Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Nucleophiles must have
|
a lone pair
|
|
|
Negatively charged nucleophiles
|
stronger than neutral counterparts
|
|
|
Nucleophile strength trends
|
increases right to left <-------
increases going down |
|
|
Nucleophile bulky groups
|
decrease strength
|
|
|
The weaker the base..
|
the better the L.G.
|
|
|
4 important polar aprotic solvents
|
acetone
DMSO (dimethylsulfoxide) acetonitrile DMF (dimethylformamide) |
|
|
Weak nucleophile
|
H2O, ROH
|
|
|
Strong nucleophile, strong base
|
-OH, -OR
|
|
|
Strong nucleophile, weak base
|
RCOO-, -CN, -SH, -SR, X-, N3-, NH3, amines
|
