Organs

Front 1

where are WBC's/leukocytes made

Back 1

bone marrow

Front 2

where are leukocytes found

Back 2

blood and lymph circulation

Front 3

where do they exert their function

Back 3

connective and lymphatic tissues

Front 4

What are the classes of granulocytes

Back 4

neutrophils, eosinophils, basophils

Front 5

what are the classes of agranulocytes

Back 5

monocytes lymphocytes

Front 6

describe the cytoplasmic granules of granulocytes

Back 6

specific granules, non specific granules(lysosomes)

Front 7

describe the cytoplasmic granules of agranulocytes

Back 7

non specific granules(lysosomes)

Front 8

describe the morphology of neutrophils

Back 8

multilobed nucleus, specific clear granules in cytoplasm

Front 9

explain the function and prevalance of neutrophils

Back 9

phagocytosis and 60-70 percent of total leukocytes

Front 10

describe the function and prevalance of eosinophils

Back 10

1-5% and destruction of parasitic worms

Front 11

describe the morphology of eosinophils

Back 11

bilobed nucleus, pink, red, orange granules

Front 12

name the eosinophilic specific granules

Back 12

peroxidase, histaminase, arylsulfatase, acid phosphatase

Front 13

describe the prevalance, morphology and function of basophils

Back 13

.5-1%, immune responses, dark staining granules with a segmented nucleus

Front 14

name the basophilic granules

Back 14

hydrolytic enzymes, heparin, histamine, chondroitin sulfate, EDF-A or eosinophilic chemotactic factor or anaphylaxis

Front 15

describe the morphology, prevalance and function of monocytes

Back 15

2-10 percent, kidney shaped nucleus with blue gray cytoplasm, phagocytosis (macrophages in tissues)

Front 16

describe the morphology, prevalance and function of lymphocytes

Back 16

20-40 percent of leukocytes, dark purple circular nucleus, B lymphocytes humoral immunity, T lyphocytes cell mediated immunity

Front 17

what are the primary lymphatic organs

Back 17

bone marrow and thymus

Front 18

what is the function of the bone marrow with regards to lymphocyte functions

Back 18

lymphocytes formed here and B cells become immunocompetent.

Front 19

what is the function of the thymus with regards to lymphocyte functions

Back 19

t cells become immunocompetent

Front 20

What are the secondary lymphatic organs

Back 20

lymph nodes, spleen, mucosa associated lymphoid tissue (MALT)

Front 21

What happens in the secondary lymphatic organs

Back 21

immunocompetent lymphocytes contact antigens

Front 22

Does the thymus have B cells

Back 22

no

Front 23

What are hassals corpuscles

Back 23

arrangements of apoptotic epithelial reticular cells and T cells

Front 24

what do epithelial reticular cells do

Back 24

line the capillaries of the thymus to prevent immature t cells from contacting foreign antigens

Front 25

what is a follicle

Back 25

dense arrangement of B lymphocytes

Front 26

what is the paracortex

Back 26

a localization of T lymphocytes

Front 27

describe a stimulated follicle

Back 27

b lymphocytes surrounding a germinal center of b lymphoblasts that have begun to differentiate. The outer ring is called the corona

Front 28

what is found in the medulla of the lymph node

Back 28

cords of cells and sinuses

Front 29

what is cords of cells

Back 29

a mix of b and t cells

Front 30

what are sinuses

Back 30

open capillaries, places for lymph to accumulate

Front 31

describe the flow of blood into and out of the lymph node

Back 31

afferent lymphatic vessels enter on the convex side, drain into subcapsular sinuses that drain into trabecular and medually sinuses. Efferent lymphatic vessels exit at the hilum of the lymph node

Front 32

what supports the framework of the lymph node

Back 32

fine reticular fibers (collagen type III)

Front 33

what is the function of the spleen

Back 33

filter blood borne antigens and destruction of aged RBC's

Front 34

What are the divisions of the spleen and describe its blood flow

Back 34

white and red pulp and white pulp to red pulp central arteries branch into penicillar arteries which give rish to sheathed capillaries. Blood drains from sheathed capillaries into cords of cells and or venous sinuses in the red pulp

Front 35

what branches into central arteries in white pulp

Back 35

splenic artery

Front 36

what are PALS

Back 36

peri arteriolar lymphatic sheaths. Sheaths of t cells that surround the central artery

Front 37

what does the white pulp consist of

Back 37

a central artery surrounded by PALS with follicles of b cells embedded in them

Front 38

what is found in red pulp

Back 38

cords of cells and venous sinuses