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41 Cards in this Set
- Front
- Back
What is the flow of information through the Nervous system |
Stimulus -->Reception --> Transmission --> Integration --> CNS --> Transmission --> Response |
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What is the CNS |
CNS stands for Central Nervous System and is made up of the nerves in the spine and brain |
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What is the PNS |
PNS stands for Peripheral nervous system and this is comprised of all other nerves in the body |
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What are the types of Cells in the Nervous System? |
1. Neurons ~ Afferent or sensory ~ Efferent ~ Interneurons |
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What are electrical signals that are produced by neurons called? |
Nerve Impulses or Action potentials |
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What is the Cell body? |
Contains the nucleus, most of the cytoplasm, and most of the organelles |
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What are the two types of cytoplasmic processes and what do they do? |
1. Dendrites --> receive stimuli and conduct them towards the cell body 2. Axon --> conduct nerve impulses away from the cell body to another neuron or to a muscle or gland |
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What are Axon Collaterals? |
when an axon divides, it may form branches called axon collaterals |
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What are Synaptic Terminals? |
The branches that are formed at the end of an axon |
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What are Neurotransmitters? |
Synaptic terminals release them and they transmit signals from one neuron to another |
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What is a synapse? |
The junction between a synaptic terminal and another neuron |
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What are nodes of Ranvier? |
Gaps in the myelin sheaths (points in the axon not insulated with myelin) |
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What is an Axon Hillock? |
Conical region where the cell body connects to the axon. Site where synaptic inputs are summated before an action potential is transmitted to the axon. |
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What are axons surrounded by? |
special glial cells (Oligodendrocytes or Schwann cells) that form an insulating myelin sheath around the axon |
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What are bundles of axons called both in the PNS and the CNS? |
Nerves (PNS) Tracts (CNS) |
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What are Aggregations of nerve cell bodies called in both the CNS and PNS? |
Ganglia (PNS) Nuclei (CNS) |
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What are the four types of glial cells found in the vertebrate CNS? |
1. Astrocytes 2. Oligodendrocytes 3. Ependymal Cells 4. Microglia |
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What are Astrocytes |
1. Star-shaped glial cells that provide physical support for neurons 2. provide neurons with nutrients 3. Form tight junctions in the blood-brain barrier |
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What are Oligondendrocytes? |
Glial cells that form insulating myelin sheaths around neurons in the CNS ~ Speed transmission of neuron impulses |
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What are Ependymal cells? |
1. Ciliated glial cells that line internal cavities in the CNS 2. Help produce and circulate cerebrospinal fluid that bathes the brain and spinal cord of vertebrates 3. Recent research suggests that ependymal cells might function as neural stem cells |
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What are Microglia? |
1. Specialized CNS macrophages ~ respond to signals from neurons; important in mediating responses to injury or disease 2. When the brain is injured or infected, microglia move to the affected area and remove bacteria and cell debris 3. Microglia release signaling molecules that mediate inflammation |
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How are Ion-Specific Channels opened or closed? |
These channels can be opened or closed (they are gated) in response to: 1. a change in voltage across the membrane 2. a chemical (we call this a neurotransmitter) |
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What are Ion-specific Channels? |
the neuron membrane contains integral, transmembrane proteins that serve as channels for specific ions (charged molecules) |
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What are Ligand-Gated Ion Channels? |
When a ligand binds to a specific receptor it opens up the channel and allows Ions to move through |
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What does it mean when a membrane is polarized? |
One side has a different charge than the other |
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what is membrane potential? |
The difference in charge across the plasma membrane |
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What is resting potential? |
When the membrane potential of a neuron is at rest (not firing) |
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What are the two things that determine resting potential? |
1. Difference in concentration of ions in and out of the cell 2. Selective permeability of the plasma membrane to these ions (they only allow certain ones to pass through) |
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What is the ratio for sodium and potassium passing through the pump? |
Sodium 3 potassium 2 |
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Which ion is more permeable through a membrane? |
Potassium |
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What is Graded potential? |
1. Change in membrane potential 2. Local response that varies in magnitude depending on the strength of the applied stimulus 3. Fades out within a few mm of its point of origin |
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What is a depolarized membrane? |
When the membrane potential to becomes less negative than the resting potential |
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What is hyperpolarized membrane? |
Membrane potential becomes more negative than the resting potential |
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What is an Action Potential? |
1. Wave of depolarization that moves down the axon 2. When the threshold level is reached, voltage-activated ion channels open, allowing sodium to flow into the neuron 3. Action potential is generated |
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What does it mean that an action potential is an all-or-none response |
1. No variation exists in the strength of a single impulse 2. Membrane potential either exceeds threshold level, leading to transmission of an action potential, or it does not |
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Describe what is happening at each number |
1. Resting potential 2. Depolarization phase 3. Potassium channels open 4. Repolarization phase 5. undershoot |
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What happens behind an action potential as it moves down the axon? |
repolarization occurs |
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What is the Refractory period? |
Time when it cannot transmit another action potential |
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What are the two different types of Conduction? |
1. Continuous 2. Saltatory |
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What is Continuous conduction? |
1. Takes place in unmyelinated neurons 2. Involves the entire axon plasma membrane |
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What is saltatory conduction? |
1. More rapid than continuous conduction 2. Takes place in myelinated neurons 3. Depolarization skips along the axon from one nodes of Ranvier to the next. |