminata, geographic tongue, hairy tongue, lichen planus, bite irritation
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DDX:
Atrophic |
Lichen planus
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Topical tx
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Nystatin
Clotrimazole |
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Oral tx
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Fluconazole
Itrazonazole Ketokonazole |
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Fluconazole-resistant tx
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50% resistant to itraconazole
Ampho B if sever Liposomal preps Maintenance therapy |